The purpose of this review of literature is for nurses to understand and utilize sensory stimuli and the impact it has on infant cognition. Emphasis will be placed on the usage of visual, auditory and tactile stimulation on the cognitive development of infants between the ages of O and 6 months based on Piaget's theory of sensorimotor cognition. Introductory passages will focus on the developing brairi from birth until 6 months of age when the peak of myelation occurs. Initiating sensory stimulus during this period of time can ultimately create a positive impact on the growing brain by utilizing the myelation peak. This review will also present possible clinical application for nurses to implement in inpatient hospital settings along with parental education on the possible methods to utilize the findings and implications of this research. Further findings have found that infants respond most effectively to the combination of various stimuli than with one stimulus alone. Utilizing the findings found within the literature may hopefully help provide the evidence needed to support the clinical practice of these results. This research will be conducted through medical and nursing databases with conceptual primary sources that will further expand upon the selected studies on this topic.