No description available.

No description available.

Thesis (Ph. D.)--University of Texas at Austin, 2007. / Vita. Includes bibliographical references.

The objective of this study is the preparation of a tetracycline-boron-10 derivative which is stable under biological conditions. The boron-10 should then provide a concentration of material capable of accepting thermal neutrons, thus producing localized high-energy alpha radiation. The fact that the tetracyclines are not retained by normal tissue should remove the danger of destruction of this tissue.

Thesis (doctoral)--Lund University, 1994. / Added t.p. with thesis statement inserted.

Thesis (doctoral)--Lund University, 1994. / Added t.p. with thesis statement inserted.

by Ong Chung Wo. / Title also in Chinese. / Thesis (Ph.D.)--Chinese University of Hong Kong. / Bibliography: leaves 258-263. / Acknowledgements / Abstract / Table of Contents / Chapter Chapter 1 --- Introduction --- p.1 / Chapter Chapter 2 --- Sample Preparation --- p.6 / Chapter A. --- General Review of Chemical Vapour Deposition Technique --- p.6 / Chapter B. --- Our Deposition System --- p.9 / Chapter B.1 --- General Description --- p.9 / Chapter B.2 --- Induction Heater --- p.10 / Chapter B.3 --- Graphite Susceptor --- p.12 / Chapter B.4 --- Safety --- p.13 / Chapter C. --- Sample Description --- p.16 / Chapter Chapter 3 --- Thickness Measurement --- p.26 / Chapter Chapter 4 --- Composition Analysis --- p.29 / Chapter A. --- Introduction --- p.29 / Chapter B. --- Composition Analysis of Boron-Silicon Films Using EDX --- p.32 / Chapter B.1 --- Experimental Method --- p.32 / Chapter B.2 --- Requirement on Film Thickness and Preparation of Unsupported Films --- p.33 / Chapter B.3 --- Possible Applications and Limitations of Our Method --- p.35 / Chapter B.4 --- Results --- p.35 / Chapter Chapter 5 --- X-ray Diffraction Experiment --- p.42 / Chapter A. --- Introduction --- p.42 / Chapter B. --- Structures of Boron and Silicon-Boron Compounds --- p.43 / Chapter B.1 --- B12 Icosahedron and Three-Center Two-Electron Bond --- p.43 / Chapter B.2 --- Polymorphism of Crystalline Boron --- p.44 / Chapter B.2.1 --- α-Rhombohedral Boron --- p.44 / Chapter B.2.2 --- β-Rhombohedral Boron --- p.45 / Chapter B.2.3 --- Amorphous Boron --- p.47 / Chapter B.3 --- Structures of Crystalline Boron-Silicon Compounds --- p.48 / Chapter C. --- X-ray Diffraction Experiment --- p.50 / Chapter C.1 --- Experimental Technique --- p.50 / Chapter C.2 --- Analysis of X-Ray Diffraction Pattern --- p.50 / Chapter D. --- Results and Discussion --- p.51 / Chapter D.1 --- Boron Films --- p.51 / Chapter D.2 --- Boron-Silicon Films --- p.57 / Chapter Chapter 6 --- Infrared Absorption Experiment --- p.84 / Chapter A. --- Experimental Method --- p.84 / Chapter B. --- Results --- p.87 / Chapter C. --- Discussion --- p.88 / Chapter C.1 --- Analysis of Boron Films --- p.88 / Chapter C.1.1 --- Indentification of Three Absorption Bands --- p.88 / Chapter C.1.2 --- Effect of Substrate Temperature --- p.91 / Chapter C.2 --- Analysis of Boron-Silicon Films --- p.92 / Chapter C.2.1 --- Effect of Substrate Temperature --- p.92 / Chapter C.2.2 --- Effect of Silicon Incorporation --- p.93 / Chapter C.2.3 --- Existence of Icosahedral Clusters --- p.94 / Chapter C.3 --- Comparative Study of Deposition Mechanism Between Thermal CVD Method and Glow Discharge Method --- p.94 / Chapter Chapter 7 --- Microhardness and Surface Morphology --- p.111 / Chapter A. --- Measuring Techniques --- p.111 / Chapter B. --- Microhardness Measurement --- p.113 / Chapter B.1 --- Boron Films --- p.113 / Chapter B.2 --- Boron-Silicon Films --- p.114 / Chapter C. --- Surface Morphology --- p.114 / Chapter C.1 --- Boron Films --- p.114 / Chapter C.2 --- Boron-Silicon Films --- p.115 / Chapter Chapter 8 --- Optical Absorption Experiment --- p.127 / Chapter A. --- Introduction --- p.127 / Chapter B. --- Theory of Optical Absorption --- p.128 / Chapter B.1 --- Absorption of Crystalline Materials --- p.129 / Chapter B.2 --- Optical Absorption of Amorphous Materials --- p.132 / Chapter C. --- Results --- p.135 / Chapter C.1 --- Boron Films --- p.135 / Chapter C.2 --- Boron-Silicon Films --- p.136 / Chapter D. --- Analysis --- p.138 / Chapter D.1 --- Band Models --- p.138 / Chapter D.2 --- Deconvolution of Absorption Spectra --- p.140 / Chapter D.2.1 --- Deconvolution of Absorption Spectra of Boron Films --- p.141 / Chapter D.2.2 --- Deconvolution of Absorption Spectra of Boron-Silicon Films --- p.144 / Chapter D.2.3 --- Results --- p.146 / Chapter E. --- Discussion --- p.149 / Chapter Chapter 9 --- Conductivity and Thermoelectric Power Measurements --- p.203 / Chapter A. --- Transport Mechanism in Amorphous Semiconductors --- p.203 / Chapter A.1 --- Band Models of Amorphous Semiconductors --- p.203 / Chapter A.2 --- Electrical Conductivity and Thermoelectric Power --- p.205 / Chapter B. --- Experimental Methods --- p.208 / Chapter C. --- Results --- p.209 / Chapter C.1 --- Boron Films --- p.209 / Chapter C.2 --- Boron-Silicon Films --- p.210 / Chapter D. --- Discussion --- p.212 / Chapter D.1 --- Boron Films --- p.212 / Chapter D.2 --- Boron-Silicon Films --- p.213 / Chapter Chapter 10 --- Electron Spin Resonance --- p.230 / Chapter A. --- Introduction --- p.230 / Chapter B. --- Experimental Method --- p.231 / Chapter C. --- Results --- p.231 / Chapter C.1 --- Boron Films --- p.231 / Chapter C.2 --- Boron-Silicon Deposited at 300°C --- p.232 / Chapter C.3 --- Boron-Silicon Deposited at 460 and 620°C --- p.233 / Chapter D. --- Discussion --- p.235 / Chapter D.1 --- Boron Films --- p.235 / Chapter D.2 --- Boron-Silicon Films --- p.237 / Chapter Chapter 11 --- Conclusion --- p.254 / Chapter A. --- Structure --- p.254 / Chapter B. --- Mechanical Properties --- p.256 / Chapter C. --- Optical Absorption and Density of States --- p.256 / Chapter D. --- Electrical Properties --- p.257 / References --- p.258

1H and 13C{1H} NMR spectra of all the new compounds and crystallographic data are given in the Appendix. / Chapter 1 presents an overview of phthalocyanines including their general synthesis, properties, and applications. Special attention has been placed on the unsymmetrical analogues, and those which are efficient photosensitizers in photodynamic therapy. A brief account on BODIPYs as another versatile class of functional dyes is also given. / Chapter 2 describes the synthesis, spectroscopic characterization, photophysical properties, and in vitro photodynamic activities of three novel amphiphilic zinc(II) phthalocyanines substituted with one or two 3,4,5-tris(3,6,9-trioxadecoxy)benzoxy group(s). These compounds exhibit significantly higher photodynamic activities toward HepG2 and HT29 cell lines. The alpha-substituted analogue is particularly potent with IC50 values as low as 0.02 microM. The higher photodynamic activity of this compound can be attributed to its lower aggregation tendency in the culture media as shown by absorption spectroscopy and higher cellular uptake as suggested by the stronger intracellular fluorescence, resulting in a higher efficiency to generate reactive oxygen species inside the cells. / Chapter 4 focuses on a related series of 1,4-disubstituted zinc(II) phthalocyanines. These compounds possess two oligoethylene glycol methyl ether chains with various length at the 1,4-di-alpha-positions. The effects of the chain length on their aggregation, photophysical properties, cellular uptake, and in vitro photodynamic activities have been explored. / Chapter 5 presents the synthesis, characterization, and photophysical properties of another series of zinc(II) phthalocyanines conjugated with one, two or four isopropylidene protected glucofuranose unit(s) through a tetraethylene glycol linker. With these hydrophilic substituents, these macrocycles are highly soluble in common organic solvents and biological media. Their in vitro photodynamic activities toward HT29 and HepG2 cells have also been evaluated. Compared with the tetra-glucosylated phthalocyanines, which are almost nonphotocytotoxic, the mono- and di-glucosylated analogues exhibit a higher photodynamic activity. The di-alpha-substituted analogue is particularly potent with IC50 values as low as 0.03 microM. / Chapter 6 reports the synthesis, characterization, and photophysical properties of two novel conjugates of subphthalocyanine substituted axially with a BODIPY or distyryl-BODIPY moiety. Both systems absorb over a broad range in the visible region. They also exhibit a highly efficient photo-induced energy transfer process either from the excited BODIPY to the subphthalocyanine core or from the excited subphthalocyanine to the distyryl-BODIPY unit. The energy transfer quantum yields are close to unity for both of these conjugates. / Chapter 7 describes the preparation and photophysical properties of another two BODIPY and monostyryl-BODIPY conjugates which are linked to a silicon(IV) phthalocyanine core. These conjugates serve as excellent artificial photosynthetic models for the study of energy and electron transfer processes. Depending on the axial substituents, these conjugates exhibit predominantly a photo-induced energy or electron transfer process in toluene. / The related studies of a series of novel di-alpha-substituted zinc(II) phthalocyanines having two biocompatible triethylene glycol methyl ether chains or glycerol moieties are described in Chapter 3. Compared with the unsubstituted analogue, these compounds have a red-shifted Q band, and exhibit a relatively weaker fluorescence emission and higher efficiency to generate singlet oxygen. As a result, these compounds are promising candidates for photodynamic therapy. In vitro studies on HepG2 and HT29 cells have shown that they are highly photocytotoxic with IC50 values as low as 0.06 microM. / This thesis describes my synthetic studies on several series of functional zinc(II) phthalocyanines and boron dipyrromethenes (BODIPYs). Their applications as efficient photosensitizers in photodynamic therapy and light harvesting systems have also been explored. / Liu, Jianyong. / Adviser: Dennis Keepui Ng. / Source: Dissertation Abstracts International, Volume: 71-01, Section: B, page: 0326. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2009. / Includes bibliographical references. / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. Ann Arbor, MI : ProQuest Information and Learning Company, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstracts in English and Chinese.

Ho, Yuk Ting. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2007. / Includes bibliographical references. / Abstracts in English and Chinese. / Acknowledgement --- p.i / Abstract --- p.vi / Chapter Chapter 1 --- Introduction --- p.1 / Chapter 1.1 --- Composite Materials --- p.1 / Chapter 1.2 --- General Properties of Composite Materials --- p.2 / Chapter 1.3 --- Fabrication of Composite Materials --- p.3 / Chapter 1.3.1 --- Liquid State Sintering --- p.4 / Chapter 1.3.2 --- Casting --- p.6 / Chapter 1.3.3 --- Other Fabrication Techniques --- p.7 / Chapter 1.4 --- Phase Transformation --- p.8 / Chapter 1.5 --- Nucleation and Growth --- p.10 / Chapter 1.5.1 --- Homogeneous nucleation --- p.10 / Chapter 1.5.2 --- Heterogeneous nucleation --- p.10 / Chapter 1.5.3 --- Growth --- p.11 / Chapter 1.6 --- Phase Separation by Spinodal Decomposition --- p.11 / Chapter 1.6.1 --- The Initiation of Spinodal Decomposition --- p.12 / Chapter 1.6.2 --- Dynamics of Spinodal Decomposition --- p.12 / Chapter 1.6.3 --- Difference between Coherent Spinodal and Nucleation and Growth --- p.17 / Chapter 1.7 --- Methods in Obtaining Large Under-cooling --- p.19 / References --- p.20 / Figures --- p.23 / Chapter Chapter 2 --- Experiment --- p.29 / Chapter 2.1 --- Introduction --- p.29 / Chapter 2.2 --- Preparation of Fused Silica Tubes --- p.29 / Chapter 2.3 --- Sample Preparation --- p.30 / Chapter 2.3.1 --- Alloying --- p.30 / Chapter 2.3.2 --- Fluxing --- p.30 / Chapter 2.3.3 --- Under-cooling --- p.31 / Chapter 2.4 --- Microstructure Analysis --- p.32 / Chapter 2.4.1 --- Sample Surface Analysis --- p.32 / Chapter 2.4.2 --- Scanning Electron Microscopy (SEM) --- p.32 / Chapter 2.5 --- Transmission Electron Microscopy (TEM) --- p.32 / Chapter 2.5.1 --- Specimen Requirement --- p.33 / Chapter 2.5.2 --- "Cutting, Grinding, Polishing and Pouching" --- p.33 / Chapter 2.5.3 --- Dimpling --- p.34 / Chapter 2.5.4 --- Ion Milling --- p.34 / Chapter 2.5.5 --- Microstructure Characterization by TEM --- p.35 / Chapter 2.6 --- Mechanical Properties --- p.37 / Chapter 2.6.1 --- Hardness Testing --- p.37 / Chapter 2.6.2 --- Compression Testing --- p.37 / Chapter 2.7 --- Characterizations of Untreated Samples --- p.38 / References --- p.39 / Figures --- p.40 / Chapter Chapter 3 --- Formation and Properties of Co-Si-B Metal Matrix Composites --- p.44 / Abstract --- p.44 / Introduction --- p.45 / Experimental --- p.46 / Results --- p.47 / Chapter A. --- Microstructures --- p.48 / Eutectic Co75Si15B10 --- p.48 / Network Co75Si15B10 --- p.48 / Chapter B. --- Mechanical Behavior --- p.50 / Eutectic Co75Si15B10 --- p.50 / Network CO75Si15B10 --- p.51 / Discussions --- p.53 / Conclusion --- p.53 / Acknowledgement --- p.54 / References --- p.55 / Figures --- p.56 / Chapter Chapter 4 --- On the Network Morphology of Co75Si15B10 Alloys --- p.68 / Abstract --- p.68 / Introduction --- p.69 / Experimental --- p.69 / Results --- p.69 / Discussions --- p.74 / Acknowledgement --- p.77 / References --- p.78 / Figures --- p.79 / Chapter Chapter 5 --- Conclusion --- p.100

Thesis (Ph. D.)--Florida State University, 2004. / Advisor: Dr. William G. Moulton, Florida State University, College of Arts and Sciences, Dept. of Physics. Title and description from dissertation home page (viewed June 15, 2004). Includes bibliographical references.