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Biomechanical signals mediate cellular mechano-transduction and gene regulationMadhavan, Shashi D. 10 December 2007 (has links)
No description available.
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Multiple Classifier Strategies for Dynamic Physiological and Biomechanical SignalsNikjoo Soukhtabandani, Mohammad 30 August 2012 (has links)
Access technologies often deal with the classification of several physiological and biomechanical signals. In most previous studies involving access technologies, a single classifier has been trained. Despite reported success of these single classifiers, classification accuracies are often below clinically viable levels. One approach to improve upon the performance of these classifiers is to utilize the state of- the-art multiple classifier systems (MCS).
Because MCS invoke more than one classifier, more information can be exploited from the
signals, potentially leading to higher classification performance than that achievable with single classifiers. Moreover, by decreasing the feature space dimensionality of each classifier, the speed of the system can be increased.
MCSs may combine classifiers on three levels: abstract, rank, or measurement level.
Among them, abstract-level MCSs have been the most widely applied in the literature given the flexibility of the abstract level output, i.e., class labels may be derived from any type of classifier and outputs from multiple classifiers, each designed within a different context, can be easily combined.
In this thesis, we develop two new abstract-level MCSs based on "reputation" values of
individual classifiers: the static reputation-based algorithm (SRB) and the dynamic reputation-based algorithm (DRB). In SRB, each individual classifier is applied to a “validation set”, which is disjoint from training and test sets, to estimate its reputation value. Then, each individual classifier is assigned a weight proportional to its reputation value. Finally, the total decision of the classification system is computed using Bayes rule. We have applied this method to the problem of dysphagia detection in adults with neurogenic swallowing difficulties.
The aim was to discriminate between safe and unsafe swallows. The weighted classification
accuracy exceeded 85% and, because of its high sensitivity, the SRB approach was
deemed suitable for screening purposes. In the next step of this dissertation, I analyzed the SRB algorithm mathematically and examined its asymptotic behavior. Specifically, I contrasted the SRB performance against that of majority voting, the benchmark abstract-level MCS, in the presence of different types of noise.
In the second phase of this thesis, I exploited the idea of the Dirichlet reputation system to develop a new MCS method, the dynamic reputation-based algorithm, which is suitable for the classification of non-stationary signals. In this method, the reputation of each classifier is updated dynamically whenever a new sample is classified. At any point in time, a classifier’s reputation reflects the classifier’s performance on both the validation and the test sets. Therefore, the effect of random high-performance of weak classifiers is appropriately moderated and likewise, the effect of a poorly performing individual classifier is mitigated as its reputation value, and hence overall influence on the final decision is diminished. We applied DRB to the challenging problem of discerning physiological responses from nonverbal
youth with severe disabilities. The promising experimental results encourage further development of reputation-based multi-classifier systems in the domain of access technology research.
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Multiple Classifier Strategies for Dynamic Physiological and Biomechanical SignalsNikjoo Soukhtabandani, Mohammad 30 August 2012 (has links)
Access technologies often deal with the classification of several physiological and biomechanical signals. In most previous studies involving access technologies, a single classifier has been trained. Despite reported success of these single classifiers, classification accuracies are often below clinically viable levels. One approach to improve upon the performance of these classifiers is to utilize the state of- the-art multiple classifier systems (MCS).
Because MCS invoke more than one classifier, more information can be exploited from the
signals, potentially leading to higher classification performance than that achievable with single classifiers. Moreover, by decreasing the feature space dimensionality of each classifier, the speed of the system can be increased.
MCSs may combine classifiers on three levels: abstract, rank, or measurement level.
Among them, abstract-level MCSs have been the most widely applied in the literature given the flexibility of the abstract level output, i.e., class labels may be derived from any type of classifier and outputs from multiple classifiers, each designed within a different context, can be easily combined.
In this thesis, we develop two new abstract-level MCSs based on "reputation" values of
individual classifiers: the static reputation-based algorithm (SRB) and the dynamic reputation-based algorithm (DRB). In SRB, each individual classifier is applied to a “validation set”, which is disjoint from training and test sets, to estimate its reputation value. Then, each individual classifier is assigned a weight proportional to its reputation value. Finally, the total decision of the classification system is computed using Bayes rule. We have applied this method to the problem of dysphagia detection in adults with neurogenic swallowing difficulties.
The aim was to discriminate between safe and unsafe swallows. The weighted classification
accuracy exceeded 85% and, because of its high sensitivity, the SRB approach was
deemed suitable for screening purposes. In the next step of this dissertation, I analyzed the SRB algorithm mathematically and examined its asymptotic behavior. Specifically, I contrasted the SRB performance against that of majority voting, the benchmark abstract-level MCS, in the presence of different types of noise.
In the second phase of this thesis, I exploited the idea of the Dirichlet reputation system to develop a new MCS method, the dynamic reputation-based algorithm, which is suitable for the classification of non-stationary signals. In this method, the reputation of each classifier is updated dynamically whenever a new sample is classified. At any point in time, a classifier’s reputation reflects the classifier’s performance on both the validation and the test sets. Therefore, the effect of random high-performance of weak classifiers is appropriately moderated and likewise, the effect of a poorly performing individual classifier is mitigated as its reputation value, and hence overall influence on the final decision is diminished. We applied DRB to the challenging problem of discerning physiological responses from nonverbal
youth with severe disabilities. The promising experimental results encourage further development of reputation-based multi-classifier systems in the domain of access technology research.
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