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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

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Frequency of CCR2V64I and CCR5Δ32 host genes and their association with HIV infection among pregnant women from Harare, Zimbabwe

Soko, White January 2010 (has links)
Magister Public Health - MPH / Aim: To determine and compare the prevalence of CCR5-Δ32 and CCRV64I genes in HIV positive and HIV negative population of pregnant women from Harare, in Zimbabwe. Results: The proportion of pregnant women with the homozygous CCR2V64I gene was 24.38% and this gene was two times more associated with HIV infection than in those without it ( RR= 2.32, 95% CI-1.38-3.92). No CCR5-Δ32 deletion was detected in the studied population. Conclusion: The homozygous CCR2V64I gene and STIs were more prevalent in HIV infected pregnant women than in uninfected pregnant women and no homozygousCCR5-Δ32 gene was detected in this study. / South Africa
HIV in pregnant women
Host genetic factors
Gene polymorphism
Mutation
Protective effect
CCR5-Δ32
CCR2V64
Vaccines
Chemotherapeutic drugs
Zimbabwe

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