OBJECTIVE: This case series evaluated the vision and refractive outcomes of patients who underwent Raindrop corneal inlay removal with or without concomitant LASIK treatment. METHODS: This study utilized a case series design and a retrospective data review of electronic medical records from a private ophthalmology clinic in Boston, MA. Twenty-one patients who had a Raindrop inlay placed and subsequently removed were identified. To be included in the study, patient records had to contain vision and refraction measurements from (1) before Raindrop inlay placement, (2) before Raindrop inlay removal, and (3) at least 1 month after Raindrop inlay removal. Fifteen patients with the necessary records were included in the study. Of these 15 patients, 7 had Raindrop inlays removed and the remaining 8 had Raindrop inlays removed with concomitant LASIK treatment. RESULTS: Fourteen of the 15 total patients had a best-corrected distance vision of 20/20 or better prior to inlay placement. This study found that 10 of these 15 patients experienced a loss of at least 1 line of best-corrected distance vision by the time of inlay removal. Inlay removal was performed at a mean of 523 days, or approximately 17 months, after placement. Even after inlay removal (>6 weeks), 7 patients continued to sustain a loss of 1 or more lines of best-corrected distance vision. In patients receiving LASIK at or after the time of inlay removal, the refractive outcome was close to target in only one case. CONCLUSION: After Raindrop inlay removal, many patients experience an improvement in their vision compared with pre-explantation; however, their best-corrected distance vision may not immediately return to preoperative values. Corneal haze and inflammation may continue to persist post-explantation and affect measurements of refractive error. Concomitant LASIK treatment upon inlay removal may therefore fail to achieve the intended result of monovision as an alternative treatment for presbyopia.