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Versuche zur ersten Totalsynthese des Aglycons der Cripowelline A und B und erste asymmetrische Synthese von TropionalBackes, Michael. January 2004 (has links)
Aachen, Techn. Hochsch., Diss., 2004. / Computerdatei im Fernzugriff.
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Versuche zur ersten Totalsynthese des Aglycons der Cripowelline A und B und erste asymmetrische Synthese von TropionalBackes, Michael. Unknown Date (has links) (PDF)
Techn. Hochsch., Diss., 2004--Aachen.
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Asymmetrische Synthesen von Attenol A und B, (+)-Strictifolion und des 1-epi-Aglycons der Cripowelline A und BLenzen, Achim. Unknown Date (has links) (PDF)
Techn. Hochsch., Diss., 2005--Aachen.
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Isolation, Structure Elucidation, and Total Synthesis of Biologically Active Natural Products from PlantsPresley, Christopher Charles 06 November 2017 (has links)
As a part of the continuing search for bioactive compounds with the Madagascar International Cooperative Biodiversity Group (ICBG), and in collaboration with the Natural Products Discovery Institute of the Institute for Hepatitis and Virus Research (IHVR), thirteen plant extracts were investigated for antiplasmodial activity, thirteen plant extracts were investigated for antiproliferative activity, and one extract was investigated for inhibitors of the shikimate pathway in Plasmodium falciparum. Bioassay-guided fractionation of the extracts led to the identification of nineteen compounds with both antiplasmodial and antiproliferative activity, and thirteen compounds with only antiproliferative activity. Thirteen of these compounds (2.1 – 2.9, 3.3, 3.4, 4.5, and 5.1) were previously unknown. In addition total synthesis was used to confirm the structure of one new compound (4.5) and two other new natural-product like compounds (4.6 and 4.7) were also synthesized and investigated for antiplasmodial activity. / Ph. D.
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