Global ETD Search

31	Studies of novel anticancer agents : progress towards leiodermatolide and the total synthesis of analogues and hybrids of dictyostatin, discodermolide and taxol Naylor, Guy James January 2011 (has links) No description available. 540 Antineoplastic agents
32	Phytochemical investigation of Croton californicus family Euphorbiaceae Luzbetak, Doris Janet January 1978 (has links) No description available. Antineoplastic agents. Euphorbiaceae.
33	The synthesis of derivatives of antitumor agents related to cephalotaxine Freeman, Richard Max, 1949- January 1974 (has links) No description available. Antineoplastic agents. Cephalosporins.
34	Isolation of plant-derived signal transduction inhibitors : potential antitumor agents Saylor, Melissa Anne 12 1900 (has links) No description available. Antineoplastic agents Medicinal plants
35	Approaches to the synthesis of xanthone analogs of the anthracycline class of anticancer agents Mancini, Michael. January 1985 (has links) Several strategies outlining approaches to the synthesis of the heteroanthracyclinones 4-demethoxyxanthodaunomycinone and 4-demethoxyisoxanthodaunomycinone (7,8,9,10-tetrahydrobenzo(b)-6,7,9,11-tetrahydroxy-9-acetylxanthen-12 and 5-one) are described. / The condensation of tetralin 2-acetyl-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthol with o-methoxybenzoic acid was investigated and useful large-scale syntheses of important 1,4-dimethoxy-substituted xanthone intermediates were developed. / Diels-Alder cycloaddition reaction between a xanthone-derived o-quinodimethane intermediate and an olefin afforded a low yield of adduct. On the other hand, excellent yields of isolable but labile adducts were obtained in the cycloaddition reaction between xanthoquinone (and also thioxanthoquinone) and Danishefsky's dienes. The formation of linear vs internal adducts was rationalized on the grounds of resonance and FMO theory. Efforts to induce unactivated dienes to cycloadd using catalysts as well as annulation studies on model compounds using the novel reagent (E)-N-vinylpyrrolidine-(beta)-(2-lithio-1,3-dithian-2-yl) (as a synthon of the (alpha),(beta)-dianion of acetaldehyde) are discussed. / The synthesis of daunomycin and xanthodaunomycin analogs carrying a carbon substituent at position 7 were not accessible using the Diels-Alder cycloaddition reaction as diene 1-carbomethoxy-3-triethylsilyloxy-1,3-butadiene failed to react with either quinizarinquinone or xanthoquinone even at elevated temperatures. / The compound 4-hydroxy-1- 2- (2-hydroxyethyl)amino ethyl amino xanthone and the 4-methoxy derivative were prepared and found to be inactive in the in vivo P-388 mouse leukemia model system. Antineoplastic agents. Anthracyclines.
36	The potential clinical applications of garlic-derived S-allylmercaptocysteine in the treatment of hormone refractory prostate cancer / Howard, Edward William. January 2007 (has links) Thesis (Ph. D.)--University of Hong Kong, 2007. / Also available online.
37	Pharmacokinetic studies on cladribine / Lindemalm, Synnöve, January 2001 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2001. / Härtill 6 uppsatser.
38	Microphysiometry in the evaluation of cytotoxic drugs with special emphasis on the novel cyanoguanidine CHS 828 / Ekelund, Sara, January 1900 (has links) Diss. (sammanfattning) Uppsala : Univ., 2001. / Härtill 5 uppsatser. Antineoplastic agents: pharmacology.
39	Pharmacological studies of CHS 828 and etoposide induced tumour cell death / Martinsson, Petra 1974- January 1900 (has links) Diss. (sammanfattning) Uppsala : Univ., 2001. / Härtill 5 uppsatser.
40	Cloning and characterization of human deoxyribonucleoside kinases : phosphorylation of anti-cancer and anti-viral nucleoside analogs / Johansson, Magnus, January 1900 (has links) Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 6 uppsatser. Antineoplastic agents: metabolism.

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