We propose a synthesis methodology for Network-on-Chips (NoC) or NoC-based multiprocessor systems-on-chip (MPSoCs) for application-specific or irregular topology generation.We first propose simultaneously synthesize both for processor and communication architectures in order to estimate area and routing more accurately during floorplanning stage, which is different with traditional router and link insertion after floorplanning. Our NoC topology generation is simultaneously optimized for fast, low power and wirelength. Compared with the state of art, our results outperforms averagely 445.45 X in CPU time, 33.20 % in power consumption, and 96.86 % in wirelength at cost of NoC Size of more 2.26 % because our method considering router shape; the number of routers of more 20.63 % because our method only allows router port limit of 5; the number of links of more 3.93 % because our method allows different link lengths. Also our method is scalable and experiments of 2 X, 4 X, 8 X and 16 X outperform averagely 355,089.11 X in CPU time, 1.21 X in the number hops, 78.33 % in power consumption. Our experimental results show our synthesis method is effective, efficiently and scalable.