The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on September 10, 2009). Thesis advisor: Dr. Satish S. Nair, Dr. Jeffery T. Potts. Includes "Presentations and Publications" by author. Includes bibliographical references.

Thesis (Ph.D.)--University of Rhode Island, 2005. / Includes bibliographical references (leaves 90-95).

Thesis (M.S.)--Iowa State University, 2005. / Includes bibliographical references (leaves 31-34).

Thesis (M.S.)--Iowa State University, 2005. / Includes bibliographical references (leaves 31-34). Also available online (PDF file) by a subscription to the set or by purchasing the individual file.

Resetting of baroreceptor afferent firing in hypertensive animals, and the reduction in baroreflex regulation of the heart rate seen in man, are thought to be secondary to changes in vascular distensibility in hypertension. Diminished baroreflex sensitivity should be reflected in a withdrawal of inhibition of sympathetic nervous function. This hypothesis was investigated in 62 hypertensive subjects using three indirect indices of sympathetic nervous activity: (1) the haemodynamic responses to mental and physical exercise, (2) plasma noradrenaline concentrations at rest, and on exercise, and (3) the beat-to-beat variability of waking ambulatory blood pressure. Subjects with diminished baroreflex sensitivity (1) achieved higher maximum mean arterial blood pressures during four different exercises, and greater absolute increases in blood pressure when bicycling, (2) tended (P<O.O6) to have higher plasma noradrenaline concentrations when bicycling, and (3) exhibited greater variability of their waking mean arterial pressure. It was concluded that subjects with reduced baroreflex sensitivity were less able to buffer acute changes in blood pressure, and inhibit sympathetic efferent activity, particularly when somatic afferents were also activated, as in physical exercise. The time course and extent of changes in baroreflex sensitivity, in relation to changes in the heart and (by inference from previous work) the peripheral vasculature, during the development and reversal of 2-kidney 1-clip Goldblatt hypertension was investigated in rats. A reduction in baroreflex sensitivity occurred within three days of renovascular hypertension, before the occurrence of cardiovascular changes and resetting of the threshold for carotid sinus activation. Baroreflex sensitivity returned to normal one day after the reversal of renovascular hypertension, at a time when these structural changes were still present. It was concluded that 'non-structural', rather than 'structural' factors were responsible for the reduction in baroreflex sensitivity during the initial stages of renovascular hypertension.

Thesis (Ph. D.)--Florida State University, 2005. / Advisor: Robert J. Contreras, Florida State University, College of Arts and Sciences, Dept. of Psychology. Title and description from dissertation home page (viewed Jan. 24, 2006). Document formatted into pages; contains vi, 58 pages. Includes bibliographical references.

Baroreflex function and cardiovascular responses to lower body negative pressure during selective autonomic blockade were evaluated in endurance exercise trained (ET) and untrained (UT) men. Baroreflex function was evaluated using a progressive intravenous infusion of phenylephrine HCL (PE) to a maximum of 0.12 mg/min. Heart rate, arterial blood pressure, cardiac output and forearm blood flow were measured at each infusion rate of PE. The reduction in forearm blood flow and concomitant rise in forearm vascular resistance was the same for each subject group. However, the heart rate decreases per unit increase of systolic or mean blood pressure were significantly (P<.05) less in the ET subjects (0.91 ± 0.30 versus 1.62 ± 0.28 for UT). During progressive lower body negative pressure with no drug intervention, the ET subjects had a significantly (P<.05) greater fall in systolic blood pressure (33.8 ± 4.8 torr versus 16.7 ± 3.9 torr). However, the change in forearm blood flow or resistance was not significantly different between groups. Blockade of parasympathetic receptors with atropine (0.04 mg/kg) eliminated the differences in response to lower body negative pressure. Blockade of cardiac sympathetic receptors with metoprolol (0.02 mg/kg) did not affect the differences observed during the control test. It was concluded that the ET subjects were less effective in regulating blood pressure than the UT subjects, because of 1) an attenuated baroreflex sensitivity, and 2) parasympathetic-mediated depression of cardiac and vasoconstrictive responses to the hypotensive stress.

During dynamic exercise the arterial baroreflexes have been thought to reset to the prevailing level of systemic pressure in order to modulate transient changes in blood pressure with the same sensitivity (gain) as at rest. To test this hypothesis, cardiovascular responses to dynamic exercise and carotid baroreflex responses to graded neck suction and neck pressure (NS/NP) were examined in seven men of moderate fitness (V02 = 41.4±3.6 ml O2*kg^-1*min^-1) during two levels (20% and 40% of peak oxygen uptake) of steady-state exercise. In addition, deactivation of cardiopulmonary baroreceptors has been thought to increase carotid baroreflex responsiveness in the quiescent state in man.

The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on January 5, 2010). Thesis advisor: Paul J. Fadel. "December 2009" Includes bibliographical references.

Chen Fei. / "October 2004." / Thesis (Ph.D.)--Chinese University of Hong Kong, 2004. / Includes bibliographical references. / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Mode of access: World Wide Web. / Abstracts in English and Chinese.