Purpose: To examine the relationship between visual acuity (VA) and radial deformation acuity (RDA) in children 6 to 12 years of age with amblyopia. Methods: RDA was measured in 35 participants with the Manchester RDA charts. VA was measured with the Early Treatment Diabetic Retinopathy Research Study (ETDRS) chart. Results: Median VA in non-amblyopic and amblyopic eyes was 0.04 logMAR (IQF -0.06 – 0.12) and 0.24 (IQF 0.12 – 0.04), respectively (Wilcoxon Signed Ranks test, z = -5.07, p < 0.001). Median RDA in non-amblyopic and amblyopic eyes was 2.73 log (IQF 2.53 – 2.87) and 2.63 log (IQF 2.53 – 2.77), respectively (Wilcoxon, z = -2.56, p < 0.05). Spearman correlation suggested that the amblyopic deficits in VA and RDA were related, r = -0.42, p < 0.05. Conclusion: A deficit in RDA was present in most children with amblyopia. A moderate relationship was noted between the amblyopic deficits found in VA and RDA.

Thesis (Ph.D.)--University of Western Australia, 2003.

Thesis (M.S.)--Virginia Polytechnic Institute and State University, 1994. / Vita. Abstract. Includes bibliographical references (leaves 34-38). Also available via the Internet.

Issued also as author's dissertation. / Columbia contributions to philosophy and psychology, vol. XX, no. 2.

M. Phil. / Please refer to full text to view abstract / Prof. J.T. Ferreira

No description available.

Clinical relevance: Mobility and fall risk may be important considerations in choosing between intraocular lenses. Background: Fall risk in older adults increases when wearing multifocal spectacles, but little is known about mobility among individuals with different types of intraocular lenses. This study compared visual function, fall risk and balance control following bilateral implantation of monofocal or multifocal intraocular lenses. Methods: This was a non-randomised, cross-sectional study involving adults with bilateral intraocular lenses. Participants completed questionnaires concerning physical functioning, fall history and balance-related confidence. Binocular visual acuity, contrast sensitivity (Pelli-Robson chart and computerized testing), depth perception and glare sensitivity were assessed. Physical performance measures included the Sensory Organization Test, preferred gait speed, Dynamic Gait Index and wayfinding in a virtual environment. Results: Fifteen participants (mean ± standard deviation, 67.1 ± 6.8 years) had monofocal intraocular lenses and 14 participants (68.1 ± 6.1 years) had multifocal intraocular lenses. Contrast sensitivity in the monofocal group was significantly better than that in the multifocal group (p = 0.02) at intermediate and high spatial frequencies. Contrast sensitivity of the monofocal group also was less affected by glare than the contrast sensitivity of the multifocal group, at an intermediate spatial frequency (p = 0.02). However, the multifocal group had significantly better Dynamic Gait Index scores (p = 0.04), even after controlling for perceived physical function. Conclusions: The participants with monofocal intraocular lenses generally had better contrast sensitivity than did those with multifocal intraocular lenses. However, the scores on a mobility test that is associated with fall risk were worse for those with monofocal lenses.

Static Visual Acuity (SVA) has been called into question for some time as a measure of overall visual system function and as a predictor of performance on real-life tasks requiring vision (i.e., operating an automobile). Specifically, it has been pointed out that the targets employed in most SVA testing (high contrast, stationary letters) are an insufficient analog to actual targets encountered in everyday activities, which are often in motion and/or of less-than-perfect contrast. In addition, the size-threshold methodology typically used to measure SVA is incongruent with current theories of a multi-channel visual system. Dynamic Visual Acuity (DVA) and Contrast Sensitivity have been suggested as alternatives to SVA, but while each mitigates specific weaknesses of the SVA measure, neither addresses the shortcomings completely. Traditional DVA measures employ moving targets, but these targets are usually of perfect contrast and a size-threshold methodology is used to specify acuity levels. Contrast Sensitivity employs a contrast-threshold methodology and allows measurement of specific visual channels, but stationary targets are utilized. The present study combined the DVA and Contrast Sensitivity measures in an effort to retain the unique qualities of each while addressing their shortcomings, resulting in a more detailed picture of the human visual system and functioning than has yet been possible. By measuring contrast sensitivity to targets at a set of spatial frequencies spanning the human "window of visibility" and under conditions of motion representative of that encountered in everyday activities, it was hoped that a more powerful predictor of actual visual performance would be created. In addition, normative data was established for two separate age populations, in the hopes of learning more about specific changes that occur to the visual system during the aging process. Indeed, several effects and interactions among the three main variables (spatial frequency, velocity, age) were uncovered, which appears to indicate that the new test may provide more information about the visual system than DVA or contrast sensitivity by themselves. The ramifications of this effort to human factors and visual performance research are discussed along with recommendations for the continuation and application of this line of research.

No / The spatial and temporal properties of human colour vision are examined using isoluminant, red¿green and blue¿yellow tritanopic gratings. Chromatic sensitivity is found to be low-pass as a function of both spatial and temporal frequency along all the chromatic axes investigated, including the tritanopic confusion lines employed to examine the properties of the S-cone driven mechanism. Comparison of sensitivity to on-off and contrast reversing stimuli indicates that transient mechanisms contribute to the detection of red¿green patterns but that the detection of S-cone specific patterns is governed by sustained mechanisms. By compensating for transient contributions to red¿green sensitivity, it is shown that sensitivity of chromatic mechanisms dominated by L- and M-cone input are closely matched to those with S-cone input.

Yes / Purpose: Even during steady fixation, people make small eye movements such as microsaccades, whose rate is altered by presentation of salient stimuli. Our goal was to develop a practical method for objectively and robustly estimating contrast sensitivity from microsaccade rates in a diverse population. Methods: Participants, recruited to cover a range of contrast sensitivities, were visually normal (n = 19), amblyopic (n = 10), or had cataract (n = 9). Monocular contrast sensitivity was estimated behaviorally while binocular eye movements were recorded during interleaved passive trials. A probabilistic inference approach was used to establish the likelihood of observed microsaccade rates given the presence or absence of a salient stimulus. Contrast sensitivity was estimated from a function fitted to the scaled log-likelihood ratio of the observed microsaccades in the presence or absence of a salient stimulus across a range of contrasts. Results: Microsaccade rate signature shapes were heterogeneous; nevertheless, estimates of contrast sensitivity could be obtained in all participants. Microsaccade-estimated contrast sensitivity was unbiased compared to behavioral estimates (1.2% mean), with which they were strongly correlated (Spearman's ρ 0.74, P < 0.001, median absolute difference 7.6%). Measurement precision of microsaccade-based contrast sensitivity estimates was worse than that of behavioral estimates, requiring more than 20 times as many presentations to equate precision. Conclusions: Microsaccade rate signatures are heterogeneous in shape when measured across populations with a broad range of contrast sensitivities. Contrast sensitivity can be robustly estimated from rate signatures by probabilistic inference, but more stimulus presentations are currently required to achieve similarly precise estimates to behavioral techniques. / Supported by a Confidence in Concept grant from the Medical Research Council, a Fight for Sight Project Grant (5059/5060) and a Wellcome Trust Research Fellowship to NWR (WT097387).