Background: Avian influenza is a serious infectious disease attracting great concerns of the world. It not only results in a huge economic loss but also poses a great threat to public health, and poultry production plays a major role of transmission as well as a locus of pathogen evolution, mutation and adaptation of avian influenza virus between wild birds and humans. Therefore, biosecurity measures along the poultry supply chains are important to prevent and control avian influenza. My objective was to summarize the past and present various measures against avian influenza in the industrial, commercial and backyard poultry production systems. Methods: A literature search was performed by PubMed, HKU Scholar Hub and Google. Based on the inclusion criterion and exclusion criterion, the relevant articles were selected with full text in English up to 11st, July 2013. Results: A total of 18 articles were found among the 474 potentially relevant articles. Among these articles, 17articlescame from PubMed and 1 article came from HKU Scholar Hub; 2 articles were closely related to industrial poultry production, 9 articles were closely related to commercial poultry production, 3 articles were closely related to village, rural or backyard poultry production and the rest 4 articles mixed the biosecurity measures in the different poultry production systems. These articles covered various biosecurity measures such as surveillance and monitoring, segregation, cleaning and disinfection, vaccination, training for workers, stamping out, controlling markets and poultry management in the developing and developed countries. Discussion: The common control measures are discussed and the biosecurity is aneffective way to prevent the avian influenza outbreaks in poultry and then to protect the health of all people. However, there were still limitations when implementing biosecurity. Due to local social, cultural, economic, psychological and political factors, it is difficult to prevent and control the avian influenza outbreaks in the poultry supply chains only by one single measure or individual. Therefore, some recommendations referring to cooperation of public and private sectors, comprehensiveness and specifity of measures, improving risk perception and education were discussed. / published_or_final_version / Public Health / Master / Master of Public Health