Ph.D.

Thesis (M.S.)--Florida State University, 2004. / Advisor: Dr. Joseph J. Pignatiello, Jr., Florida State University, College of Engineering, Department of Industrial Engineering. Title and description from dissertation home page (viewed June 17, 2004). Includes bibliographical references.

Thesis (M.S.)--Florida State University, 2004. / Advisor: Dr. Joseph J. Pignatiello, Jr., Florida State University, College of Engineering, Department of Industrial Engineering. Title and description from dissertation home page (viewed June 17, 2004). Includes bibliographical references (p 53-55).

Thesis (M.S.)--West Virginia University, 2006. / Title from document title page. Document formatted into pages; contains ix, 94 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 91-94).

For the last several decades, sequential change point problems have been studied in both the theoretical area (sequential analysis) and the application area (industrial SPC). In the conventional application, the baseline process is assumed to be stationary, and the shift pattern is a step function that is sustained after the shift. However, in biosurveillance, the underlying assumptions of problems are more complicated. This thesis investigates several issues in biosurveillance such as non-homogeneous populations, spatiotemporal surveillance methods, and correlated structures in regional data. The first part of the thesis discusses popular surveillance methods in sequential change point problems and off-line problems based on count data. For sequential change point problems, the CUSUM and the EWMA have been used in healthcare and public health surveillance to detect increases in the rates of diseases or symptoms. On the other hand, for off-line problems, scan statistics are widely used. In this chapter, we link the method for off-line problems to those for sequential change point problems. We investigate three methods--the CUSUM, the EWMA, and scan statistics--and compare them by conditional expected delay (CED). The second part of the thesis pertains to the on-line monitoring problem of detecting a change in the mean of Poisson count data with a non-homogeneous population size. The most common detection schemes are based on generalized likelihood ratio statistics, known as an optimal method under Lodern's criteria. We propose alternative detection schemes based on the weighted likelihood ratios and the adaptive threshold method, which perform better than generalized likelihood ratio statistics in an increasing population. The properties of these three detection schemes are investigated by both a theoretical approach and numerical simulation. The third part of the thesis investigates spatiotemporal surveillance based on likelihood ratios. This chapter proposes a general framework for spatiotemporal surveillance based on likelihood ratio statistics over time windows. We show that the CUSUM and other popular likelihood ratio statistics are the special cases under such a general framework. We compare the efficiency of these surveillance methods in spatiotemporal cases for detecting clusters of incidence using both Monte Carlo simulations and a real example. The fourth part proposes multivariate surveillance methods based on likelihood ratio tests in the presence of spatial correlations. By taking advantage of spatial correlations, the proposed methods can perform better than existing surveillance methods by providing the faster and more accurate detection. We illustrate the application of these methods with a breast cancer case in New Hampshire when observations are spatially correlated.

Thesis (Ph. D.)--University of Missouri-Columbia, 1996. / Typescript. Vita. Includes bibliographical references (leaves 438-450). Also available on the Internet.

Thesis (Ph. D.)--University of Missouri-Columbia, 1996. / Typescript. Vita. Includes bibliographical references (leaves 438-450). Also available on the Internet.

D.Phil. / We propose solutions to two statistical problems using the frequency domain approach to time series analysis. In both problems the data at hand can be described by the well known signal plus noise model. The first problem addressed is the estimation of the underlying variance of a process for the use in a Shewhart or CUSUM control chart when the mean of the process may be changing. We propose an estimator for the underlying variance based on the periodogram of the observed data. Such estimators have properties which make them superior to some estimators currently used in Statistical Quality Control. We also present a CUSUM chart for monitoring the variance which is based upon the periodogram-based estimator for the variance. The second problem, stimulated by a specific problem in Variable Star Astronomy, is to test whether or not the mean of a bivariate time series is constant over the span of observations. We consider two periodogram-based tests for constancy of the mean, derive their asymptotic distributions under the null hypothesis and under local alternatives and show how consistent estimators for the unknown parameters in the proposed model can be found