A device for performing an objective eye exam has been developed to automatically determine ophthalmic prescriptions. The closed loop fluidic auto-phoropter has been designed, modeled, fabricated and tested for the automatic measurement and correction of a patient's prescriptions. The adaptive phoropter is designed through the combination of a spherical-powered fluidic lens and two cylindrical fluidic lenses that are orientated 45° relative to each other. In addition, the system incorporates Shack-Hartmann wavefront sensing technology to identify the eye's wavefront error and corresponding prescription. Using the wavefront error information, the fluidic auto-phoropter nulls the eye's lower order wavefront error by applying the appropriate volumes to the fluidic lenses. The combination of the Shack-Hartmann wavefront sensor the fluidic auto-phoropter allows for the identification and control of spherical refractive error, as well as cylinder error and axis; thus, creating a truly automated refractometer and corrective system. The fluidic auto-phoropter is capable of correcting defocus error ranging from −20D to 20D and astigmatism from −10D to 10D. The transmissive see-through design allows for the observation of natural scenes through the system at varying object planes with no additional imaging optics in the patient's line of sight. In this research, two generations of the fluidic auto-phoropter are designed and tested; the first generation uses traditional glass optics for the measurement channel. The second generation of the fluidic auto-phoropter takes advantage of the progress in the development of holographic optical elements (HOEs) to replace all the traditional glass optics. The addition of the HOEs has enabled the development of a more compact, inexpensive and easily reproducible system without compromising its performance. Additionally, the fluidic lenses were tested during a National Aeronautics Space Administration (NASA) parabolic flight campaign, to determine the effect of varying gravitational acceleration on the performance and image quality of the fluidic lenses. Wavefront analysis has indicated that flight turbulence and the varying levels of gravitational acceleration ranging from zero-G (microgravity) to 2G (hypergravity) had minimal effect on the performance of the fluidic lenses, except for small changes in defocus; making them suitable for potential use in a portable space-based fluidic auto-phoropter.

Adaptive optic technology has revolutionized real time correction of wavefront aberrations. Optofluidic based applied optic devices have offered an opportunity to produce flexible refractive lenses in the correction of wavefronts. Fluidic lenses have superiority relative to their solid lens counterparts in their capabilities of producing tunable optical systems, that when synchronized, can produce real time variable systems with no moving parts. We have developed optofluidic fluidic lenses for applications of applied optical devices, as well as ophthalmic optic devices. The first half of this dissertation discusses the production of fluidic lenses as optical devices. In addition, the design and testing of various fluidic systems made with these components are evaluated. We begin with the creation of spherical or defocus singlet fluidic lenses. We then produced zoom optical systems with no moving parts by synchronizing combinations of these fluidic spherical lenses. The variable power zoom system incorporates two singlet fluidic lenses that are synchronized. The coupled device has no moving parts and has produced a magnification range of 0.1 x to 10 x or a 20 x magnification range. The chapter after fluidic zoom technology focuses on producing achromatic lens designs. We offer an analysis of a hybrid diffractive and refractive achromat that offers discrete achromatized variable focal lengths. In addition, we offer a design of a fully optofluidic based achromatic lens. By synchronizing the two membrane surfaces of the fluidic achromat we develop a design for a fluidic achromatic lens.The second half of this dissertation discusses the production of optofluidic technology in ophthalmic applications. We begin with an introduction to an optofluidic phoropter system. A fluidic phoropter is designed through the combination of a defocus lens with two cylindrical fluidic lenses that are orientated 45° relative to each other. Here we discuss the designs of the fluidic cylindrical lens coupled with a previously discussed defocus singlet lens. We then couple this optofluidic phoropter with relay optics and Shack-Hartmann wavefront sensing technology to produce an auto-phoropter device. The auto-phoropter system combines a refractometer designed Shack-Hartmann wavefront sensor with the compact refractive fluidic lens phoropter. This combination allows for the identification and control of ophthalmic cylinder, cylinder axis, as well as refractive error. The closed loop system of the fluidic phoropter with refractometer enables for the creation of our see-through auto-phoropter system. The design and testing of several generations of transmissive see-through auto-phoropter devices are presented in this section.