In spite of vigorous research efforts to date the induction of bone formation by macroporous coral-derived constructs when implanted heterotopically in the rectus abdominis muscle of the non-human primate Chacma baboon Papio ursinus has not yet been resolved and needs to be assigned. More importantly, the apparent redundancy of molecular signals singly initiating the induction of bone formation in primate species and the heterotopic induction of endochondral bone formation by the mammalian recombinant human transforming growth factor –β3 (rhTGF-β3) isoform have not yet been assigned and need to be mechanistically resolved. Using the rectus abdominis muscle of Papio ursinus the study sought to molecularly determine how coral-derived macroporous constructs and doses of the hTGF-β3 isoform initiate the induction of bone formation. To elucidate the function of osteoclastogenesis and Ca2+, biomimetic coral-derived 7% hydroxyapatite/calcium carbonate (7% HA/CC) devices were supplemented either with 240 μg zoledronate bisphosphonate, an osteoclast binding antagonist, or 500 μg of the calcium channel blocker verapamil hydrochloride. Additionally but in separate coralderived bioreactors, 125 μg rhTGF-β3 and/or 125 μg hNoggin were added to answer the question of how TGF-β3 induces bone formation. All devices were then subsequently implanted within heterotopic sites of the rectus abdominis muscle of 6 Papio ursinus and left in vivo for 15, 60 and 90 days. Harvested specimens were subjected to histomorphometrical and quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis. Collagen Type IV expression supported by extensive vascularisation was detected and observed respectively in all implants after 15 days in vivo. Importantly the zoledronate treated specimens possessed delayed tissue patterning and morphogenesis,

林詠嫦. / 手稿本(copies 2 & 3 複印本) / Thesis (M.A.)--香港中文大學硏究院中國語文學部. / Shou gao ben(copies 2 & 3 fu yin ben) / Lin Yongchang. / Thesis (M.A.)--Xianggang Zhong wen da xue yan jiu yuan Zhongguo yu wen xue bu. / 前言 / Chapter 第一章 --- 「□組卜辭」的內容和範圍启 / Chapter 第一節 --- 「□組卜辭」名目的由來及其基本內容 --- p.1 / Chapter 第二節 --- 「王族」貞人與一期貞人的系聯問題 --- p.14 / Chapter 第三節 --- 貞人「甾」與「□組」的關係 --- p.28 / Chapter 第四節 --- 本章總結 --- p.35 / Chapter 第二章 --- 「□組卜辭」的特徵 / Chapter 第一節 --- 稱謂 --- p.47 / Chapter 第二節 --- 字體現象 --- p.65 / Chapter 第三節 --- 文例 --- p.79 / Chapter 第四節 --- 曆法´ؤ´ؤ置閏法 --- p.116 / Chapter 第五節 --- 事類 --- p.134 / Chapter 第五節 --- 本章總結 --- p.142 / Chapter 第三章 --- 各家學說的概述及評折 / Chapter 第一節 --- 董作賓先生的「文武丁卜辭」說 --- p.155 / Chapter 第二節 --- 貝塚茂樹先生的「占卜機構」說 --- p.201 / Chapter 第三節 --- 陳夢家先生的「武丁晚期」說 --- p.249 / Chapter 第四節 --- 林澐先生的「大小字羣」說 --- p.264 / Chapter 第五節 --- 本章總結 --- p.308 / Chapter 第四章 --- 兩項可供斷代參攷的證據──地層和占辭現象 / Chapter 第一節 --- 一九七三年小屯南地發掘提共的地層證據 --- p.336 / Chapter 第二節 --- 從占辭現象探索「□組卜辭」的性質 --- p.365 / Chapter 第三節 --- 本章總結 --- p.393 / Chapter 第五章 --- 結論 --- p.400 / 附錄 / 引書簡稱表 --- p.1 / 參攷書目 --- p.6

手稿本. / Thesis (M.A.)--香港中文大學. / Shou gao ben. / Thesis (M.A.)--Xianggang Zhong wen da xue. / 一畫 / 一人 --- p.1 / 一卜 --- p.9 / 一月 --- p.12 / 一宗 --- p.23 / 一宗上甲 --- p.24 / 乙門 --- p.29 / 二畫 / 二云 --- p.34 / 十三月 --- p.37 / 三畫 / 三云(雲) --- p.60 / 三嗇云(雲) --- p.61 / 亡延 --- p.66 / 亡其告麥 --- p.71 / 亡其來齒 --- p.72 / 亡來齒 --- p.73 / 下歲 --- p.74 / 四畫 / 不矢眾 --- p.76 / 不雉眾 --- p.79 / 不喪眾 --- p.81 / 不喪明 --- p.82 / 不延雨 --- p.83 / 不其延雨 --- p.84 / 不延 --- p.85 / 不□雨 --- p.87 / 勿延 --- p.91 / 不齒 --- p.93 / 不其來見王 --- p.94 / 不其氐龜 --- p.95 / 及雨 --- p.96 / 元卜 --- p.98 / 元臣 --- p.100 / 元示 --- p.102 / 元□反 --- p.112 / 今來 --- p.113 / 今來歲 --- p.115 / 今生 --- p.118 / 今生月(看今生) --- p.118 / 今生一月(看今生) --- p.118 / 允亡 --- p.123 / 允□告麥 --- p.125 / 允□來齒 --- p.126 / 允□來入齒 --- p.127 / □告麥 --- p.128 / □來自南氐龜 --- p.134 / 王人 --- p.135 / 王□(師) --- p.137 / 王眾 --- p.139 / 王族 --- p.141 / 王□曰 --- p.149 / 六云(雲) --- p.153 / 五畫 / 四云(雲) --- p.155 / □羌(以羌) --- p.156 / 弗雉王眾 --- p.157 / 正月 --- p.158 / 示元 --- p.161 / 氐牛 --- p.164 / 氐羌 --- p.167 / 氐馬 --- p.168 / 氐齒 --- p.169 / 氐龜 --- p.171 / 生月 --- p.182 / 以：看□ / 六畫 / 西母 --- p.194 / 有：看□ / 七畫 / 余一人 --- p.195 / 告秋 --- p.203 / 告歲 --- p.207 / 延雨 --- p.208 / 延風 --- p.215 / □：看延 / □：看延 / 八畫 / 其延雨 --- p.221 / 其延 --- p.222 / 其□雨 --- p.227 / 其來見王 --- p.228 / 其□來齒 --- p.229 / 其氐齒 --- p.237 / 其齒 --- p.238 / 其喪眾 --- p.241 / 其喪人 --- p.246 / 其喪明 --- p.248 / 東母 --- p.250 / 來王 --- p.255 / 來牛 --- p.259 / 來羌 --- p.261 / 來馬 --- p.268 / 來象 --- p.270 / 九畫 / 帝云 --- p.272 / 茲云 --- p.291 / 屎□足 --- p.294 / 十一畫 / 習一卜 --- p.298 / 習二卜 --- p.299 / 習三卜 --- p.300 / 習四卜 --- p.301 / 習龜卜 --- p.302 / 習□卜 --- p.319 / 十二畫 / 眾人 --- p.322 / 喪眾人 --- p.354 / 喪□(師) --- p.356 / 喪□(命) --- p.360 / 奠血 --- p.363 / 黃呂 --- p.366 / 十三畫 / 雉眾 --- p.372 / 十六畫 / 龜氐 --- p.393 / 龜不其南氐 --- p.394 / 廿七畫 / 鑽三骨三□(殼) --- p.395 / 鑽三□骨三 --- p.409 / 主要參考書目

李達良著. / 書名據卷端 / 稿本 / 論文(碩士)--香港中文大學硏究院,1968. / 參考文獻: leaves 387-391 / Li Daliang zhu. / Chapter 0 --- 前言 / Chapter 甲 --- 方位篇 / Chapter 子 --- 卜龜概說 / Chapter 一 --- 龜版之攻治及其自然結構 / Chapter 二 --- 占卜有關人物之職掌 / Chapter 三 --- 占卜之技術程序及兆、數、辭三者之關係 / Chapter 丑 --- 刻辭位置及先後次序釋例 / Chapter 第一式 --- （每式有簡圖） / Chapter 第二式 / Chapter 第三式 / Chapter 第四式 / Chapter 第五式 / Chapter 第六式 / Chapter 第七式 / Chapter 第八式 / Chapter 第九式 / Chapter 第十式 / Chapter 寅 --- 刻辭行文方向釋例 / Chapter A --- 正例（每例前有簡圖） / 右邊 / Chapter 一 --- 起邊緣者向內下行而左例 / Chapter 二 --- 起中縫及近中部位置者向外下行而右例 / Chapter 三 --- 起於內連甲橋用者向下行而右例 / 左邊 / Chapter 一 --- 起邊緣者向內下行而右例 / Chapter 二 --- 起中縫及近中部位置者向外下行而左例 / Chapter 三 --- 起於內連甲橋用者向外下行而左例 / Chapter B --- 變例（每例前有簡圖） / Chapter 一 --- 直行例 / Chapter 二 --- 橫行例 / Chapter 卯 --- 同組刻辭位置釋例 / Chapter A --- 整版（每例前有簡圖） / Chapter 一 --- 左右平行相對例 / Chapter 二 --- 左右斜向相對例 / Chapter 三 --- 三角相對例 / Chapter 四 --- 三辭平行相對例 / Chapter 五 --- 三解斜向相對例 / Chapter B --- 半邊 / Chapter 一 --- 左右相對例 / Chapter 二 --- 上下相對例 / Chapter 三 --- 斜向相對例 / Chapter 四 --- 三角相對例 / Chapter 五 --- 三辭斜向相對例 / Chapter 辰 --- 正向刻辭與背面相承釋例 / Chapter 一 --- 一組對貞分刻于正背面例 / Chapter 二 --- 同屬卜問一事之辭分刻于正背例 / Chapter 三 --- ℗¡驗之辭刻于背例 / Chapter 四 --- 卜日貞人刻于背例 / Chapter 五 --- 卜曰貞人与℗驗之辭皆刻于背例 / Chapter 乙 --- 文例篇 / Chapter 已 --- 卜辭種類釋例 / Chapter A --- 單貞 / Chapter 一 --- 單貞正問例 / Chapter 二 --- 單貞負問例 / Chapter B --- 對貞 / Chapter 一 --- 對貞正在右負在左例 / Chapter 二 --- 對貞正在左負在右例 / Chapter 三 --- 二辭正例 / Chapter 四 --- 二辭皆負例 / Chapter C --- 同卜一事刻數辭所問不限于正負之辭 / Chapter 一 --- 同一祭主卜問用牲之數或牲類不同例 / Chapter 甲 --- 刻二辭者 / Chapter 乙 --- 刻二辭以上者 / Chapter 二 --- 同卜一事所問對象不同例 / Chapter 甲 --- 刻二辭者 / Chapter 乙 --- 刻二辭以上者 / Chapter 三 --- 所卜事同進行及發生之時日不同或程序有先後之異或人地名舉于後刻之辭例 / Chapter 甲 --- 刻二辭者 / Chapter 乙 --- 刻二辭以上者 / Chapter D --- 成套卜辭 / Chapter 一 --- 一正一負例 / Chapter 二 --- 數辭皆正例 / Chapter E --- 同事多卜刻二辭以上，體例与成套卜辭同而序數不相連之辭 / Chapter 一 --- 一正一負例 / Chapter 二 --- 二正一負例 / Chapter 三 --- 二負一正例 / Chapter 午 --- 卜辭段落結構釋例 / Chapter A --- 四段 / Chapter 一 --- 四段俱全例 / Chapter B --- 三段 / Chapter 一 --- 前辭命辭o 辭例 / Chapter 二 --- 前辭命辭驗辭合刻例 / Chapter 三 --- 命辭o辭驗辭合刻例 / Chapter C --- 二段 / Chapter 一 --- 前辭命辭合刻例 / Chapter 二 --- 命辭o辭合刻例 / Chapter 三 --- 命辭驗辭合刻例 / Chapter D --- 一段 / Chapter 一 --- 僅刻命辭例 / Chapter 未 --- 前辭釋例 / Chapter 一 --- 某日卜某貞例 / Chapter 二 --- 某日卜某無貞字例 / Chapter 三 --- 某日卜例 / Chapter 四 --- 某日卜貞例 / Chapter 五 --- 僅記貞字例 / Chapter 六 --- 某日卜王例 / Chapter 七 --- 稱曰例 / Chapter 辛 --- 卜辭省文釋例 / Chapter 一 --- 二辭相對省文例 / Chapter 甲 --- 省卜日及貞人 / Chapter 乙 --- 省前辭 / Chapter 丙 --- 省貞字 / Chapter 丁 --- 正面不記卡曰貞人及面省貞字 / Chapter 戊 --- 省命辭之文 / Chapter 二 --- 二辭以上相對省文例 / Chapter 甲 --- 省前辭之文 / Chapter 乙 --- 省前辭及命辭之文 / Chapter 三 --- 不同事類之相對省文例 / Chapter 0 --- 省前辭之文 / Chapter 四 --- 成套卜辭省文例 / Chapter 甲 --- 省前辭之文 / Chapter 乙 --- 省前辭及命辭之文 / Chapter 五 --- 成套腹甲省文例 / Chapter 0 --- 附錄 / Chapter 0 --- 引用書目

Bone diseases such as osteoporosis and rickets cause significant reduction in bone quantity and quality, leading to mechanical abnormalities. While the reduction of bone quantity can be assessed using clinical tools like DXA and pQCT, there is little quantitative knowledge of how altered bone quality in diseased bone increases fracture risk. There is a clear need to develop high-resolution diagnostic techniques to close the gap between onset of fracture relevant changes and diagnosis. Here, a functional imaging technique (in situ synchrotron X-ray imaging with micromechanics) was developed to measure alterations in fibrillar deformation mechanisms in rickets, glucocorticoid-induced osteoporosis (GIOP), and premature ageing. During applied loading, percentage shifts in Bragg peak positions arising from the meridional collagen stagger, measured from the small angle X-ray scattering (SAXS) patterns, give fibrillar level strain as a function of applied stress in real time. To link nanostructural changes to altered fracture risk and deformability, well defined animal (mouse) models created via N-ethylnitrosurea mutagenesis were used. The fibril modulus, maximum fibril strain and fibril-to-tissue strain ratio were determined, complemented by quantitative backscattered scanning electron microscopy and microcomputed tomography to measure microscale mineralisation. A significant reduction of fibril modulus and enhancement of maximum fibril strain was found in rickets and GIOP mice. A significantly larger fibril strain/tissue strain ratio was found in GIOP mice compared to wild-type mice, indicative of a lowered mechanical competence at the bone matrix level. The effects of altered in vivo muscular force distributions on the skeletal system in rickets were measured using position resolved scanning SAXS. Increase of mineral nanoplatelet alignment is observed in wild-type mice near zones of large in-vivo muscle force but not in rachitic mice. These results demonstrate the ability of synchrotron-based in situ X-ray nanomechanical imaging to identify functional alterations in nanoscale bone quality in metabolic bone diseases.

Master of Dental Surgery / This work was digitised and made available on open access by the University of Sydney, Faculty of Dentistry and Sydney eScholarship . It may only be used for the purposes of research and study. Where possible, the Faculty will try to notify the author of this work. If you have any inquiries or issues regarding this work being made available please contact the Sydney eScholarship Repository Coordinator - ses@library.usyd.edu.au

The morphology and function of the wrist is poorly understood. Improved understanding of carpal anatomy may facilitate improved understanding of carpal mechanics and may enhance the clinical management of wrist dysfunction. Many detailed investigations of wrist structure have been reported, many of which have focussed on the scaphoid and its ligamentous supports. The results of these studies are not readily collated to provide an accurate description of the scaphoid and its supports. This study attempted to provide a detailed description of the anatomy of the scaphoid and its supporting structures. A detailed nomenclature was proposed to facilitate accurate description of the scaphoid and related structures. Gross observation enabled separation of the sample population of scaphoids into two groups. Morphometric analyses were used to determine any significant differences between the groups (type one and type two). The histological sections were then used to facilitate accurate gross identification of ligaments and computed tomographs were used to investigate the in situ variation of scaphoid orientation. The investigations suggest that two distinct populations of scaphoid existed within the sample population. The scaphoids varied in bone morphology, arrangement and degree of ligamentous support and position relative to the capitate. Articular facet shape and size differed between scaphoid types. The orientation and number of ligaments supporting the scaphoid were suggestive of variable scaphoid motion. The variation in ligamentous patterns was supported by histological investigation. Computed tomographs through the longitudinal axis of the scaphoid suggested a variable position of the scaphoid relative to the capitate. The variation of these structures was discussed in relation to the kinematic findings of others. A theoretical model of variable scaphoid function was proposed based on the anatomical findings. The data presented and the reviewed kinematic data may be extrapolated to suggest two models of scaphoid motion. The scaphoids may be divided into rotating/translating scaphoids and flexing/extending scaphoids. This must be confirmed by a combined anatomical and mechanical study. The clinical implications of different scaphoid structure and function may be profound. The ability to identify such differences in situ may facilitate varied clinical management for the various types of wrist suggested. / Thesis (Ph.D.)--Department of Anatomical Sciences, 2004.

"February 2005" / Coursework / Bibliography: leaves 212-222. / 222 leaves : / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / "Distraction osteogenesis is a surgical technique employed for bone lengthening and reconstruction of skeletal deformities. It is a biological process of new bone formation between bone segments gradually separated by incremental traction". "The purpose of this research was to conduct a pilot study to determine whether immersion fixation is adequate for evaluation of BMP-2, VEGF, Type X collagen expression in a sheep model using immunohistochemical techniques, and to evaluate the expression of these factors during the different stages of distraction osteogenesis." --leaf 14. / Thesis (D.Clin.Dent.)--University of Adelaide, Dental School (Orthodontics), 2005

Typescript (photocopy) / 214 leaves, [80] leaves of plates : / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (M.D.)--University of Adelaide, Dept. of Surgery, 1982

Thesis (Ph.D.)--University of Delaware, 2007. / Principal faculty advisor: Daniel D. Carson, Dept. of Biological Sciences. Includes bibliographical references.