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The effect of a diminished folate status on colorectal carcinogenesis /Le Leu, Richard Kevin. January 2000 (has links) (PDF)
Thesis (Ph.D.) -- University of Adelaide, Dept. of Medicine, 2000. / Errata pasted onto t.p. verso. Bibliography: leaves 129-148.
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Study of the role of [beta]-adrenoceptors in the promotion of colon cancer growth /Wong, Pui-shan, Helen. January 2007 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2008. / Also available online.
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Study of the role of [beta]-adrenoceptors in the promotion of colon cancer growthWong, Pui-shan, Helen. January 2007 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2008. / Also available in print.
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The LOX and LOXL2 amine oxidases in colon and esophageal cancerFong, Sheri F. T. January 2003 (has links)
Thesis (Ph. D.)--University of Hawaii at Manoa, 2003. / Includes bibliographical references (leaves 184-233).
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Effect of back raspberry extracts on colon cancer cell proliferationJohnson, Jodee Lee, January 2009 (has links)
Thesis (M.S.)--Ohio State University, 2009. / Title from first page of PDF file. Includes vita. Includes bibliographical references (p. 73-79).
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The effects of dietary factors on mutation dietary restriction and a Western diet /Hernańdez, Lya G. January 2003 (has links)
Thesis (M. Sc.)--York University, 2003. Graduate Programme in Biology. / Typescript. Includes bibliographical references (leaves 91-105). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://wwwlib.umi.com/cr/yorku/fullcit?pMQ82926.
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A histological and ultrastructural morphometric assessment of malignant potential in human colorectal epithelium /Tipoe, George Lim. January 1993 (has links)
Thesis (Ph. D.)--University of Hong Kong, 1994. / Includes bibliographical references (leaves 257-287).
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Morphometric and AgNOR studies of normal, transitional and malignant human colorectal epithelium /Morais, Marina. January 1994 (has links)
Thesis (M. Phil.)--University of Hong Kong, 1994. / Includes bibliographical references (leaves 208-230).
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The mechanism by which retinol decreases ß-catenin protein in retinoic acid-resistant colon cancer cellsDillard, Alice Clare, January 1900 (has links)
Thesis (Ph. D.)--University of Texas at Austin, 2007. / Vita. Includes bibliographical references.
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治療結腸癌的中藥考證鄭曉朦, 11 June 2016 (has links)
研究目的:結腸癌是現今最常見的惡性腫瘤之一。在西方國家, 其發病率甚至居惡性腫瘤的第二位,在我國發病率居第四位,並且發病率在不斷攀升。在長江中下游,江淅地區,福建,香港等較為發達地區發病率較高,研究提示可能與經濟發達、生活習慣以及飲食習慣有密切關係。隨著醫療技術的進步,西醫針對結腸癌已有多種治療手段。其中,于術治療、放化療綜合治療是主要的治療手段。但在一定程度上對患者機體有一定的毒副作用,嚴重影響生活品質,並且復發和轉移率較高。研究者發現一些中藥對結腸癌細胞有抑制細胞生長、影響腫瘤細胞相關資訊表達、抑制腫瘤細胞血管生成、誘導腫瘤細胞凋亡、對信號轉導通路的影響等作用。中草藥毒副作用小,成本低廉,提高患者生活品質,降低復發和轉移率。因此,中藥對結腸癌的抑制作用有較高的研究價值。 研究方法:選取人結腸癌HCTl 16 細胞用McCoys 5A 的細胞培養液放置於37 ℃、C02 體積分數為5%的培養箱中靜置培養。研究藥物選擇首先對結腸癌進行中醫辨證,分析每種證型用藥特點。其次在中國期刊全文資料庫進行關於結腸癌文獻檢索,在檢索結果中找出辨證分析中藥物出現頻率較高的。最後,查找相關碩士、博士論文以及有關結腸癌書籍資料篩選出以下幾種進行考證對結腸癌細胞是否有抑制作用的中草藥。(土茯苓、白花蛇古草、馬齒莧、藤梨根、敗醬草、白頭翁) 。分別用DCM 以及MEOH 提取土茯苓、白花蛇古草、馬齒莧、藤梨根、敗醬草、白頭翁,將培養好的細胞種植在96 孔板上,分別加入上述藥物提取物。用SRB 法檢測細胞的增殖情況。 研究結果: 根據實驗所得數據發現, 其中茯夜苓、和敗醬草的DCM 提取液均對HCT116細胞有較強的抑制作用,白花蛇古草對此種結腸癌細胞雖有抑制細胞增殖的作用,但結果並不明顯,實驗所得結果還有待反復實驗,以及進一步探究作用機制。然而藤梨根、馬齒莧、白頭翁的DCM 提取液以及用MEOH 提取的上述藥物均對細胞HCT116 無明顯抑制作用, 考慮實驗僅對單一細胞進行,檢測藥物提取物作用於HCT116 細胞的抑制性 。因此, 本實驗僅為六種中草藥提純物對HCT l 16 細胞的抑制作用初步探究,還有待進一步深入研究。
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