The diploma thesis "Health and Socio-economic Indicators - reliability and validity testing of the PSAS" deals with a theoretical concept of health and its socio-economic indicators. A substantial part of the work concentrates on the application of PSAS tools to the Czech population and determining whether the range is reliable and valid for Czech respondents. To determine the reliability, a complex test is used for the whole range through the value of Cronbach's Alpha, and then the Item Response Theory (IRT) is also tested. The IRT test is done using the 18-point Likert's range of responses, of which is the PSAS composed. The validity is tested based on confirmatory factor analysis, using the construct validity as well as analysis of cognitive interviews for face validity. The secondary data analysis is done in SPSS, MPLUS, R, and IRTPRO programs. The last two programs are used to test the lesser known Item Response Theory.