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Ophthalmic BiomaterialsMuirhead, Ben 11 1900 (has links)
This thesis will explore, both generally and very specifically, the role of biomaterials in drug delivery and tissue engineering applications. A novel therapeutic conjugate to treat dry eye disease using hyaluronic acid and sulfadiazine was created and tested using a benzalkonium chloride induced dry eye model. Thermoresponsive hydrogels based around poly(n-isopropylacrylamide) were synthesized to create a potential in situ gelling cell scaffold for cell delivery to the subretinal space. Finally, a mucoadhesive micelle was developed as a platform delivery system to increase bioavailability of drug in anterior segment therapeutics. / Thesis / Doctor of Philosophy (PhD)
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FIBER-COMPOSITE IN SITU FABRICATION: MULTILAYER COEXTRUSION AS AN ENABLING TECHNOLOGYJordan, Alex Michael 13 September 2016 (has links)
No description available.
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