Thèse d'exercice : Pharmacie : Université de Nantes : 2004. / Bibliogr. f. 152-156 [57 réf.].

Thèse de doctorat : Sciences du langage : Lyon 2 : 2001. / Titre provenant de l'écran-titre. Bibliogr.

Thèse d'exercice : Pharmacie : Université de Nantes : 2004. / Bibliogr. f. 160-171 [104 réf.].

Thèse doctorat : Génie des matériaux : Ecully, Ecole centrale de Lyon : 2008. / 80 références.

Thèse doctorat : Génie des matériaux : Ecully, Ecole centrale de Lyon : 2008. / Titre provenant de l'écran-titre. 80 références.

Thesis (doctoral)--Grossherzoglich Hessische Ludwigs-Universität zu Giessen, 1913. / "Sonderabdruck aus: Prace matematyczno-fizyczne XXVI"--T.p. verso. Pages also numbered 136-202. Vita. Includes bibliographical references.

Thesis--Ph. D., University of Hong Kong, 1987.

No description available.

In this thesis, we discuss a novel approach to the dynamics modelling and analysis of impact in unilaterally constrained multibody systems. This approach is based on an analysis of energy absorption and restitution during impact, using a decomposition technique, which decouples the kinetic energy associated with the spaces of admissible and constrained motions of unilateral contacts. This is done based on the decomposition of the tangent space of the configuration manifold at the pre-impact instant. The decomposition of the kinetic energy can provide a picture of how the energy absorption and dissipation during impact is related to the variation of the generalized velocities and the configuration of multibody systems. / Further, based on the above analysis approach, we introduce a new interpretation of the energetic coefficient of restitution, specially applicable to contact involving multibody systems. This interpretation generalizes the concept of the energetic coefficient of restitution and allows for consideration of simultaneous multiple-point contact scenarios. Moreover, based on the concept of the generalized energetic coefficient of restitution, the contact modes and the post-impact state of planar single-point impact are determined. Further, the problem of simultaneous multiple-point impact is considered, where it is shown that our approach can also be advantageous to characterize the dynamics of interaction in such systems. / The use and applicability of the approach reported are further investigated by conducting an experimental study on a robotic testbed. The open architecture of the testbed allows us to perform various contact experiments, such as single- and multiple-point impact scenarios, with different pre-impact configurations and velocities. The kinematic and dynamic models of the system have been developed and implemented for real-time analysis. It is shown that impact between multibody systems is considerably affected by not only the local dynamics characteristics of the interacting bodies, but also the (global) configuration of the interacting multibody systems. The reported results suggest that the material presented herein offers a useful means to characterize impact in complex systems.

One approach to protein structure prediction is to first predict from sequence, a thresholded and binary 2D representation of a protein's topology known as a contact map. Then, the predicted contact map can be used as distance constraints to construct a 3D structure. We focus on the latter half of the process and aim to obtain a set of non-binary distance constraints from contacts maps. This thesis proposes an approach to extend the traditional binary definition of “in contact” by incorporating fuzzy logic to construct fuzzy contact maps from a set of contact maps at different thresholds, providing a vehicle for error handling. Then, a novel template-based similarity search and distance geometry methods were applied to predict distance constraints in the form of a distance map. The three-dimensional coordinates were then calculated from the predicted distance constraints. Experiments were conducted to test our approach for various levels of noise. As well, we compare the performance of fuzzy contact maps to binary contact maps in the framework of our methodology. Our results showed that fuzzy contact map similarity was indicative of distance map similarity. Thus, we were able to retrieved similar distance map regions using fuzzy contact map similarity. The retrieved distance map regions provided a good starting point for adaptation and allowed for the extrapolation of missing distance values. We were thus able to predict distance maps from which, the three-dimensional coordinates were able to be calculated. Testing of this framework on binary contact maps revealed that fuzzy contact maps had better performance with or without noise due to a stronger correlation between fuzzy contact map similarity and distance map similarity. Thus, the methodology described in this thesis is able to predict good distance maps from fuzzy contact maps in the presence of noise and the resulting coordinates were highly correlated to the performance of the predicted distance maps. / Thesis (Ph.D, Computing) -- Queen's University, 2012-05-23 13:59:28.12