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Efficacy of four irrigation protocols in the debridement of small apical accessory canalsWitek, Thomas J. January 1997 (has links)
Thesis (M.S.)--Marquette University, 1997.
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Standardized endodontic technique morphometric and clinical studies /Kerekes, Kasmer. January 1980 (has links)
Thesis (doctoral)--University of Oslo, 1980. / Includes reprints of 7 papers by author.
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An experimental and computational investigation of dielectrics for use in quarter wave coaxial cavity resonatorsLowery, Andrew D. January 2006 (has links)
Thesis (M.S.)--West Virginia University, 2006. / Title from document title page. Document formatted into pages; contains xii, 153 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 133-135).
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Longitudinal assessment of age-related change in the dental pulp chamber and age estimation using dental radiographsMcBride, David Glynn. January 2007 (has links)
Thesis (Ph. D.)--University of Missouri-Columbia, 2007. / The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on September 28, 2007) Vita. Includes bibliographical references.
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Molecular Control of the δ-opioid Receptor Signaling and Functional Selectivity by SodiumBlgacim, Nuria 27 June 2018 (has links)
Accumulating evidence suggests a prominent role of the arrestin-dependent signaling pathway in triggering most of the deleterious side effects observed using δ-OR targeting drugs. Numerous small molecules targeting the δ-OR receptors have been developed but their pharmacological properties, including their functional selectivity, have been poorly characterized. The absence of functionally selective opioid drugs, and the lack of knowledge of the pharmacological profile and signaling properties of the δ-OR receptor, limits its therapeutic exploitation. The development of functionally selective modulator toward the canonical G protein pathway could importantly increase the therapeutic potential of this receptor while decreasing its deleterious effects. An approach to fine-tune the functional selectivity of a GPCR is by using allosteric modulators. These allosteric modulators would reduce problems associated with drugs targeting the orthosteric site by not chronically activating the receptor. The overall goal of the proposed research is to study the molecular mechanism by which sodium-channel inhibitors allosterically regulates the delta opioid receptor (δ-OR) signaling and functional selectivity. Additionally, the signaling features of the δ-OR signal transduction triggered by biased receptor activation have been investigated. A combination of approaches, including functional studies, molecular modeling and mutagenesis, were used to study the general mechanism underlying the activation and tuning of the δ-OR signal transduction behavior. Thus, this work suggests the druggability of the allosteric sodium pocket by using sodium channel inhibitors. The current research represent discovery of two different allosteric profiles for the β-arrestin recruitment and one allosteric profile for the G-protein pathway at activated DOR and would serve as scaffold for further refinement of modulators with the desired pharmacological profile.
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Uso do laser de COsub(2) ou bisturi a frio para a remoção de pigmento melânico gengival - estudo clínico comparativo em pós-operatório precoceKOEGLER, VERA L. 09 October 2014 (has links)
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Estudo dos efeitos do laser em baixa intensidade na reparação em mucosa bucal de ratosTASSINARI, SILVIA C. 09 October 2014 (has links)
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Efeito do laser de diodo (808 nm) de alta potência no crescimento de cultura de células de fibroblastos humanosPOLIDO, CRISTIANE B. 09 October 2014 (has links)
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Estudo da redução microbiana intracanal utilizando laser de baixa potência associado a fotossensibilizador e laser de alta potênciaKAIRALLA, ELENI C. 09 October 2014 (has links)
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Avaliação in vitro da resistência à tração de um sistema de retenção intracanal em condutos radiculares irradiados com laser de Er:YAG e de Nd:YAGMELLO, NADIA J.C. 09 October 2014 (has links)
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