Thesis (M. Sc.)--University of Hong Kong, 1993.

Made available in DSpace on 2014-12-17T14:52:50Z (GMT). No. of bitstreams: 1 AdrianaCSO.pdf: 863515 bytes, checksum: 871a8927eaae0dbe402f471e28ab31ac (MD5) Previous issue date: 2006-05-19 / This dissertation of Mestrado investigated the performance and quality of web sites. The target of the research is the proposal of an integrated model of evaluation of services of digital information in web educational sites. The universe of the research was constituted by eighteen Brazilian Universities that offer after-graduation courses, in the levels of mestrado and doutorado in the area of Engineering of Production. The adopted methodology was a descriptive and exploratory research, using the technique of systematic comment and focus group, for the collection of the data, using itself changeable independent dependents and, through the application of two instruments of research. The analysis protocol was the instrument adopted for evaluation and attainment of qualitative results. E the analysis grating was applied for evaluation and attainment of the quantitative results. The qualitative results had identified to the lack of standardization of web sites, under the attributes of content, hierarchy of information, design of the colors and letters. It of accessibility for carriers of auditory and visual special necessities was observed inexistence, as well as the lack of convergence of medias and assistivas technologies. The language of the sites also was evaluated and all present Portuguese only language. The general result demonstrated in grafico and tables with classification of the Universities, predominating the Good note As for the quantitative results, analysis method ed was estatistico, in order to get the descriptive and inferencial result between the dependent and independent variaveis. How much a category of analysis of the services of the evaluated sites, was found it props up and the index generality weighed. These results had served of base for ranking of existence or inexistence the Universities, how much of the information of services in its web sites. In analysis inferencial the result of the test of correlation or association of the independent variaveis (level, concept of the CAPES and period of existence of the program) with the caracteristicas, called was gotten categories of services. For this analysis the estatisticos methods had been used: coefficient of Spearman and the Test of Fisher. But the category you discipline of the Program of Mestrado presented significance with variavel independent and concept of the CAPES. Main conclusion of this study it was ausencia of satandardization o how much to the subjective aspects, design, hierarchy of information navigability and content precision and the accessibility inexistence and convergence. How much to the quantitative aspects, the information services offered by web sites of the evaluated Universities, still they do not present a satisfactory and including quality. Absence of strategies, adoption of tools web, techniques of institucional marketing and services that become them more interactive, navigable is perceived and with aggregate value / Esta disserta??o de Mestrado investigou a performance e qualidade de web sites. O escopo da pesquisa ? a proposi??o de um modelo integrado de avalia??o de servi?os de informa??o digital em web sites educacionais. O universo da pesquisa foi constitu?do por dezoito Universidades brasileiras, que ofertam cursos de p?s-gradua??o, nos n?veis de mestrado e doutorado na ?rea de Engenharia de Produ??o. A metodologia adotada foi uma pesquisa descritiva e explorat?ria, utilizando a t?cnica de observa??o sistem?tica e o focus group, para a coleta dos dados, utilizando-se vari?veis dependentes e independentes, atrav?s da aplica??o de dois instrumentos de pesquisa. O protocolo de an?lise foi o instrumento adotado para avalia??o e obten??o de resultados qualitativos. E a grade de an?lise foi aplicada para avalia??o e obten??o dos resultados quantitativos. Os resultados qualitativos identificaram a falta de padroniza??o dos web sites, sob os atributos de conte?do, hierarquia de informa??es, design das cores e letras. Observou-se a inexist?ncia de acessibilidade para portadores de necessidades especiais auditivas e visuais, bem como a falta de converg?ncia de m?dias e tecnologias assistivas. O idioma dos sites, tamb?m foi avaliado e todos apresentam o portugu?s como ?nico idioma. O resultado geral ? demonstrado em gr?fico e tabelas com a classifica??o das Universidades, predominando a nota Bom. No que se refere aos resultados quantitativos, o m?todo de an?lise adotado foi estat?stico, a fim de obter o resultado descritivo e inferencial entre as vari?veis dependentes e independentes. Quanto ? categoria de an?lise dos servi?os dos sites avaliados, foi encontrado o Escore M?dio Ponderado (EGP) e o ?ndice Geral Ponderado (IGP). Esses resultados serviram de base para o ranking das Universidades, quanto ? exist?ncia ou inexist?ncia dos servi?os de informa??o nos seus web sites. Na an?lise inferencial foi obtido o resultado do teste de correla??o e associa??o das vari?veis independentes (n?vel, conceito da CAPES e per?odo de exist?ncia do programa) com as caracter?sticas, denominadas categorias de servi?os. Para esta an?lise foram usados os m?todos estat?sticos: coeficiente de Spearman e o Teste de Fisher. Apenas a categoria Disciplinas do Programa de Mestrado apresentou signific?ncia com a vari?vel independente conceito da CAPES. A principal conclus?o deste estudo ? a aus?ncia de padroniza??o quanto aos aspectos subjetivos, design, hierarquia da informa??o, navegabilidade e precis?o de conte?do e a inexist?ncia de acessibilidade e converg?ncia. Quanto aos aspectos quantitativos, os servi?os de informa??o ofertados pelos web sites das Universidades avaliadas, ainda n?o apresentam uma qualidade satisfat?ria e abrangente. Percebe-se aus?ncia de estrat?gias, de ado??o de ferramentas web, de t?cnicas de marketing institucional e servi?os que os tornem mais interativos, naveg?veis e com valor agregado

The thesis investigates the concepts of archaeological spatial association within the context of both site and regional data sets. The techniques of geophysical surveying, surface distribution collection and aerial photography are described and discussed. Several new developments of technique are presented as well as a detailed discussion of the problems of data presentation and analysis. The quantitative relationships between these data sets are explored by modelling them as operands and describing association in terms of operators. Both local and global measures of association are considered with a discussion as to their relative merits. Methods for the spatial association of regional lattice and point processes are developed. A detailed discussion of distance based spatial analysis techniques is presented.

The number of experimentally resolved protein structures in the Protein Data Bank has been growing fast in the last 20 years, which motivates the develop- ment of many computational tools for protein-ligand binding sites prediction. Binding sites prediction from protein 3D structure has many important applica- tions; it is an essential step in the complex process of rational drug design, it helps to infer the side-effects of drugs, it provides insight into proteins biological functions and it is helpful in many other fields, such as protein-ligand docking and molecular dynamics. As far as we know, there has not been a study that would systematically investigate general properties of known ligand binding sites on a large scale. In this thesis, we examine these properties using existing experimen- tal and predicted residue-level annotations of protein sequence and structure. We present an automated pipeline for statistical analysis of these annotations, based on hypothesis testing and effect size estimation. It is implemented in Python and it is easily extensible by user-defined annotations. The usage is demonstrated on 33 existing annotations and 4 different datasets. The practical significance of the results is tested with P2Rank prediction method. We hope that the results as well as the pipeline...