Geodetic models suggest that much of the convergence across the Himalaya (~20 mm yr-1) is taken up on the Main Himalayan Thrust, the main decollement beneath the Himalayan orogenic wedge. In Central Nepal and the majority of Northwest India, several geomorphic, geophysical and seismological datasets indicate that this decollement has a mid-crustal ramp that continues uninterrupted for hundreds of kilometers along strike from Nepal in the east to Uttarakhand in the west. In this study, I use spatial analyses of elevation, relief, channel steepness indices, and basin-wide erosion rates from cosmogenic 10-Be concentrations to outline a potential large-scale change in the active fault configuration between the Main Himalayan Thrust and Main Boundary Thrust near longitude 77°E in the Northwestern Indian Himalaya. The physiography in the areas to the east of 77ºE appears similar to that observed along much of the Himalaya where topographic relief, erosion rates, and river channel steepness (ksn <200) remain relatively low in the areas to the south of a line known as the Physiographic Transition-2. North of the Physiographic Transition-2, these metrics increase sharply within a 30-km zone due to higher rock uplift rates above a mid-crustal ramp on the decollement or an unidentified out-of-sequence thrust fault that soles to the decollement. Either of these models are perceivable with a duplex growing by underplating of the Indian plate into the Himalayan orogenic wedge contributing to higher rock uplift rates north of the Physiographic Transition-2. To the west of 77ºE, however, the landscape morphology indicates the Main Boundary Thrust makes a northward bend coinciding with the along-strike termination of the Physiographic Transition-2 and an arc-perpendicular Bouguer gravity anomaly reflecting a trough on the Indian plate near longitude 77°E. These data suggest that the Main Boundary Thrust merges along strike with the ramp or with an emergent fault soling into the Main Himalayan Thrust at this location, potentially marking a significant change in tectonic configuration along the Himalayan arc. / Graduate