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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Identifying the structural determinants of extreme folding and unfolding barriers.

Kelch, Brian A. January 2007 (has links)
Thesis (Ph.D.)--University of California, San Francisco, 2007. / Source: Dissertation Abstracts International, Volume: 68-02, Section: B, page: 0830. Adviser: David A. Agard.
2

Dynamic spatio-temporal interaction of morphogens, forces and growth in embryonic morphogenesis

Zhang, Ying. January 2007 (has links)
Thesis (Ph.D.)--Indiana University, Dept. of Physics, 2007. / Title from dissertation home page (viewed Sept. 29, 2008). Source: Dissertation Abstracts International, Volume: 69-02, Section: B, page: 0881. Adviser: James A. Glazier.
3

Enzymatic and structural studies of the molecular chaperone Hsp90.

Cunningham, Christian Nathaniel. January 2009 (has links)
Thesis (Ph.D.)--University of California, San Francisco, 2009. / Source: Dissertation Abstracts International, Volume: 71-02, Section: B, page: . Adviser: David A. Agard.
4

Function and structure of HIV-1 Rev.

Daugherty, Matthew D. January 2009 (has links)
Thesis (Ph.D.)--University of California, San Francisco, 2009. / Source: Dissertation Abstracts International, Volume: 70-10, Section: B, page: 5988. Adviser: Alan D. Frankel.
5

Heterologous expression of human membrane protein drug targets and the X-ray crystallographic determination of the human aquaporin 4 structure.

Ho, Joseph Daniel. January 2009 (has links)
Thesis (Ph.D.)--University of California, San Francisco, 2009. / Source: Dissertation Abstracts International, Volume: 70-10, Section: B, page: 6049. Adviser: Robert M. Stroud.
6

Expression of Growth Arrest and DNA Damage Protein 45-alpha (gadd45-alpha) and the CCAAT/enhancer binding protein-delta (C/EBP-delta) in Fishes Exposed to Heat and Hypoxia

Hassumani, Daniel O. 23 May 2013 (has links)
<p> The cellular stress response (CSR) is one of the most highly conserved mechanisms among all organisms. Cellular stress can be defined as damage or the threat of damage to proteins, macromolecules and/or DNA. The response to damage can involve cell cycle regulation, protein chaperoning, DNA repair or, if macromolecular damage is too severe, apoptotic mechanisms can be initiated. This thesis details experiments that were designed to examine the cellular response to non-lethal environmental stressors at the protein level, using two fish species as study models. Two proteins that can cause cell cycle arrest and apoptosis mechanisms were examined. Expression of the CCAAT enhancer binding protein-delta (C/EBP-&delta;) was examined in the zebrafish, <i>Danio rerio,</i> exposed to acute, non-lethal hypoxic conditions. While C/EBP-&delta; was expressed constitutively in control individuals during all time points, exposure to hypoxic conditions did not have a consistent significant effect on C/EBP-&delta; expression (two-way ANOVA, P>0.05) in zebrafish white muscle tissue. In a second study, the expression of the growth arrest and DNA damage 45-alpha protein (gadd45-&alpha;), a mediator of cell cycle arrest and perhaps apoptosis was examined in heat-stressed liver tissue of an extremely cold-adapted Antarctic fish, <i>Trematomus bernacchii.</i> Gadd45-&alpha; levels were higher in fish exposure to 2&deg;C across all time points (one-way ANOVA; P&lt;0.05). The findings in these two studies expand our understanding of the CSR and how two genes that are involved in cell cycle regulation respond to acute, non-lethal environmental stress.</p>
7

Studies of the structure and putative complex of the bacterial cell division proteins FtsL, DivIC and DivIB

Robson, Scott Anthony. Unknown Date (has links)
Thesis (Ph. D.)--University of Connecticut, 2006. / (UnM)AAI3221565. Adviser: Glenn King. Source: Dissertation Abstracts International, Volume: 67-06, Section: B, page: 3122.
8

A correspondence between solution-state dynamics of an individual protein and the sequence and conformational diversity of its family: Implications for improving protein design.

Friedland, Gregory D. January 2008 (has links)
Thesis (Ph.D.)--University of California, San Francisco, 2008. / Source: Dissertation Abstracts International, Volume: 69-12, Section: B, page: 7351. Adviser: Tanja Kortemme.
9

Elucidating the mechanism of the ISWI family of chromatin remodeling complexes.

Yang, Janet G. January 2009 (has links)
Thesis (Ph.D.)--University of California, San Francisco, 2009. / Source: Dissertation Abstracts International, Volume: 71-02, Section: B, page: . Adviser: Geeta J. Narlikar.

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