Thesis--Catholic University of America. / Bibliography: p. 26-27.

Thesis (Ph. D.)--University of Wisconsin--Madison, 1959. / Typescript. Abstracted in Dissertation abstracts, v. 19 (1959) no. 12, p. 3261. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 228-233).

Thesis (Ph. D.)--University of Wisconsin--Madison, 1976. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leave 101-102).

Thesis (Ph. D.)--University of Texas at Austin, 2005. / Vita. Includes bibliographical references.

Thesis (M. S.)--Civil and Environmental Engineering, Georgia Institute of Technology, 2007. / Huang, Ching-Hua, Committee Chair.

Summary: Partially chlorosulphated derivatives were synthesised for the purpose of examining the reactions of the chlorosulphonyloxy group in the presence of free hydroxyl groups. The behaviour of the chlorosulphonyloxy group was investigated under acidic conditions. Since sterically favoured chlorosulphonyloxy groups undergo facile replacement by chlorine to form chlorodeoxy sugars, some compounds possessing chlorosulphonyloxy groups which,due to polar and steric effects are not replaced by chloride,were investigated with a view to possible activation of the unfavourable centres towards nucleophilic substitution, thereby making available previously inaccessible chlorodeoxy sugars.

The decomposition of acylarylnitrosamines in benzene and halogenomethanes has been studied. "Benzyne adducts" are formed in yields up to 82% in the decomposition of N-nitrosoacetanilide in the presence of various 2,3,4,5-tetraarylcyclopenta- dienones and anthracenes, and competition reactions using mixtures of arynophiles gave competition constants identical to those from similar reactions using authentic sources of benzyne, W-Nitroso- acetanilide did not, however react with furan to form l,4-dlhydronaphthalene-l,4-endoxide, and the yield of 1,2,3,4-tetraphenylnaphthalene formed in the reaction with 2,3,4,5-tetraphenylcyclopenta- dienone in benzene was gradually reduced from 22% to 1.4% on addition of furan, N-Nitrosoacetanilide has been shown to react with dimethylacetylene- dicarboxylate in benzene to give cis-, and trans- dimethyl diphenylmaleates and 1,2,3,4-tetracarbo- methoxynaphthalene in good yield, in addition to the expected biphenyl. The reaction of benzyne from pentyl nitrite and anthranllic acid, however, gave only 5,6,11,12-tetracarbomethoxydlbenzo [a,ej cyclooctatetraene. These results are discussed, and the suggestion made that the intermediate leading to the formation of "aryne adducts" need not be a true aryne. An arynoid species, the dipolar conjugate base of the aryldlazonium cation, formed by removal of the o-proton, is suggested as a possible alternative. The reactions of acylarylnitrosamines with halogenomethanes have also been studied, and the results compared with those of similar reactions of arylazotriphenylmethanes and aryldlazonium halides and fluoroborates. The participation of diazoniam halides and acetate has been demonstrated in the reactions of N-nitrosoacetanilide, and possible mechanisms involving formation of diazonium halides have been suggested. The decomposition of o-t-butyl-N-nitroso-acetanilide in halogenomethanes led to the formation of the o-, and m-t-butylphenyl halides, in addition to the o-, and m-t-butylphenyl acetates. Participation of 3-t-butylbenzyne was confirmed by the isolation of 5-t-butyl-l,4-dihydronaphthalene-1,4-endoxide when o-t-butyl-N-nitrosoacetanilide was allowed to decompose in bromotrichloromethane in the presence of furan; this was accompanied by a suppression of formation of the m-t-butylphenyl halides and acetate, A reaction scheme is suggested involving participation of diazonium halides and acetate. The reaction of N-nitroso-N-formylanthranilic acid and N-nitroso-N-acetylanthranilic acid with 2,3,4,5-tetraphenylcyclopentadlenone in benzene led to the formation of 1,2,3,4-tetraphenylnaph- thalene, but the principal products in these reactions were 3,1-benzoxazin-4-one and 2-methyl-3,1-benzoxazin-4-one respectively.

An investigation of the reaction of the sulphuryl chloride-N, N-dimethyl formamide reagent with several carbohydrate compounds, containing free hydroxyl groups, was undertaken, mainly with the view of looking at substitution of the hydroxyl groups with chlorine atoms. The reaction was found to lead to substitution of both primary and secondary hydroxyl groups with chlorine, with inversion of configuration in the latter case. The reagent was further found to effect formylation and chlorosulphation of secondary hydroxyl groups, where nucleophilic substitution by a chlorine was not favourable. Studies involving the methyl pentopyranosides, showed that the reagent was particularly useful in the chlorosulphation and chlorination of sugars, compared with the hexopyranosides.

No description available.

No description available.