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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
11

Optimization and extensions of the nucleophile catalyzed aldol-lactonization (NCAL) process for bicyclic beta-lactone synthesis: applications to piperidine, pyrrolidine, and gamma-lactam-fused beta-lactones

Oh, Seongho 16 August 2006 (has links)
The intramolecular nucleophile catalyzed aldol-lactonization (NCAL) process was optimized successfully. A variety of C9-acylated cinchona alkaloids were synthesized and used for NCAL reactions with non-activated aldehydes. New pyridinium salts, derivatives of Mukaiyama’s reagent, led to marked improvements in efficiency for the catalytic, asymmetric NCAL process while maintaining high enantioselectivity. Larger scale versions of the catalytic, asymmetric NCAL reaction were also developed allowing practical access to chiral bicyclic b-lactones. As an extension of the intramolecular NCAL process, pyrrolidine and piperidine fused blactones were synthesized. Simple g-lactam fused b-lactones were synthesized as a model study for omuralide, salinosporamide A, and derivative synthesis. Synthesis of asubstituted aldehyde acids was extensively studied but steric effects from both acid and amine moieties led to great difficulties in this approach.
12

Synthesis of atropisomeric 1-Naphthamide-Derived phosphines and application for asymmetric heck and Suzuki-Miyaura reactions /

Sun, Lijie. January 2009 (has links)
Includes bibliographical references (p. 176-187).
13

X-ray crystal structures of inhibited bovine pancreatic trypsin

Bertrand, Jay Aaron 08 1900 (has links)
No description available.
14

Approaches to the asymmetric synthesis of 2-arylpropanoic acids / by Josephine Louise Newton.

Newton, Josephine Louise January 1995 (has links)
Bibliography : leaves 200-206. / iv, 206 leaves ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Covers the asymmetric synthesis of 2-arylpropanoic acids including ketoprofen, ibuprofen, ximoprofen. / Thesis (Ph.D.)--University of Adelaide, Dept. of Chemistry, 1995
15

Synthesis and reactions of a non-racemic, bicyclic chiral auxiliary / by Jeffrey William Holman.

Holman, Jeffrey William January 1992 (has links)
Bibliography: leaves 213-218. / v, 218 leaves ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, Dept. of Organic Chemistry, 1993
16

The asymmetric synthesis of polyfunctional pyrrolidine alkaloids and their analogues

Lindsay, Karl B. January 2003 (has links)
Thesis (Ph.D.)--University of Wollongong, 2003. / Typescript. Includes bibliographical references: leaf 214-222.
17

Studies on the optimization of catalytic asymmetric aziridination reaction tactics and mechanism /

Lu, Zhenjie. January 2008 (has links)
Thesis (Ph. D.)--Michigan State University. Dept. of Chemistry, 2008. / Title from PDF t.p. (viewed on Mar. 30, 2009) Includes bibliographical references (p. 375-386). Also issued in print.
18

The asymmetric synthesis of polyhydroxylated pyrrolizidine alkaloids

Tang, Minyan. January 2004 (has links)
Thesis (Ph.D.)--University of Wollongong, 2004. / Typescript. Includes bibliographical references: leaf 236-249.
19

De novo asymmetric synthesis of digitoxin based carbohydrate libraries

Xin, Wenjun. January 1900 (has links)
Thesis (M.S.)--West Virginia University, 2007. / Title from document title page. Document formatted into pages; contains x, 67 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 37-38).
20

The use of chiro-inositols in asymmetric synthesis

Singleton, Jamie Andrew. January 2008 (has links)
Thesis (Ph.D.)--University of Wyoming, 2008. / Title from PDF title page (viewed on August 3, 2009). Includes bibliographical references (p. 125-129).

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