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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
21

Raman spectroscopy of supported lipid bilayers and membrane proteins

Lee, Chongsoo January 2005 (has links)
Off-resonance unenhanced total internal reflection (TIR) Raman Spectroscopy was explored to investigate supported single lipid bilayers with incorporated membrane peptides/proteins at water/solid interface. A model membrane was formed on a planar supported lipid layer (pslb) by the fusion of the reconstituted small unilamellar vesicles (SUVs), and the intensity of bilayer was confirmed by a comparison of Raman spectral intensity in the C-H stretching modes with C<sub>16</sub>TAB. With prominent Raman sensitivity attained, we studied the 2-D phase transition of DMPC and DPPC pslbs and the temperature-dependent polarised spectra revealed a broad transition range of ca. 10 °C commencing at the calorimetric phase transition temperature. We applied polarised TIR-Raman Spectroscopy to pslbs formed by DMPC SUVs reconstituted with a model membrane-spanning peptide gramicidin D. A preferential channel structure formed by dissolution of trifluoroethanol could be probed by polarised Raman Spectroscopy qualitatively showing an antiparallel β-sheet conformation (different from "standard" one) and our Raman spectra by correlation with NMR and CD data confirmed single-stranded π<sup>6.3</sup> β-helical channel structure in the single bilayer. We also studied the membrane-penetrating peptide indolicidin in the presence of DMPC pslb over the chain melting temperature and a β-turn structure was dominantly observed concomitant with membrane perturbation. Dynamic adsorption of DPPC to form pslb from a micellar solution of n-dodecyl-β- <sub>D</sub>-maltoside could be examined with high sensitivity of every 1-min acquisition. Finally we used polarised TIR-Raman scattering to porcine pancreatic phospholipase A<sub>2</sub> hydrolytic activity on DPPC pslbs and revealed lipid-active conformation different from that of the enzyme alone.
22

Giardia lamblia genomic and molecular analyses of flippase /

Villazana-Kretzer, Diana L. January 2008 (has links)
Thesis (M.S.)--University of Texas at El Paso, 2008. / Title from title screen. Vita. CD-ROM. Includes bibliographical references. Also available online.
23

Modeling the human prothrombinase complex components

Orban, Tivadar. January 2008 (has links)
Thesis (Ph.D.)--Cleveland State University, 2008. / Abstract. Title from PDF t.p. (viewed on Oct. 8, 2008). Includes bibliographical references. Available online via the OhioLINK ETD Center. Also available in print.
24

Investigation of protein-induced formation of lipid domains and their dynamics using fluorescence energy transfer /

Wright, Jenny R. January 2005 (has links) (PDF)
Thesis (M.S.)--University of North Carolina at Wilmington, 2005. / Includes bibliographical references (leaves: 53-55)
25

Applications of the lipidic cubic phase from controlled release and uptake to in meso crystallization of membrane proteins /

Clogston, Jeffrey, January 2005 (has links)
Thesis (Ph.D.)--Ohio State University, 2005. / Title from first page of PDF file. Document formatted into pages; contains xxii, 352 p.; also includes graphics. Includes bibliographical references (p. 346-352). Available online via OhioLINK's ETD Center
26

Gramicidin A and cyclic peptides channel conductances in black lipid membranes

Herasymova, Nataliya January 2010 (has links)
Honors Project--Smith College, Northampton, Mass., 2010. / Includes bibliographical references (p. 102-105).
27

Interaction of pulmonary surfactant protein A (SP-A) with DPPC/egg-PG bilayers /

Abu-Libdeh, Nidal M., January 2003 (has links)
Thesis (M.Sc.)--Memorial University of Newfoundland, 2003. / Bibliography: leaves 60-66.
28

Molecular dynamics simulation of the fully hydrated dipalmitoylphosphatidylcholine (DPPC) bilayer /

Wanasundara, Surajith Nalantha, January 2003 (has links)
Thesis (M.Sc.)--Memorial University of Newfoundland, 2004. / Bibliography: leaves 70-82.
29

Infrared surface plasmons in double stacked nickel microarrays lipid bilayer systems /

Teeters-Kennedy, Shannon Marie, January 2007 (has links)
Thesis (Ph. D.)--Ohio State University, 2007. / Title from first page of PDF file. Includes bibliographical references (p. 278-288).
30

Computational studies of protein-membrane interactions and forced unfolding of proteins /

Krammer, André Thomas. January 2000 (has links)
Thesis (Ph. D.)--University of Washington, 2000. / Vita. Includes bibliographical references (leaves 106-123).

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