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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Randomization test and correlation effects in high dimensional data

Wang, Xiaofei January 1900 (has links)
Master of Science / Department of Statistics / Gary Gadbury / High-dimensional data (HDD) have been encountered in many fields and are characterized by a “large p, small n” paradigm that arises in genomic, lipidomic, and proteomic studies. This report used a simulation study that employed basic block diagonal covariance matrices to generate correlated HDD. Quantities of interests in such data are, among others, the number of ‘significant’ discoveries. This number can be highly variable when data are correlated. This project compared randomization tests versus usual t-tests for testing of significant effects across two treatment conditions. Of interest was whether the variance of the number of discoveries is better controlled in a randomization setting versus a t-test. The results showed that the randomization tests produced results similar to that of t-tests.

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