Global ETD Search

1	Characterisation and analysis of the prostate-specific membrane antigen promoter McDonald, Bernadette Catherine January 2000 (has links) No description available. 610 Cancer; Gene therapy
2	Development of novel polymeric nanoparticles for cancer gene therapy Yao, Hong, 姚宏 January 2011 (has links) published_or_final_version / Chemistry / Doctoral / Doctor of Philosophy Nanoparticles. Cancer - Gene therapy.
3	Engineering novel suicide enzymes for improved cancer gene therapy Ardiani, Andressa. January 2009 (has links) (PDF) Thesis (Ph. D.)--Washington State University, May 2009. / Title from PDF title page (viewed on June 15, 2009). "School of Molecular Biosciences." Includes bibliographical references. Cancer Cancer Gene therapy
4	On the classification of cancer cell gene via expressive value distance (EVD) algorithm and its comparison to the optimally trained ANN method Zhang, Tong January 2011 (has links) University of Macau / Faculty of Science and Technology / Department of Mathematics Cancer cells Cancer -- Gene therapy
5	Development of a novel hTERTC27 based cancer: gene therapy Gao, Yi, 高毅 January 2007 (has links) published_or_final_version / abstract / Microbiology / Doctoral / Doctor of Philosophy Glioblastoma multiforme. Cancer - Gene therapy. Polypeptides.
6	Progress toward a combined bacterial and viral gene delivery system for mammalian cells Simper, Melissa Sue 28 August 2008 (has links) Not available / text Breast--Cancer--Gene therapy Genetic vectors
7	Targeted gene delivery using a receptor-mediated gene transfer system and chemosensitivity in hepatocellular carcinoma Lee, Kin-wah, Terence, 李建華 January 2000 (has links) The Best MPhil Thesis in the Faculties of Dentistry, Engineering, Medicine and Science (University of Hong Kong), Li Ka Shing Prize / published_or_final_version / Pathology / Master / Master of Philosophy Liver - Cancer - Gene therapy. Genetic transformation.
8	Growth inhibition of human multiple myeloma cells by a conditional-replicative, oncolytic adenovirus armed with the CD154 (CD40-ligand) transgene Rodrigues, Margret S. Tong, Alex W. January 2006 (has links) Thesis (Ph.D.)--Baylor University, 2006. / Includes bibliographical references (p. 100-115).
9	Role of Nanotechnology and Gene Delivery Systems in TRAIL-Based Therapies Naoum, George E., Tawadros, Fady, Farooqi, Ammad Ahmad, Qureshi, Muhammad Zahid, Tabassum, Sobia, Buchsbaum, Donald J., Arafat, Waleed 01 August 2016 (has links) Since its identification as a member of the tumour necrosis factor (TNF) family, TRAIL (TNF-related apoptosis-inducing ligand) has emerged as a new avenue in apoptosis-inducing cancer therapies. Its ability to circumvent the chemoresistance of conventional therapeutics and to interact with cancer stem cells (CSCs) self-renewal pathways, amplified its potential as a cancer apoptotic agent. Many recombinant preparations of this death ligand and monoclonal antibodies targeting its death receptors have been tested in monotherapy and combinational clinical trials. Gene therapy is a new approach for cancer treatment which implies viral or non-viral functional transgene induction of apoptosis in cancer cells or repair of the underlying genetic abnormality on a molecular level. The role of this approach in overcoming the traditional barriers of radiation and chemotherapeutics systemic toxicity, risk of recurrence, and metastasis made it a promising platform for cancer treatment. The recent first Food Drug Administration (FDA) approved oncolytic herpes virus for melanoma treatment brings forth the potency of the cancer gene therapy approach in the future. Many gene delivery systems have been studied for intratumoural TRAIL gene delivery alone or in combination with chemotherapeutic agents to produce synergistic cancer cytotoxicity. However, there still remain many obstacles to be conquered for this different gene delivery systems. Nanomedicine on the other hand offers a new frontier for clinical trials and biomedical research. The FDA approved nanodrugs motivates horizon exploration for other nanoscale designed particles' implications in gene delivery. In this review we aim to highlight the molecular role of TRAIL in apoptosis and interaction with cancer stem cells (CSCs) self-renewal pathways. Finally, we also aim to discuss the different roles of gene delivery systems, mesenchymal cells, and nanotechnology designs in TRAIL gene delivery. apoptosis cancer gene therapy nanotechnology TRAIL
10	Identification and characterization of cancer-related genes in esophageal squamous cell carcinoma Fu, Li, 付利 January 2007 (has links) published_or_final_version / abstract / Clinical Oncology / Doctoral / Doctor of Philosophy Esophagus - Cancer. Cancer - Gene therapy. Cancer - Genetic aspects.

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