Downy mildew of broccoli, cabbage, and cauliflower is caused by the plant pathogenic fungus Peronospora parasitica. Cool damp weather with high humidity is highly favorable for sporulation, dissemination of spores, and infection by this pathogen. The severity of disease is affected by the duration of these weather conditions favorable for disease development. Potential new fungicides were evaluated for disease control in a field trial conducted in the winter of 1992-93. For broccoli, no significant differences in disease severity were detected among treatments. On the other hand, Microthiol and Microthiol + Maneb significantly reduced the number of downy mildew lesions on cabbage and cauliflower compared to nontreated plants. Maneb alone provided significant disease control on cabbage, but not on cauliflower.