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Focal Wrist Cooling Does Not Alter Indices of Spinal Excitability in the Flexor Carpi Radialis MuscleCameron, Shawn P. 26 July 2011 (has links)
No description available.
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Increases in corticospinal responsiveness during a sustained submaximal plantar flexionHoffman, Benjamin Unknown Date (has links)
Studying the responsiveness of specific central nervous system (CNS) pathways to electrical or magnetic stimulation can provide important information regarding fatigue processes occurring as a result of ongoing muscle activity. While there are some studies assessing CNS responsiveness during sustained maximal voluntary contractions (MVCs) few papers have examined such changes during sustained submaximal contractions, particularly in muscles of the lower limbs. The location of the underlying central fatigue process can be partially determined by assessing the responsiveness to magnetic or electrical stimulation at different sites along the CNS. This has been investigated during maximal and submaximal contractions in the upper limb muscles, however changes in corticospinal responsiveness at different CNS locations has yet to be determined during fatigue of lower limb muscles. Therefore, the focus of this study was to investigate changes in corticospinal responsiveness during a sustained submaximal contraction of the triceps surae. Comparisons were made between the size of motor evoked potentials (MEPs) elicited by motor cortical stimulation and cervicomedullary motor evoked potentials (CMEPs) elicited via magnetic stimulation of the descending tracts, in order to determine the site of any change in corticospinal responsiveness. Participants maintained an isometric contraction of triceps surae at 30% of MVC for as long as possible on two occasions. Stimulation was applied either to the motor cortex or to the cervicomedullary junction every minute during a contraction until task failure. Peripheral nerve stimulation was also applied to evoke maximal M-waves (Mmax) and a superimposed twitch. Additionally, MEPs and CMEPs were evoked during brief contractions at 80, 90 and 100% MVC as a non-fatigue control. During the sustained contractions, MEP size increased significantly in both soleus (113%; SOL) and medial gastrocnemius (108%; MG) and at endurance limit matched MEP size in the pre-fatigue MVC (≈20-25% Mmax). In contrast, CMEP size increased significantly in MG (51%) but not in SOL (63%), and at endurance limit was significantly smaller than during pre-fatigue MVC (5-6% Mmax versus 11-13% Mmax). The data indicate that cortical processes contribute substantially to the increase in corticospinal responsiveness observed during sustained submaximal contraction of triceps surae. The strength of corticospinal projections and the upper-limit of motor unit recruitment may explain differences in corticospinal responsiveness between SOL and upper arm muscles. Furthermore, differences in motor unit recruitment and firing rate may explain differences in spinal responsiveness between submaximal and maximal voluntary contractions.
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Neural Mechanisms of Task Failure During Sustained Submaximal ContractionsWilliams, Petra S. 26 September 2013 (has links)
No description available.
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