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I, Synthesis and polymerization of nortricyclene derivatives ; II, 1:1 alternating copolymers of bicyclobutanesRhoades, James Wesley, 1947- January 1971 (has links)
No description available.
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CHARACTERIZATION OF PEPTIDE CYCLASE 1 (PCY1), A SERINE PROTEASE-LIKE ENZYME INVOLVED IN CYCLIC PEPTIDE BIOSYNTHESIS IN PLANTS2013 November 1900 (has links)
Plants within the Caryophyllaceae, and certain other families, produce cyclic peptides (CPs) which generally consist of 5–12 proteinogenic amino acids. Until recently, very little was known about the biosynthesis of CPs in the Caryophyllaceae. Recently, in the Covello lab, two enzymes in Saponaria vaccaria were found to be involved in the processing of ribosome-derived linear precursors, giving rise to cyclic peptides. Thus, oligopeptidase 1 (OLP1) and peptide cyclase 1 (PCY1) are involved in the biosynthesis of segetalin A (a six-membered CP) from a 32 amino acid linear peptide precursor called presegetalin A1. PCY1 carries out the unusual cyclization reaction to form mature segetalin A from a linear intermediate. The purified recombinant PCY1, the first cloned plant enzyme whose function is peptide cyclization, was identified as a homologue of a prolyl-oligopeptidase from the S9 serine protease family. In principle, PCY1 performs an intra-molecular transpeptidation reaction to produce a CP. A homology-based structural model of PCY1 suggests that it has two domains, a catalytic α/β hydrolase domain and an unusual β- propeller domain. In an effort to define the substrate specificity of PCY1, a wide variety of synthetic peptide precursors were tested in assays and the results are discussed.
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Approaches to (-)-#alpha#-kainic acid and analogues by intramolecular anionic cyclizationRathmell, Richard E. January 1998 (has links)
No description available.
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Nucleophilic cleavage of organic disulphidesSalim, A. M. January 1988 (has links)
No description available.
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Selected reactions of some cyclic sulfoxides /Kreh, Donald Willard, January 1966 (has links)
Thesis (Ph. D.)--Virginia Polytechnic Institute, 1966. / Vita. Abstract. Includes bibliographical references (leaves 121-125). Also available via the Internet.
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Bioactive compounds from the marine sponge Geodia barretti : characterization, antifouling activity and molecular targets /Sjögren, Martin, January 2006 (has links)
Diss. (sammanfattning) Uppsala : Uppsala universitet, 2006. / Härtill 5 uppsatser.
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Synthesis and biological evaluation of novel MPTP analogs as potential monoamine oxidase B inhibitors /Kalgutkar, Amit S., January 1993 (has links)
Thesis (Ph. D.)--Virginia Polytechnic Institute and State University, 1993. / Vita. Abstract. Includes bibliographical references (leaves 276-302). Also available via the Internet.
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Regulation of bone resorption by the adenylate cyclase-cyclic AMP system a biochemical study on mouse calvarial bones and isolated bone cells /Ransjö, Maria. January 1988 (has links)
Thesis (doctoral)--Umeå Universitet, Sweden, 1988. / Extra t.p. with thesis statement inserted. Includes bibliographical references.
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New methods for the synthesis of fused ring structuresGutsche, C. David January 1947 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1947. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 167-171).
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Cellular mechanisms involved in bone resorptionLerner, Ulf. January 1980 (has links)
Thesis (doctoral)--University of Umeå, 1980. / Cover title. Abstract of the thesis inserted. Includes bibliographical references (leaves [37]-64).
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