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Examining the Association of Fruit and Vegetable intake and Breast and Prostate Cancer ScreeningYu, Mark 11 December 2009 (has links)
Breast and prostate cancer incidence and mortality have been steadily decreasing. Reasons for these reductions may be related to increased rates of cancer screening and other factors such as improvements in diet, including consumption of fruits and vegetables. We wanted to determine if individuals who get screened for breast and prostate cancer are more or less likely to consume adequate servings of fruit and vegetables. A cross-sectional study using the BRFSS survey was conducted. Individuals included in this study (n=26,222), were asked about their breast or prostate cancer screening history. They were also asked about their servings per day of fruit and vegetables. Statistical analyses were conducted using the SAS 9.2 software program. Logistic regression analyses were conducted on the variables and potential confounders. Over 40% of individuals who did not screen for breast and prostate cancer were in the 50-59 years of age category. A trend was seen with younger age groups being less likely to consume 3 or more daily servings of fruit and vegetables than their older counterparts. Another trend was seen in education levels. Individuals with lower education were less likely to consume at least 3 daily servings of fruit and vegetables. There was a statistically significant association between cancer screening and servings of fruit and vegetables per day. Individuals who were screened for either breast or prostate cancer were 52% more likely to consume 3 or more servings of fruit and vegetables than those who did not screen for either breast or prostate cancer (OR=1.52, 95% CI: 1.29-1.79). Further research needs to be conducted related to how other health behaviors may be related to cancer screening adherence and fruit/vegetable intake.
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Avaliação dosimétrica de propostas de planejamento radioterápico para tratamento de mama e próstataOLIVEIRA, Fernanda Lucia de 09 October 2015 (has links)
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Previous issue date: 2015-10-09 / CAPES / Entre os tipos de câncer mais comuns no Brasil estão o de mama, com 57 mil novos casos, e o de próstata, com 69 mil novos casos, de acordo com estimativas 2014-2015 do Instituto Nacional de Câncer – INCA/Ministério da Saúde. Para o tratamento dessa enfermidade, a radioterapia é um método bastante eficaz, contudo expõe órgãos sadios que se encontram próximo ao volume alvo (pulmão e coração, no caso da mama, reto e bexiga no caso da próstata). Assim, o objetivo deste trabalho é avaliar um método de planejamento radioterápico, que reduza a dose nos órgãos risco, a partir da avaliação dosimétrica, baseada nas recomendações da Agência Internacional de Energia Atômica (AIEA) e da Comissão Internacional de Unidades e Medidas Radiológicas (ICRU). Utilizou-se a técnica de simulação do tratamento em um fantoma padrão Alderson-RANDO, com a inserção de dosímetros termoluminescentes LiF-100 para avaliação da dose. Os resultados mostraram que as doses nos órgãos risco para tratamento da mama foi abaixo de 4% da dose prescrita, e para o tratamento da próstata, na primeira etapa foi 55% abaixo da dose prescrita e na segunda menos de 5%. O resultado final demonstrou que os órgãos risco receberam doses baixas, no que se conclui que o método proposto reduzirá dos efeitos tardios ou toxidades que afetam a sobrevida dos pacientes. / Among the most common types of cancer in Brazil are the breast, with 57,000 new cases and prostate, with 69,000 new cases, according to estimates from the 2014-2015 National Cancer Institute - INCA / Ministry of Health. For the treatment of this disease, radiation therapy is a very effective method, however exposes healthy organs that are close to the target volume (lung and heart, in the case of the breast, rectum and bladder in the case of the prostate). The objective of this study is to evaluate a radiotherapy planning method, which reduces the dose in risk organs from the dosimetric evaluation, based on the recommendations of the International Atomic Energy Agency (IAEA) and the International Commission Units and Radiological measures (ICRU). We used a simulation technique of treatment on a standard Alderson-Rando phantom, with the insertion of thermoluminescent dosimeter LiF -100 for evaluation dose. The results showed that doses organs at risk for breast cancer treatment was below 4% of the prescribed dose, and prostate treatment, in the first stage was 55% lower than the prescribed dose and the second less than 5%. The result showed that the risk organs received low doses, as it is concluded that the proposed method will reduce the late effects or toxicities that affect patient survival.
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Inhibition of Epithelial-to-Mesenchymal Transition by Anti-tumor Agents in Cancer CellsChou, Chih-Chien 21 August 2014 (has links)
No description available.
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A Content Analysis of the Counseling Sessions of Dyads with Breast and Prostate Cancer: Linguistic Predictors of Psychosocial Adjustment and Thematic Analysis of Key ConcernsDorros, Sybilla M. January 2010 (has links)
The purpose of this investigation was to explore how participants' language use during counseling (overall emotional expression, positive emotional expression, and communal coping, or "we-talk") was associated with superior adjustment, as measured by four psychosocial outcome variables (depression, positive affect, negative affect, and relationship satisfaction); as well as to identify the key concerns of dyads with cancer, how concerns differed by role and sex, and if they were associated with participants' well-being. The present study was a content analysis of the counseling sessions of 43 dyads (N = 86) with breast and prostate cancer. Using a multi-method approach, the audio recordings of 228 counseling sessions were transcribed and analyzed linguistically (quantitatively) and thematically (qualitatively).Results of the linguistic analyses revealed that participant's use of "we-talk" had the most consistent and beneficial effect on outcomes; specifically improved depression, negative affect, and relationship satisfaction. These findings suggest that it might not be as important how much a person expresses themselves emotionally, but rather, whether they have a close relational partner that they see as an instrumental part of their coping process and significantly intertwined in their life, which is reflected in their language use of communal coping.Results of the thematic analyses revealed that survivors' concerns were more focused on cancer and treatment related issues, whereas partners' concerns centered on the well-being of their spouse/partner with cancer, and what they were doing to help their loved one cope with his/her illness. The overarching key concern that was intertwined in participants' discourse was frequent discussion of relationship maintenance, negotiation, and communication issues. In addition, discussion of these concerns showed greatest benefits for women with breast cancer.The findings of this study has implications for counselors and clinicians in that language use and topics discussed during counseling have the potential to increase psychosocial adjustment for dyads coping with cancer. The general discourse of survivors mirrored that of their partners, which indicates that helping to modify or change how one person speaks, has the potential to influence how their partner talks as well; which has implications for the well-being of both dyad members.
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