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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Chlamydia trachomatis in university women an epidemological study

Hietpas, Kristine Kratzer. 1980 (has links)
Thesis (M.S.)--University of Wisconsin-Madison. Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 61-65).
2

Modulation of interferon-gamma receptor expression during infection with Chlamydia psittaci 6bc and its influence on indoleamine 2,3-dioxygenase

Shirey, Kari Ann. 2006 (has links)
Thesis (Ph. D.)--Miami University, Dept. of Microbiology, 2006. Title from second page of PDF document. Document formatted into pages; contains [3], vi, 176 p. : ill. Includes bibliographical references (p. 131-176).
3

Studies in DNA immunization

Svanholm, Cecilia 1999 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst. Härtill 4 uppsatser.
4

Funktionelle Proteomanalyse von Chlamydophila pneumoniae

Wehrl, Wolfgang. 2004 (has links)
Berlin, Freie Universiẗat, Diss., 2005. Dateiformat: zip, Dateien im PDF-Format.
5

The use of magnetic resonance imaging to evaluate Chlamydia as an aetiological agent in Alzheimer's disease

Szczerba, Stephen Michael 24 August 2009 (has links)
It has been suggested that infection with Chlamydia may play a role in the initiation/progression of Alzheimer’s disease (AD). To evaluate this hypothesis APP/PS transgenic mice (genetically manipulated to express AD pathology) and wild type (Wt) mice were infected with C. muridarum, and magnetic resonance imaging (MRI) and histopathology were used to assess pathological changes. Congo red staining of tissue sections demonstrated no AD plaque pathology in Wt infected and non-infected mice, while clear pathology (neuritic plaques) was seen in transgenic mice, with a trend towards higher plaque counts in the brains in the infected transgenic mice. When MRI was used to evaluate the effects of infection in vivo, hyperintensities in T2 times were observed in APP/PS infected mice compared to APP/PS control mice both at month 5 and month 20. Together these results suggest that infection with Chlamydia may accelerate the development of AD.
6

The use of magnetic resonance imaging to evaluate Chlamydia as an aetiological agent in Alzheimer's disease

Szczerba, Stephen Michael 24 August 2009 (has links)
It has been suggested that infection with Chlamydia may play a role in the initiation/progression of Alzheimer’s disease (AD). To evaluate this hypothesis APP/PS transgenic mice (genetically manipulated to express AD pathology) and wild type (Wt) mice were infected with C. muridarum, and magnetic resonance imaging (MRI) and histopathology were used to assess pathological changes. Congo red staining of tissue sections demonstrated no AD plaque pathology in Wt infected and non-infected mice, while clear pathology (neuritic plaques) was seen in transgenic mice, with a trend towards higher plaque counts in the brains in the infected transgenic mice. When MRI was used to evaluate the effects of infection in vivo, hyperintensities in T2 times were observed in APP/PS infected mice compared to APP/PS control mice both at month 5 and month 20. Together these results suggest that infection with Chlamydia may accelerate the development of AD.
7

Detección de Neisseria gonorrhoeae y Chlamydia trachomatis en hombres que tienen sexo con hombres (HSH) mediante la prueba de Amplificación Mediada por Transcripción de ácido ribonucleico, Epicentro, Lima 2013 - 2014

Vásquez Vásquez, Francesca Rosalía de María 2016 (has links)
Determina la frecuencia de N. gonorrhoeae y C. trachomatis anal en HSH usando Amplificación Mediada por Transcripción (TMA) en muestras de hisopado anal. El método de Amplificación Mediada por Transcripción (TMA) tiene la capacidad de detectar pequeñas cantidades de ARN ribosomal (ARNr) de N. gonorrhoeae y C. trachomatis. Este estudio es imperioso ya que existe una alta frecuencia de contagio de ITS en la población de estudio, para lo cual el uso de TMA en pacientes con infecciones asintomáticas permitiría una detección adecuada y oportuna evitando así la diseminación de estas enfermedades a otros sujetos. Tesis
8

Dépistage systématique de l'infection uro-génitale à Chlamydia trachomatis chez les femmes de moins de 25 ans consultant au Centre d'Orthogénie du CHU de Nantes enquête sur 315 femmes

Fromion-Folliot, Gaëlle Meslé, Bernard 2005 (has links) (PDF)
Thèse d'exercice : Médecine. Médecine générale : Université de Nantes : 2005. Bibliogr. f. 75-81 [60 réf.].
9

Chlamydiae under stress : environmental conditions influence the production and localization of chlamydial antigens

Brown, Wendy J. 28 June 2002 (has links)
Chlamydiae are obligate intracellular pathogens that cause several serious conditions within the human host. Many of the symptoms associated with infection are thought to stem from the development of aberrant, or persistent, chlamydiae. Factors leading to chlamydial persistence include deprivation of amino acids, the release of certain cellular factors, or the addition of inhibitors of bacterial cell wall or DNA synthesis. Such changes within the chlamydial environment often lead to modifications in cell morphology, gene expression, chlamydial development, and antigen localization. In this report, I examine changes in antigen production and localization in Chlamydia-infected cells cultured in the presence of environmental stressors. There are three major areas of chlamydial biology examined: 1) how do the chlamydiae divide in the absence of FtsZ, 2) what is the importance of the predicted peptidoglycan hydrolase, PapQ; 3) what changes occur in antigen production and localization during the development of chlamydial persistence. One significant nonproteinacious factor apparently involved in chlamydial division is the SEP (septum) antigen, which localizes to the midcell of dividing chlamydiae. Non-dividing forms, such as persistent chlamydiae and EB, lack the septal placement of SEP, further suggesting the involvement of SEP in RB division. The production of the predicted hydrolase, PapQ, localizes to the cytosol of RB and, to a limited extent, within the EB. PapQ begins to accumulate as early as 12 hours after infection and during the time of RB-EB transition, an additional, smaller PapQ product accumulates. Ampicillin and tetracycline treatment inhibits accumulation of the smaller product suggesting that PapQ may be processed by a late expressed protease. This may have significance in RB-EB transition. The IncA-laden fibers protruding from the inclusion and into the host cytosol colocalize with a variety of different antigens that are generally restricted to the chlamydial outer membrane. Changes in culture conditions leads to changes in the amount and type of antigens localizing within the fibers. Chlamydial persistence dramatically influences the production and localization of several chlamydial antigens, creating significant changes in chlamydial cell biology that may enhance survival within the host. Graduation date: 2003
10

Infecção genital por Clhamydia Trachomatis em gestantes : prevalência e fatores associados Genital infection for clhamydia trachomatis in gestantes : prevalência and factors associates

Ibiapina, Flavio Lucio Pontes 2008 (has links)
IBIAPINA, Flávio Lúcio Pontes. Infecção genital por Clhamydia trachomatis em gestantes : prevalência e fatores associados. 2008. 73 f. Dissertação (Mestrado em Tocoginecologia) - Universidade Federal Ceará. Faculdade de Medicina, 2008. Submitted by denise santos (denise.santos@ufc.br) on 2012-10-22T13:18:52Z No. of bitstreams: 1 2008_dis_flpibiapina.pdf: 217559 bytes, checksum: c74eced6e1e5dd1db0e1078e37ef23d1 (MD5) Approved for entry into archive by Erika Fernandes(erikaleitefernandes@gmail.com) on 2012-10-26T15:11:52Z (GMT) No. of bitstreams: 1 2008_dis_flpibiapina.pdf: 217559 bytes, checksum: c74eced6e1e5dd1db0e1078e37ef23d1 (MD5) Made available in DSpace on 2012-10-26T15:11:52Z (GMT). No. of bitstreams: 1 2008_dis_flpibiapina.pdf: 217559 bytes, checksum: c74eced6e1e5dd1db0e1078e37ef23d1 (MD5) Previous issue date: 2008 To estimate the prevalence of Chlamydia trachomatis in pregnant women, comparing the positive group to the negative one in respect to socio-demographic factors, gynecologic history and exam, evaluating the risk factors associated to Chlamydia trachomatis genital infection. Subjects and methods: Hybrid capture test for Chlamydia trachomatis was performed in 446 pregnant women at Hospital Geral Dr César Cals, from the Health Secretary of the State of Ceará, from August, 2003 to May, 2004. Medium age in the group was 25.98 years and 19 weeks was the medium age of pregnancy. A structured questionnaire was applied, no matter the age of pregnancy, whether they were or not symptomatic, excluding those who had used antibiotics or any other substance into the vagina, during the previous fifteen days or who had kept sexual relationship until two days before the consultation, with a endocervical swab being performed, in order to have a hybrid capture test for the presence of Chlamydia trachomatis, as indicated by the manufacturer. Data were analysed by STATA 13.0, performed by means of the qui-square and logistic regression tests with descriptive and analytic presentation. Results: The prevalence of Chlamydia trachomatis among the pregnant women was 2.91%. Risk factors independently associated to Chlamydia trachomatis genital infection were history of pelvic pain or pelvic inflammatory disease, vulvar discharge and not using condom with an eventual sex partner. Respective odds ratio and confidence intervals were calculated to these variable. Conclusions: The positive group was younger, had smaller salaries and presented a greater frequency of divorced women, with less preservative use and more positive history of genital discharge and pelvic pain in the past. The OR to the presence of Chlamydia trachomatis genital infection was 1, 7 for those women not using condom and 0, 10 and 0, 17, respectively for a negative history of pelvic pain / PID, and the absence of vulvar discharge. determinar a prevalência de infecção genital por Chlamydia trachomatis em gestantes, comparando o subgrupo com diagnóstico positivo com o de diagnóstico negativo quanto aos fatores bio-sócio-demográficos, história ginecológica e exame físico ginecológico, avaliando-se os fatores associados à presença de infecção genital por Chlamydia trachomatis. Sujeitos e métodos: submeteram-se ao teste de captura híbrida para Chlamydia trachomatis 446 gestantes do ambulatório de pré-natal do Hospital Geral Dr César Cals, da Secretaria Estadual de Saúde-Ceará, no período de Agosto de 2003 a Maio de 2004. A idade média do grupo foi de 25,98 anos, idade gestacional média de 19 semanas. Aplicou-se questionário diretamente às gestantes, independente da idade gestacional e de estarem sintomáticas ou não, excluindo-se aquelas que tivessem feito uso de antibióticos ou de qualquer substância química intravaginal nos quinze dias anteriores à coleta, ou que tivessem mantido relações sexuais nos dois dias anteriores à consulta de pré-natal, com coleta de swab endocervical para realização de teste de captura híbrida II, com material colhido em tubo com solução conservadora utilizando o sistema de micro placa, conforme procedimento descrito pelo fabricante. Os dados foram analisados utilizando o software STATA 13.0, procedendo-se análise descritiva e analítica através do teste de qui-quadrado e regressão logística, subtraindo-se variáveis. Resultados: A prevalência de Chlamydia trachomatis entre as gestantes foi de 2.91%. Identificou-se como fatores de risco independentemente associados à infecção genital por Chlamydia trachomatis a história de dor pélvica ou doença inflamatória pélvica, presença de corrimento vulvar ao exame físico e não uso de preservativo com parceiro eventual. Calculou-se o Odds-ratio (OR), para cada um destes fatores, com respectivos intervalos de confiança. Conclusões: O subgrupo com rastreamento positivo para Chlamydia trachomatis caracterizou-se por apresentar uma faixa etária e renda familiar menor que o subgrupo com sorologia negativa, além de apresentar maior frequencia de pacientes separadas, que usam menos preservativos com parceiros eventuais e com mais antecedentes de corrimento genital e dor pélvica. A OR para presença de infecção genital por Chlamydia trachomatis foi de 1,7 para aquelas que não usam preservativos e foi de 0,10 e 0,17, respectivamente, para ausência de dor pélvica/DIP e corrimento vulvar.

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