Thesis (Ph.D.)--University of Florida, 2004. / Typescript. Title from title page of source document. Document formatted into pages; contains 119 pages. Includes Vita. Includes bibliographical references.

Made available in DSpace on 2014-06-11T19:29:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-08-18Bitstream added on 2014-06-13T19:39:23Z : No. of bitstreams: 1 castro_mp_me_botfm.pdf: 325846 bytes, checksum: 488dfaca4c5d75ee2ad1616d30bc5819 (MD5) / Fundação de Ensino e Pesquisa em Ciências da Saúde (FEPECS) / Avaliar a sobrevida de recém-nascidos (RN) prematuros de acordo com a idade gestacional e peso ao nascer, e identificar as complicações da prematuridade associadas à maior mortalidade. Estudo prospectivo do tipo coorte. Foram incluídos RN entre 25 e 31 semanas e 6 dias nascidos vivos sem anomalias congênitas, e admitidos na UTI neonatal do Hospital Regional da Asa Sul, Brasília, entre 1º de agosto de 2009 e 31 de outubro de 2010. Os óbitos em sala de parto, não foram incluídos. Os RN foram estratificados em três faixas de idade gestacional: 25 a 27 semanas e 6 dias; 28 a 29 semanas e 6 dias; 30 a 31 semanas e 6 dias e acompanhados até 28 dias de vida. Variáveis independentes: dados gestacionais, de nascimento e evolução neonatal. Desfechos: sobrevida aos 28 dias e alterações no ultrassom de crânio. Para análise dos resultados utilizou-se o teste do Qui-quadrado, análise de variância, teste de Kruskal-Wallis, razão de risco com intervalo de confiança e regressão logística múltipla, com significância em 5%. A coorte compreendeu 198 prematuros < 32 semanas, estratificados em três grupos: G1=59 (25 a 27semanas e 6 dias), G2=43 (28 a 29 semanas e 6 dias) e G3=96 (30-31 semanas e 6 dias). Corioamnionite e reanimação ao nascimento foram mais frequentes em G1 e G2. Parto vaginal e RN PIG foram mais frequentes em G1. A morbidade neonatal foi inversamente proporcional à idade gestacional, exceto a enterocolite necrosante e a leucomalácia periventricular, que não diferiram entre os grupos. O risco de óbito foi significativamente maior em G1 e G2 em relação ao G3 (RR:4,14; IC:2,23-7.68 e RR=2,84; IC:1,41-5.74), respectivamente. A sobrevida em G1 foi de 52,5%, em G2 foi 67,4% e em G3 88,5%. A partir de 27 semanas e do peso de 700g a sobrevida foi maior que 50%. A regressão logística mostrou... / To assess the survival rates of premature infants according to gestational age and birth weight, and to identify complications of prematurity associated with higher mortality. Prospective cohort study. Preterm infants with gestational age between 25 and 31 weeks and 6 days, born alive without congenital anomalies, and admitted in the NICU of Hospital Regional da Asa Sul, Brasília, between August 1st 2009 and October 31, 2010 were included. Neonates who died in the delivery room were excluded. Neonate were stratified into three gestational age groups: 25- 27 weeks and 6 days; 28- 29 weeks and 6 days; 30-31 weeks and 6 days, and followed until 28 days of life. Gestational data, delivery data and neonatal course were analyzed. Outcome: survival at 28 days and cranial ultrasound abnormalities. Data analysis was performed using the chi-square test, analysis of variance and the Kruskal-Wallis test, hazard ratio with confidence interval and multiple logistic regression. The level of significance was 5%. The cohort comprised 198 preterm infants less than 32 weeks, stratified into three groups: G1=59 (25-27weeks and 6 days), G2=43 (28- 29 weeks and 6 days) and G3=96 (30-31 weeks and 6 days). Chorioamnionitis and resuscitation in the delivery room were more frequent in G1 and G2. Vaginal delivery and newborns small for gestational age occurred significantly more in G1. Neonatal morbidity was inversely proportional to gestational age, except for necrotizing enterocolitis and leukomalacia that did not differ between the groups. The risk of death was significantly higher in groups 1 and 2 compared to 3 (RR: 4.14, CI: 2,23-7 .68 and RR = 2.84, CI:1,41 5-.74), respectively. The logistic regression analysis showed that pulmonary hemorrhage (OR: 3.33, 95% CI 1.41 to 7.90) and hyaline membrane disease... (Complete abstract click electronic access below)

Thesis (Ed.D.)--Boston University / PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you. / The performance of a group of twenty brain-injured boys (mean IQ 117.4; mean chronological age 120.6 months) was compared with that of a control group of non-brain-injured boys (mean IQ 118.2; mean chronological age 128.6 months) on a battery of tests designed to measure perceptual processes underlying conceptual thinking. The experimental group was selected from the out-patient files of the Seizure Unit at Ohildrens Medical Center in Boston. The control group was drawn from a large elementary school in the greater Boston area. All children in both groups were enrolled in regular classrooms and groups were matched on the variable• ot WISC Full Scale IQ, chronological age, sex and socio-economic level. The battery of tests consisting of the WISC, the Grahm-Kendall Memory for Design, the Wisconsin Card sorting Teat, the Porteua Mazes and the Gilmore Sentence Completion Test was administered to each child in his own home. [TRUNCATED] / 2031-01-01

Thesis (Ph. D.)--University of Missouri--Columbia, 2003. / Typescript. Vita. Includes bibliographical references (leaves 309-329).

Diss. (sammanfattning) Stockholm : Karol. inst., 2005. / Härtill 5 uppsatser.

Diss. (sammanfattning) Stockholm : Karol. inst., 2006. / Härtill 4 uppsatser.

Diss. (sammanfattning) Umeå : Umeå universitet, 2009. / Härtill 5 uppsatser.

Thesis (Ph. D.)--University of Florida, 2003. / Title from title page of source document. Includes vita. Includes bibliographical references.

by Ramanee Darshanee Mahaliyana. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1993. / Includes bibliographical references (leaves 122-139). / Chapter Chapter 1 --- Head Injury :an overview --- p.1 / Chapter Chapter 2 --- Diffuse Axonal Injury --- p.20 / Chapter Chapter 3 --- Objectives of this study --- p.53 / Chapter Chapter 4 --- Materials and Methods --- p.58 / Chapter Chapter 5 --- Results --- p.66 / Chapter Chapter 6 --- Discussion --- p.98 / Chapter Chapter 7 --- Conclusions --- p.119 / References --- p.122

Cerebral haemodynamic status defined as cerebral vasoreactivity to carbon dioxide and pressure autoregulatory response, have been shown to be affected after traumatic brain injury (TBI) and correlate with the neurological condition and clinical outcome. Therefore, it is important to have a reliable method to determine the cerebral haemodynamic status in brain-injured patients. Blood flow velocity (BFV) measurement by transcranial Doppler ultrasonography (TCD) has been shown to give accurate indication of changes in cerebral blood flow (CBF). Transient hyperaemic response (THR) test with TCD measurement to assess the BFV response of middle cerebral artery to a brief compression of the ipsilateral carotid artery, provides a simple method for repeated assessment of the cerebrovascular autoregulatory reserve in brain injured patients. However, the test has not been validated systematically against classical assessment tests using TCD and gold standard CBF measurement. / The aims of this thesis are (1) to validate the non-invasive TCD and its haemodynamic tests with a more involved gold standard CBF measurement using stable xenon-enhanced computerized tomography. (2) To correlate the cerebral haemodynamic abnormalities with the patterns of neurochemical disturbance detected by intracerebral microdialysis. (3) To investigate the possibility to reverse or minimized the cerebral haemodynamic abnormalities and metabolic derangement by treatment. (Abstract shortened by UMI.) / The goal of intensive care management for TBI is to provide them with a favourable physiological and metabolic environment for recovery of the injured-compromised cells. The development of clinical intracerebral microdialysis has enabled documentation of the metabolic derangement that provides more understanding of the mechanism of brain damage. Continuous measurement of both neurochemical and physiological parameters including CPP defined as mean arterial blood pressure (ABP) minus intracranial pressure, BFV and CBF, enables study of the relationship between metabolic events and physiologic changes. Clinical management of patients with TBI has emphasized on maintaining an optimal cerebral perfusion pressure (CPP). This critical CPP can then be defined by TCD, CBF as well as the metabolic measurements. / Ng Chi Ping. / "June 2005." / Adviser: Wai-sang Poon. / Source: Dissertation Abstracts International, Volume: 67-01, Section: B, page: 0122. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2005 / Includes bibliographical references (p. 147-154). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstracts in English and Chinese. / School code: 1307.