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Studies on the pharmacology and toxicology of materials applied to dentine / Wyatt Roderic Hume.Hume, Wyatt Roderic. January 1988 (has links)
Bibliography: leaves 129-146. / ix, 146 leaves : / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / The studies described in this thesis are concerned with the release, diffusion through dentine, local pharmacology and local toxicology of active components of materials which are applied to teeth with therapeutic intent. The method of study of zinc oxide-eugenol (ZOE) release is combined with test methods for cytotoxicity in vitro to give a new model system for the prediction of pulpal toxicity of restorative materials where the potential toxins might be unknown. / Thesis (D.D.S.)--University of Adelaide, Dept. of Dentistry, 1990
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Mercury Amalgam Electrodeposition on Metal MicroelectrodesSaillard, Audric 18 July 2005 (has links)
Mercury amalgam microelectrodes, typically fabricated by electrodeposition of mercury onto metal (platinum, gold, silver) inlaid disks, possess certain advantageous properties for scanning electrochemical microscopy (SECM) and electroanalysis. But as applications require more and more precision, fundamental questions concerning the exact shape and constitution of the amalgam can become important for interpreting SECM experimental data. The purpose of this study is to analyze in depth the formation of the amalgam, in order to provide a better understanding of the key physical processes, and so be able to judge of the accuracy of the currently used models and refine them when necessary.
The amalgam formation is the result of several processes that occur roughly at two different scales: the global scale, which is microscopic, and the local scale, of the order of few nanometers. On the global scale, the dominant physical process is the mass transport, driven almost entirely by diffusion, which determines the rate of mercury deposition. Other phenomena occur at the smaller local scale. Their understanding is essential to predict precisely the volume and shape of the amalgam at shorter times. Among these local phenomena, nucleation and droplet interactions appear critical. The former sets the formation rate and the size of the isolated mercury droplets that are initially formed at the surface of the electrode. An understanding of the latter is necessary to determine the droplet coalescence process.
Among the specific accomplishments of this Master thesis work, a time scale analysis of the global phenomena has been performed leading to the conclusion that quasi-steady state diffusion of mercury ions in the bulk mainly defines the electrodeposition rate. Then, a series of analytical formulations for diffusion-limited electrodeposition current available in the literature has been quickly analyzed, leading to development of analytical/numerical models. These latter have been implemented, and results were critically compared with experimental data, leading to the conclusion that the early electrodeposition was not enough finely modeled. Mercury droplets nucleation and surface interaction have been identified as relevant processes of this period. They have next been investigated in detail, leading to the characterization of the nucleation process, and the derivation of two complimentary approaches on charged droplet stability. Regime maps have been developed, providing first explanations and quantitative information on charged droplet stability dependence on potential applied, electrolyte and droplet size. Finally, through analysis of theoretical predictions, a series of electroanalytical experiments have been proposed for the future validation of the suggested theoretical models.
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Amalgam restorations and mercury toxicitySheridan, Peter January 1992 (has links)
Master of Dental Surgery / The safety of amalgam restorations has been challenged, claims having been made that health risks are associated with the constituent mercury. There are assertions that mercury released from amalgam produces mercury poisoning, and is thus responsible for diverse symptoms of impaired health as well as disease states such as Multiple Sclerosis. This study examines the various forms of mercury and their effects and attempts particularly to delineate the significance of dental amalgam as a factor in hypersensitivity reactions and in the human body burden of mercury. Dental personnel are evaluated as a potentially high-risk group for mercury exposure. Dental amalgam and alternative restorative materials are considered, the removal of amalgam being evaluated as a therapeutic modality. The “anti-amalgam” perspective is scrutinised and the validity of the claims assessed. A review of the scientific literature, and the statements of national and international dental and scientific literature, and the statements of national and international dental and scientific organisations reflect the general support for the safety of dental amalgam. There is no evidence that health risks are associated with the use of dental amalgam other than rare local allergic reactions and oral lichenoid lesions. Notwithstanding the usefulness and safety of dental amalgam certain recommendations and conclusions are made in respect of future approaches to the utilisation of this material and for mercury in general. Further objective scientific research is necessary to determine the effects on human health of chronic exposure to low levels of mercury. There is the need for accurate general population threshold levels to be established for mercury vapour with special consideration for the vulnerable members of the community. The health professions have a significant role to play in providing informed opinion and advice for their patients and the public, in countering the more eccentric claims of the anti-amalgamists and assuaging the anxiety and confusion which accompanies this subject.
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Effect on S̲t̲r̲e̲p̲t̲o̲c̲o̲c̲c̲u̲s̲ m̲u̲t̲a̲n̲s̲ of titanium tetrafluoride in amalgam restorations a thesis submitted in partial fulfillment ... [restorative dentistry] /Pape, Harry R. January 1974 (has links)
Thesis (M.S.)--University of Michigan, 1974.
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The effects of early and delayed finishing and polishing of amalgam restorations on gingival health thesis submitted in partial fulfillment ... restorative dentistry ... /Zajia, Raul A. January 1984 (has links)
Thesis (M.S.)--University of Michigan, 1984.
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Adaptation of dental amalgam to cavity walls a comparison of spherical and conventional alloys by autoradiographic observation of Ca⁴⁵ penetration : a thesis submitted in partial fulfillment ... [restorative dentistry] /Logan, John Curtiss. January 1971 (has links)
Thesis (M.S.)--University of Michigan, 1971.
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Dental amalgam and exposure to mercury in children and adolescents allergologic and immunologic aspects /Herrström, Per. January 1995 (has links)
Thesis (doctoral)--Lund University, 1995. / Added t.p. with thesis statement inserted.
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The effects of bur design on particle size distribution generated by amalgam restoration removal a report submitted in partial fulfillment ... for the degree of Master of Science in Restorative Dentistry ... /Byers, Paul Gorin. January 1998 (has links)
Thesis (M.S.)--University of Michigan, 1998. / Includes bibliographical references.
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Effect on S̲t̲r̲e̲p̲t̲o̲c̲o̲c̲c̲u̲s̲ m̲u̲t̲a̲n̲s̲ of titanium tetrafluoride in amalgam restorations a thesis submitted in partial fulfillment ... [restorative dentistry] /Pape, Harry R. January 1974 (has links)
Thesis (M.S.)--University of Michigan, 1974.
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Adaptation of dental amalgam to cavity walls a comparison of spherical and conventional alloys by autoradiographic observation of Ca⁴⁵ penetration : a thesis submitted in partial fulfillment ... [restorative dentistry] /Logan, John Curtiss. January 1971 (has links)
Thesis (M.S.)--University of Michigan, 1971.
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