A challenge to research on auditory and speech perception has been a lack of correlation between measures of each ability, despite their shared acoustical basis. The hypothesis presented here is that stimuli in the auditory domain stimuli generally have a static quality whereas stimuli in the speech domain generally have a dynamic quality, but attempts to correlate the two assume that static and dynamic stimuli are processed similarly by auditory short-term memory (ASTM). This thesis utilizes a change-detection task, which is popular for investigating the function of visual short-term memory, to more closely examine the function of ASTM for the purpose of evaluating the plausibility of this hypothesis. Across three experiments the temporal dynamics of ASTM are explored by manipulating the interstimulus interval (ISI), the stimulus duration, and the type of feature change in a change-detection task. This final manipulation (Experiment 3) also involves change-detection in a sequence of stimuli rather than just pairs of stimuli (as in Experiments 1 & 2). Individual differences in ASTM function are also evaluated in order to ensure that any differences found are present for all listeners and to further understand the function of ASTM. It is found that ASTM for static stimuli is consistently better than dynamic stimuli, even for listeners with high ASTM performance. Longer ISIs lead to poorer performance only for dynamic stimuli and only for participants who show poor ASTM function at long ISIs. Longer durations lead to better performance for all stimuli to a point, but performance for dynamic stimuli plateaus, and even decreases, at the longest durations, while the static stimuli continue to show gains. This result generally holds for all listeners. Lastly, changes in temporal order and changes to stimuli at the end of the sequence are detected more often than changes in frequency and large changes are detected more often than small changes. These first two effects hold for all stimuli while the second effect is more true of static stimuli. These results are discussed within the context of ASTM and the impact of each manipulation on the encoding, maintenance, and comparison processes is considered.

This research explores auditory short-term memory (STM) capacity for non-linguistic sounds in 10-month-old infants. Infants were presented with auditory streams composed of repeating sequences of either 2 or 4 unique instruments (e.g., flute, piano, cello; 350 or 700. ms in duration) followed by a 500-ms retention interval. These instrument sequences either stayed the same for every repetition (Constant) or changed by 1 instrument per sequence (Varying). Using the head-turn preference procedure, infant listening durations were recorded for each stream type (2- or 4-instrument sequences composed of 350- or 700-ms notes). Preference for the Varying stream was taken as evidence of auditory STM because detection of the novel instrument required memory for all of the instruments in a given sequence. Results demonstrate that infants listened longer to Varying streams for 2-instrument sequences, but not 4-instrument sequences, composed of 350-ms notes (Experiment 1), although this effect did not hold when note durations were increased to 700. ms (Experiment 2). Experiment 3 replicates and extends results from Experiments 1 and 2 and provides support for a duration account of capacity limits in infant auditory STM.

La présente étude vise à approfondir les connaissances relatives aux mécanismes neuronaux qui sous-tendent la maintenance de sons variant en hauteur dans la mémoire auditive à court terme (MACT), plus précisément lors de sa saturation. À cet effet, la technique des potentiels reliés aux évènements (PRE) en électrophysiologie a été utilisée. La sélection des participants s’est déroulée par l’entremise de deux expériences comportementales : l’une était une tâche de discrimination et l’autre, une tâche qui évaluait l’habileté générale des participants à réussir une tâche similaire à celle de l’expérience principale en électroencéphalographie (EEG). Les résultats comportementaux de notre tâche en EEG ont montré que la performance diminuait de façon significative plus la charge en mémoire augmentait (séquences de 2, 4, 6 et 8 sons) et que l’estimation de la capacité de la MACT mesurée par K augmentait entre 2 et 4 sons pour atteindre un plafond à 4 sons (effet plafond). Le K maximum étant de 2.84 sons, l’empan mnésique (EM) auditif semble être près de 3 sons. Les résultats électrophysiologiques ont montré que la composante électrophysiologique reliée à la maintenance de sons en MACT, la Sustained Anterior Negativity (SAN), était modulée par le nombre de sons à maintenir : son amplitude augmentait de 2 à 4 sons et ce, jusqu’à l’atteinte d’un plafond à 4 sons. Ces résultats suggèrent que la maintenance de sons additionnels dans la MACT n’est plus possible après sa saturation. Nous soutenons donc que la SAN est un index électrophysiologique de l’activité neuronale associée à la maintenance d’items auditifs dans la MACT et que son amplitude est un bon indicateur de la capacité individuelle de la MACT, estimée par K. Des résultats post-hoc ont démontré que les musiciens et les non-musiciens tendent à avoir des différences au niveau de la SAN, sans pour autant modifier l’effet de charge en mémoire. Une analyse qualitative et quantitative de l’utilisation des stratégies mnésiques ont permis de clarifier leur implication et leur nature au sein d’une tâche cognitive de mémoire, plus précisément en audition. Pour conclure, l’ensemble de ces résultats suggère également que la SAN est reliée à la maintenance de sons dans la MACT et ainsi, un bon indicateur de sa capacité. / The aim of the current study is to further understand, through the use of event-related potentials (ERPs), the neural mechanisms that underlie the maintenance of pitch in auditory short-term memory (ASTM) after reaching the memory span. Two behavioral experiments were used to help perform the selection of the participants: the first one was an evaluation of the acoustic discrimination and the second one was a general evaluation of participants’ ability to succeed to a similar task of the one that will be used in the electrophysiological (EEG) part of the experiment. Behavioral results from the EEG task showed a significant decrease in accuracy when the load increased (sequences of 2, 4, 6 and 8 tones). The estimation of the memory capacity (named K), increased from load 2 to 4 and reached a plateau after 4 tones. The maximum K represented 2.84 tones; the auditory span seems to be around 3 tones. Experimental results showed that the ERP component related to the maintenance of tones in ASTM, as measured by the Sustained Anterior Negativity (SAN), was modulated by the load. More specifically, its amplitude increased when the load increased (from 2 to 4) and reached a plateau at load 4. These results suggest that the maintenance of additional tones in ASTM is not possible after its saturation. Thus, the SAN appears to be an adequate electrophysiological index of neuronal activity related to the maintenance of tones in ASTM, and its amplitude appears to be predicted by K. Post-hoc results showed that musician and non-musicians tend to have some differences in their electrophysiological results; however, no change related to the load effect was observed. Finally, a qualitative and quantitative analysis was done to investigate the impact of the use of different mnemonic strategies in ASTM. Taking together, our results support that the SAN component is related to the maintenance of tones in ASTM and can be considerate as a good indicator of its capacity.

Ce travail de thèse vise à améliorer notre compréhension des mécanismes sous-tendant la perception et la mémorisation des structures sonores complexes. Nous avons étudié les corrélats comportementaux et cérébraux de la perception et de la mémoire auditive pour des notes isolées, des séquences musicales et des séquences de mots, chez des auditeurs typiques et dans l'amusie congénitale, un trouble permanent de la perception de la musique. En utilisant des approches comportementales, nous avons démontré que les déficits des individus amusiques dans la dimension de la hauteur sont liés à des déficits à la fois durant l’encodage des sons courts et dans la rétention à court terme de l'information musicale. En utilisant des mesures neurophysiologiques (IRM, MEG, IRMf) nous avons démontré l’existence d’anomalies anatomiques et fonctionnelles dans le cerveau amusique, principalement dans les cortex frontal et auditif droits. De plus des anomalies fonctionnelles ont été observées à la fois durant l'encodage, la rétention et la reconnaissance de l'information mélodique lors d’une tâche de mémoire à court terme. En revanche, pour le matériel verbal, les participants amusiques recrutaient des régions cérébrales similaires à celles des contrôles, ceci suggérant que des ressources neuronales distinctes sous-tendent la mémoire tonale et verbale. A partir des conclusions de ces trois premières études, nous avons exploré deux approches visant à renforcer les capacités de traitement de la hauteur dans l'amusie: 1) en étudiant si des connaissances implicites du système musical occidental tonal pouvaient améliorer leurs capacités de mémoire à court terme pour les notes, et 2) en explorant si les capacités d’encodage altérées des participants amusiques pouvaient être améliorées par des interactions audio-visuelles. Ces études ont été encourageantes et pourraient guider la conception d'outils de réhabilitation dans ce déficit. Enfin, il convient de souligner que nos recherches contribuent également à améliorer la compréhension des mécanismes sous-tendant le traitement de la musique en général, un domaine de recherche émergeant qui fait le parallèle avec le traitement du langage / The aim of this PhD thesis is to further our understanding about how humans perceive and nmemorize complex sound structures. We investigated the behavioral and cerebral correlates of auditory perception and memory for isolated tones, musical sequences, and verbal material both in typical listeners and in individuals presenting a lifelong disorder of music perception that has been referred to as congenital amusia. Using behavioral approaches, we demonstrated that amusic individuals’ deficits in the pitch dimension are related to impairments both in the encoding of short tones and in the short term retention of pitch information. Using multimodal neuroimaging methods (MRI, MEG, fMRI) we observed anatomical and functional abnormalities in the amusic brain, mostly in the right frontal cortex and in the right auditory cortex. Functional abnormalities were observed at each level of processing in short-term memory tasks, that is for encoding, retention, and retrieval of the melodic information. In contrast, for verbal material, amusic participants recruited similar brain regions as those observed for controls, thus suggesting that separate neural resources support tonal and verbal memory. Based on the conclusions made on these first three studies, we explored two approaches aiming to boost pitch processing abilities in amusia; 1) by investigating whether implicit knowledge of the western tonal musical system could influence their short-term memory abilities, and 2) by exploring whether amusic individuals’ altered encoding of short tones could be improved by audio-visual interactions These investigations were encouraging and provide the first steps toward designing tools of rehabilitation in this musical disorder. To conclude, it is worth underlining that these studies also improve our understanding of music processing in general, which is the subject of an increasing research domain that is often making the parallel to language processing