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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
11

Bone regenerative response following bone augmentation using hydroxyapatite with and without growth factors

Sohn, Jeong-Yeol. January 1997 (has links)
Thesis (Ph. D.)--Medical College of Georgia, 1997. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.
12

Bone regenerative response following bone augmentation using hydroxyapatite with and without growth factors

Sohn, Jeong-Yeol. January 1997 (has links)
Thesis (Ph. D.)--Medical College of Georgia, 1997. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.
13

Guided bone regeneration of alveolar ridge defects utilizing a Guidor resorbable membrane and bone graft

Kirkland, Virginia M. January 1998 (has links)
Thesis (M.S.)--University of Louisville, 1998. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.
14

Fracture and biochemical markers of bone metabolism

Åkesson, Kristina. January 1995 (has links)
Thesis (Ph. D.)--University of Lund, 1995. / Published dissertation.
15

Guided bone regeneration of alveolar ridge defects utilizing a Guidor resorbable membrane and bone graft

Kirkland, Virginia M. January 1998 (has links)
Thesis (M.S.)--University of Louisville, 1998. / Includes bibliographical references.
16

Fracture and biochemical markers of bone metabolism

Åkesson, Kristina. January 1995 (has links)
Thesis (Ph. D.)--University of Lund, 1995. / Published dissertation.
17

Recombinant adenovirus and adeno-associated virus mediated BMP2 and BMP4 gene therapy for new bone formation

Chen, Yan, 陳岩 January 2003 (has links)
published_or_final_version / Orthopaedic Surgery / Doctoral / Doctor of Philosophy
18

An in vitro study of the effect of silicon and magnesium ions on bone repair and angiogenesis

Robertson, Zoe January 2009 (has links)
The addition of silicon ions (10-500 μM) to the culture medium of MG63 osteoblast-like cells showed no changes in cell viability, metabolic activity, proliferation or morphology. Silicon ions resulted in a concentration-dependent increase in the expression of vascular endothelial growth factor (VEGF) by the MG63 cells. Addition of magnesium ions (1-50 mM) to the culture medium of MG63 cells caused a dose-dependent decrease in cell viability, metabolic activity and proliferation at each time point. In general, silicon and magnesium ions had no effect on the viability of a human endothelial cell line (HUVEC). A slight decreasing trend to the metabolic activity of the HUVECs was observed with increasing concentrations of silicon ions at all time points, but this decreasing trend was more pronounced with the addition of magnesium ions. The highest magnesium ion concentration studied (50 mM) caused a change in HUVEC morphology from a typical cobblestone appearance to a fibroblast-like shape. Lastly, the effect of silicon ions on angiogenesis <i>in vitro</i> was studied using two different <i>in vitro</i> assays. The first, using Matrigel as an extracellular matrix coating for the guidance of endothelial cells to form tube-like structures (an indicator of angiogenesis), proved unreliable for studying the promotion of angiogenesis. Additionally, tube-like structures were also observed with osteoblasts cells, raising questions about the efficiency of this assay. The second assay, AngioKit, was a suitable model for studying stimulation and inhibition of tube-like formation. Results obtained using this assay showed that silicon ions alone (500 μM) did not stimulate tube-like formation, but a significant increase in tube-like formation was observed with MG63 cell-conditioned media, with (500 μM) and without silicon ions, when compared to the control medium.
19

Composite Hydrogel Scaffolds with Eggshell Particles as a Novel Bone Regeneration Material

Calvert, Nick 29 July 2019 (has links)
The development of bone regeneration materials to support new bone formation is an active field of research. This report describes the development and characterization of a novel composite scaffold made of a chitosan-alginate co-polymer hydrogel matrix and eggshell (ES) particles. Scaffolds with ES particles or with nanotextured ES (NTES) particles following treatment with phosphoric acid were compared to scaffolds without particles. The scaffolds with particles exhibited a higher porosity and a larger median pore size. Their mechanical strength remained low, but both scaffold types were more resistant to deformation following compression than the scaffolds without particles. The osteogenic potential of the scaffolds was then evaluated with human bone-marrow derived mesenchymal stem cells (MSCs) from four different donors. Results showed that the inclusion of ES or NTES particles significantly increased MSC adherence and viability, as well as alkaline phosphatase activity in the scaffolds. A change of cell morphology and a small, although not statistically significant, increase of osteogenic protein expression (RUNX2 and osteopontin) were also observed at later time points (days 14 and 21). Overall, this research highlights the potential of ES for bone regeneration applications, opening the door for a high-value repurposing of a current industrial waste product.
20

Impact of collagen type X deficiency on bone fracture healing

Kaluarachchi, Thambilipitiyage Kusumsiri Priyantha Kumara. January 2001 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2001. / Includes bibliographical references (leaves 179-213).

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