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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
11

Analysis of the function of Drosophila cyclin E isoforms and identification of interactors

Crack, Donna. January 2002 (has links) (PDF)
"August 2002." Bibliography: p. 157-169. Analysis of the expression of Drosophilia cyclin EII through development show that it was present during larval development and oogenesis, implying a role for DmcycEII outside of early embyogenesis. Ectopic expression analyses using full-length DmcycE proteins as well as N- and C-terminal deletions of DmcycEI, revealed that DmcycEII and N-terminal deletions were able to drive all G1 cells within the morphogenetic furrow of the eye imaginal disc into S phase, while a C-terminal deletion of DmcycEI could not. These results show the DmcycEII is more potent than DmcycEI in driving cells into S phase and that the N-terminal region of DmcycEI contains a negative regulatory domean., suggesting that an inhibitor is present in the posterior morphogenetic furrow that binds to DmcycEI N-terminus and inhibits DmcycEI function. To identify the DmcycEI specific inhibitor, genetic interaction and yeast-2 hybrid screens were undertaken, and an enhancer CG7394, encoding a MAGUK homologue was identified for further study.
12

Analysis of the function of Drosophila cyclin E isoforms and identification of interactors / Donna Crack.

Crack, Donna January 2002 (has links)
"August 2002." / Bibliography: p. 157-169. / xi, 169 p. : ill. (some col.), plates (some col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Analysis of the expression of Drosophilia cyclin EII through development show that it was present during larval development and oogenesis, implying a role for DmcycEII outside of early embyogenesis. Ectopic expression analyses using full-length DmcycE proteins as well as N- and C-terminal deletions of DmcycEI, revealed that DmcycEII and N-terminal deletions were able to drive all G1 cells within the morphogenetic furrow of the eye imaginal disc into S phase, while a C-terminal deletion of DmcycEI could not. These results show the DmcycEII is more potent than DmcycEI in driving cells into S phase and that the N-terminal region of DmcycEI contains a negative regulatory domean., suggesting that an inhibitor is present in the posterior morphogenetic furrow that binds to DmcycEI N-terminus and inhibits DmcycEI function. To identify the DmcycEI specific inhibitor, genetic interaction and yeast-2 hybrid screens were undertaken, and an enhancer CG7394, encoding a MAGUK homologue was identified for further study. / Thesis (Ph.D.)--University of Adelaide, Dept. of Molecular Biosciences, 2002
13

The functional roles of cyclin-dependent kinase 5 in neural development /

Fu, Wing Yu. January 2002 (has links)
Thesis (Ph. D.)--Hong Kong University of Science and Technology, 2002. / Includes bibliographical references (leaves 154-172). Also available in electronic version. Access restricted to campus users.
14

Identification of Pctaire1 as a p35-interacting protein and a novel substrate for Cdk5 /

Cheng, Kai. January 2003 (has links)
Thesis (Ph. D.)--Hong Kong University of Science and Technology, 2003. / Includes bibliographical references (leaves 153-177). Also available in electronic version. Access restricted to campus users.
15

Identification of novel G1 to S phase regulators in Drosophila / by Julie Secombe.

Secombe, Julie January 1999 (has links)
Bibliography: p. 143-160. / 160 p., [66] leaves, [30] leaves of plates : ill. (some col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Focusses on identifying genes involved in the regulation of Cyclin E transcription or function during Drosophila development. / Thesis (Ph.D.)--University of Adelaide, Dept. of Chemistry, 1999
16

Identification of novel G1 to S phase regulators in Drosophila / by Julie Secombe.

Secombe, Julie January 1999 (has links)
Bibliography: p. 143-160. / 160 p., [66] leaves, [30] leaves of plates : ill. (some col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Focusses on identifying genes involved in the regulation of Cyclin E transcription or function during Drosophila development. / Thesis (Ph.D.)--University of Adelaide, Dept. of Chemistry, 1999
17

Synthesis of ring-constrained thiazolylpyrimidines : inhibitors of cyclin-dependent kinases /

McIntyre, Neil A. January 2007 (has links)
Thesis (Ph.D.) - University of St Andrews, January 2007. / Restricted until 30th January 2010.
18

Cell-cycle regulation by Cdk1 in Saccharomyces cerevisiae /

Ubersax, Jeffrey A. January 2004 (has links)
Thesis (Ph.D.)--University of California, San Francisco, 2004. / Bibliography: leaves 141-150. Also available online.
19

The functions and proteolysis of cyclin A and cyclin F during mitosis /

Fung, Tsz Kan. January 2006 (has links)
Thesis (Ph.D.)--Hong Kong University of Science and Technology, 2006. / Includes bibliographical references (leaves 197-228). Also available in electronic version.
20

Evaluation of the chicken cyclin-dependent kinase inhibitor 1B, p27(Kip1) in MDV-induced transformation

Kim, Sungwon. January 2007 (has links)
Thesis (M.S.)--University of Delaware, 2007. / Principal faculty advisor: Marlene G. Emara, Dept. of Animal & Food Sciences. Includes bibliographical references.

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