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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
431

Rhenium cyclized [alpha]-MSH analogs, somatostatin analogs and T-antigen avid peptides as imaging and therapeutic agents for tumor targeting

Cheng, Zhen, January 2001 (has links)
Thesis (Ph. D.)--University of Missouri-Columbia, 2001. / Typescript. Vita. Includes bibliographical references. Also available on the Internet.
432

The role of cysteine proteases in MHC class II antigen processing and presentation /

Beers, Courtney. January 2004 (has links)
Thesis (Ph. D.)--University of Washington, 2004. / Vita. Includes bibliographical references (leaves 96-108).
433

Rhenium cyclized [alpha]-MSH analogs, somatostatin analogs and T-antigen avid peptides as imaging and therapeutic agents for tumor targeting /

Cheng, Zhen, January 2001 (has links)
Thesis (Ph. D.)--University of Missouri-Columbia, 2001. / Typescript. Vita. Includes bibliographical references. Also available on the Internet.
434

A new immunoassay for quantification of a novel cancer antigen in serum and immunostaining of carcinoma tissues and cultured cells revealing the antigenic cellular location /

McDuffee, Emily. January 2002 (has links) (PDF)
Thesis (Ph. D.)--East Tennessee State University, 2002. / Includes bibliographical references. Also available via Internet at the UMI web site.
435

Structural and dynamical investigations of the interaction between the MUC1 tumor antigen and the humoral immune system : towards the design of a second generation cancer vaccine /

Schuman, Jason Tyler. January 2003 (has links)
Thesis (Ph. D.)--University of Washington, 2003. / Vita. Includes bibliographical references (leaves 178-187).
436

AT-repeat polymorphisms of the human CTLA-4 gene : associations with autoimmune diabetes and allele-specific variation of expression /

Lowe, Robert M. J., January 2003 (has links)
Thesis (Ph. D.)--University of Washington, 2003. / Vita. Includes bibliographical references (leaves 105-118).
437

Functional characterization and therapeutic implication of CD47 in sorafenib resistance in hepatocellular carcinoma

Lo, Jessica, 盧姵岐 January 2014 (has links)
abstract / Pathology / Master / Master of Philosophy
438

Isolation of human leukocyte antigen G/cytokeratin 7 positive fetal cells from transcervical samples for potential use in prenatal genetic diagnosis

Wong, Hoi-hei, Vera, 王愷曦 January 2015 (has links)
There has been an increase in rates of chromosomal abnormalities in newborns as a result of reproductive aging. For the past decades, a lot of effort has been placed on identifying pregnancies at risk of genetic defects. Conventional prenatal genetic diagnosis is achieved by invasive procedures that have been associated with an increased risk of pregnancy loss. This has led the researchers to explore the use of non-/minimally invasive techniques for prenatal diagnosis. Trophoblasts are known to be shed from regressing chorionic villi into the lower uterine pole of pregnant women during the first trimester. These cells are trapped within cervical mucus, which can be retrieved with a cytobrush. By using human leukocyte antigen G (HLA-G) and cytokeratin-7 (CK7) as trophoblast markers, this study aims to investigate the possibility of isolating individual fetal trophoblast from transcervical samples for genetic diagnosis. 195 healthy pregnant women requesting for legal termination of pregnancy (TOP) were recruited in this study. Transcervical cells were collected from them with the use of a cytobrush before TOP. HLA-G+ or CK7+ cells were then isolated by a combination of mucolytic action, fluorescent immunohistochemistry, and micromanipulation. The origin of these cells was subsequently investigated by either fluorescent in situ hybridization (FISH) or allelic profiling by quantitative fluorescent polymerase chain reaction (QF-PCR) based on chromosome 16, chromosome X, amelogenin gene and sex determining region Y (SRY) gene. This study first demonstrated the presence of fetal cells in transcervical samples based on the detection of chromosome Y signal by ordinary PCR. Cells expressing HLA-G and CK7 were also identified among transcervical cells. Immunopositive cells were isolated by micromanipulation under fluorescent microscopy. One isolated cell expressing CK7 was shown to inherit paternal allele at a locus on chromosome 16, suggesting the possible fetal origin of this cell. However, this study was still hampered by a number of technical factors. Further optimization of the protocol is required before transcervical trophoblasts can be retrieved in a reliable manner. / published_or_final_version / Obstetrics and Gynaecology / Master / Master of Philosophy
439

Expression and mutations of fas gene in oesophageal cancer

Lee, Ping-yin., 李炳賢. January 2003 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences
440

Serodiagnosis of Penicilliosis marneffei in HIV & non-HIV patients using a recombinant antigen Mp1p

Hui, Wai-ting., 許偉廷. January 2000 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences

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