Spelling suggestions: "subject:"brain - amagnetic resonance imaging"" "subject:"brain - asmagnetic resonance imaging""
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The characterization of white matter injury patterns in normal pressure hydrocephalus using magnetic resonance imagingKeong, Nicole Chwee Har January 2014 (has links)
No description available.
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Functional MRI research on language processing in Chinese children andadultsKwok, Sze-wei., 郭思蔚. January 2004 (has links)
published_or_final_version / abstract / toc / Linguistics / Master / Master of Philosophy
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Brain processing of semantics: fMRI evidence from monolinguals and bilingualsChan, Hiu-dan., 陳曉丹. January 2005 (has links)
published_or_final_version / abstract / Linguistics / Doctoral / Doctor of Philosophy
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Functional magnetic resonance imaging (FMRI) of brain and cervical spinal cord吳文卓, Ng, Man-cheuk. January 2007 (has links)
published_or_final_version / abstract / Orthopaedics and Traumatology / Doctoral / Doctor of Philosophy
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Plasticity of human brain networks as revealed by functional magnetic resonance imagingYuen, Sung-lai., 袁崇禮. January 2007 (has links)
The best for PhD thesis in the Faculties of Arts, Architecture, Business & Economics, Education, Law and Social Sciences (Universityof Hong Kong), Li Ka Shing prize, 2006-2007 / published_or_final_version / abstract / Psychology / Doctoral / Doctor of Philosophy
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Structural white matter abnormalities in never-medicated patients withfirst-episode schizophrenia: a diffusiontensor imaging studyCheung, Vinci, 張穎思 January 2008 (has links)
published_or_final_version / Psychiatry / Doctoral / Doctor of Philosophy
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From neuroimaging to proteomics in schizophreniaDeng, Yi, 鄧藝 January 2009 (has links)
published_or_final_version / Psychiatry / Doctoral / Doctor of Philosophy
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In vivo MRI study of the visual system in normal, developing and injured brainsChan, Chuen-wing, 陳泉榮 January 2010 (has links)
The Best PhD Thesis in the Faculties of Dentistry, Engineering, Medicine and Science (University of Hong Kong), Li Ka Shing Prize,2009-2010 / published_or_final_version / Electrical and Electronic Engineering / Doctoral / Doctor of Philosophy
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Brain processing of temporal information in language: an fMRI studyHuang, Song, Anna, 黄颂 January 2010 (has links)
published_or_final_version / Linguistics / Master / Master of Philosophy
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Magnetic resonance imaging investigation of normal and altered brain functions and metabolismsZhou, Yuwen, 周彧雯 January 2012 (has links)
Benefiting from higher SNR as well as better spatial, temporal and spectral resolution, magnetic resonance imaging (MRI) at high field has proved to be a valuable neuroimaging modality which provides comprehensive evaluation of the central nervous system non-invasively. The objectives of this doctoral work were to develop MRI methodologies and to assess the functional, metabolic and structural alterations in rodent brains under normal and manipulated conditions.
Firstly, to improve the functional sensitivity and spatial precision, a novel functional MRI (fMRI) method using balanced steady state free precession with intravascular susceptibility contrast agent was proposed and its feasibility was evaluated in rat visual system. This new approach was sensitized to cerebral blood volume (CBV) changes. It provided comparable sensitivity to conventional CBVweighted fMRI using echo planar imaging but with no severe image distortion and signal dropout. Robust negative responses during visual stimulation were observed and activation patterns were in excellent agreement with known neuroanatomy. As a promising alternative to conventional CBV-weighted fMRI, it was particularly suited for fMRI investigation of animal models at high field.
Secondly, the relationship between anatomical connections and resting-state fMRI connectivity was explored using a well-controlled animal model of corpus callosotomy. Both complete and partial callosotomy resulted in significant loss of interhemispheric connectivity in the cortical areas whose primary interhemispheric connections via corpus callosum (CC) were severed. Partial restoration of interhemispheric connectivity and increased intrahemispheric connectivity were also observed. The experimental findings directly supported that anatomical connections via CC play a primary and indispensable role in resting-state connectivity, and that resting-state networks could be dynamically reorganized or acquired directly or indirectly through the remaining anatomical connections.
Thirdly, proton magnetic resonance spectroscopy (1H MRS) was employed to monitor the longitudinal metabolic alterations elicited by exogenous stimulation and endogenous modification, respectively. Significantly lower hippocampal N-acetylaspartate (NAA) was observed in fear conditioning animals, indicating reduced neuronal dysfunction and/or integrity, which contributed to the trauma-related symptoms. Meanwhile, pregnant animals exhibited prominently higher hippocampal NAA level, reflecting the increased density of neurons in this region, which might facilitate supporting behaviors that involving learning and memory. The 1H MRS detection of ongoing neurochemical changes induced by fear conditioning and pregnancy, especially in the hippocampus, can shed light on the mechanisms of learning and memory and the neurochemical underpinnings of behavioral improvement in pregnant animals.
Lastly, manganese-enhanced MRI (MEMRI) was employed to investigate the hypoxic-ischemic (HI) injury in the late phase and the neural response to conditioned fear. Significantly higher enhancement in T1-weighted images was found in the peri-lesional region 24 hours after manganese administration and it colocalized with the increase in glial cell density in histological staining, demonstrating the existence of reactive gliosis in the late phase after HI injury. In fear conditioned animals, higher manganese uptake was observed in amygdala, hippocampus, paraventricular nucleus of hypothalamus and cingulate cortex, which were all highly-involved in the process of fear. These findings suggested MEMRI approach were useful in investigation of post-injury cellular events and functional reorganization as well as for in vivo mapping of neuronal activity. / published_or_final_version / Electrical and Electronic Engineering / Doctoral / Doctor of Philosophy
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