With economic sustainable development and improvement of the living standard, China insurance industry has been developed quickly as the result of reforms and development of national economy since 1980. The average annual rate of growth nearly reached 30%. The premium income of whole insurance industry are about 564,140 million RMB, and total assets about 1.97 trillion RMB in year 2006. The differences in regional GDP and personal income as its uneven distribution of natural resources and economic inequalities caused. It is also caused uneven development of the Chinese insurance industry nationwide. This study refers to the report of the State Council of China as indicated 4 major economic areas that 1. The North-East region: to revitalizing the old industrial base. 2. The Western region: to implementing the great development as blueprint by government. 3. The Central region: to promoting as key position of economy development. 4. The East region: encouraged to take the leading position in order to implementing policy of central government, etc. To submitted regional strategy of insurance operations in China, the study also refers the dissertations of the domestic and international scholarship with analytic approach of SWOT, analysis of covariance and Chi-Square test. And also carries the directive analysis and the summary of operational strategy of insurance business. It is also concluded that along with the individual income increase will resulting service demand widely. Key words: China Economy, China Insurance Industry, Regional Strategy.