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Yes / Richard Guthrie describes the central pillars of the verification regime for the Chemical Weapons Convention and assesses the relevance of a similar verification architecture for the Biological and Toxin Weapons Convention.

Yes / Acceleration of the applications of cutting edge science is often most likely in situations involving conflict and warfare between different groups. That is the focus of this paper. It asks what we know of the past, present and possible future applications of advances in our understanding of the brain in the development of chemical weapons, and what might best be done to moderate the most dangerous aspects of that process at the present time, particularly by members of civil society. The paper therefore begins by examining this possibility of hostile manipulation of the brain in some detail. It then briefly reviews the current state of the chemical and biological arms control and disarmament regime as embodied in the Biological and Toxin Weapons Convention (BTWC) and the Chemical Weapons Convention (CWC) following the 2016 8th Five Year Review Conference of the BTWC and in the lead up to the 2018 4th Five Year Review Conference of the CWC. Finally, our civil society initiative to assist in achieving a successful outcome of the 2018 CWC Review Conference is described. This initiative involves the production of a multi-authored edited book, to be published in advance of the Review Conference by the UK Royal Society of Chemistry that explores many of the critical issues facing the CWC States Parties as they seek to agree effective measures to prevent the development and use of chemical weapons, as the life and chemical sciences advance.

Yes / Stark illustrations of the dangers from chemical weapons can be seen in attacks using toxic industrial chemicals and sarin against civilians and combatants in Syria and toxic industrial chemicals in Iraq, as well as more targeted assassination operations in Malaysia and the United Kingdom, employing VX and novichok nerve agents, respectively. Concerns about such malign applications of chemical technology are exacerbated by the unstable international security environment and the changing nature of armed conflict, “where borderlines between war, civil war, large-scale violations of human rights, revolutions and uprisings, insurgencies and terrorism as well as organized crime are blurred” (1). It is thus essential that the global community regularly review the nature and implications of developments in chemistry, and its convergence with the life and associated sciences, and establish appropriate measures to prevent their misuse. With the parties to the Chemical Weapons Convention (CWC) convening a Review Conference to address such issues beginning 21 November 2018, we highlight important scientific aspects (2)

A holistic arms control (HAC) analytical framework was employed to explore the full range of mechanisms that could potentially be utilised to effectively regulate the development, stockpiling, transfer or use of riot control agents (RCAs), incapacitants and related means of delivery. From this analysis it is clear that the Chemical Weapons Convention (CWC) and its attendant regime are the most appropriate and probably the most receptive mechanisms, at least in the short term, for the discussion of these concerns and the development of appropriate policy responses. However, the response of CWC States Parties to these issues is by no means certain and parallel processes should be established to explore alternative regulatory mechanisms with the Biological and Toxin Weapons Convention, UN drugs conventions, international and regional human rights instruments, international humanitarian law, and transfer controls potentially yielding positive results in the next five to ten year period. Other regimes that may well prove important in the longer term include: the international criminal court and other international criminal law entities; the UN Secretary General¿s investigation mechanism and other ad hoc UN investigatory mechanisms. A comprehensive HAC strategy for the regulation of RCAs, incapacitants and related means of delivery will also require active involvement of informed and activist civil society in societal verification; development and promotion of norms prohibiting the involvement of scientific and medical communities in weaponisation programmes intended for malign application; and far greater active engagement of such expert communities in relevant State and international policy development processes.

No / This article explores the implications for human rights and human security arising from the development and use of weapons employing certain toxic chemicals, termed incapacitating chemical agents (ICAs), ostensibly intended for law enforcement operations. Publicly accessible information clearly indicates that China, Israel and the Russian Federation have acquired or developed ICA weapons, and that such weapons are either in the possession, or have been used by law enforcement or security services, of those countries since the coming into force of the Chemical Weapons Convention (CWC) in 1997. Although there is evidence of potentially applicable dual-use research in additional states, the full nature and purpose of such research, in certain states, is unclear as are the intended applications to which it will be put. Following a survey of state practice, existing obligations upon states derived from relevant international law are examined, specifically the CWC and applicable human rights instruments. Whilst existing international law certainly severely constrains and arguably prohibits the development, acquisition and use of such weapons for law enforcement, there are areas of contested interpretation, which need to be urgently addressed by the international community.

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Yes / In this report, we identify some of the key technical and political challenges currently facing the broader Chemical and Biological Weapon (CBW) regime- with a particular emphasis on major forthcoming diplomatic meetings. Most significantly the Ninth Review Conference of the Biological and Toxins Weapons Convention (1972) (BTWC) which will take place in 2022 and preparations for the Fifth Review Conference of the Chemical Weapons Convention (1993) (CWC), expected in 2023. This report is an output of an ongoing project, designed to stimulate thinking and discussion about these issues, within relevant stakeholder communities. The report provides an introduction to this issue area for the general reader before surveying key issues and developing a series of practical policy suggestions for further consideration.