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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
41

Identification of meiotic regulatory targets of Ndt80 by biochemical and genetic analysis /

Jolly, Emmitt R., Jr. January 2004 (has links)
Thesis (doctoral in Biochemistry and Molecular Biology)--University of California, San Francisco, 2004. / Bibliography: leaves 80-88. Also available online.
42

Purification and biological properties of excretory/secretory antigens from trichinella spiralis /

Leung, Kin-ming, Rayman. January 1995 (has links)
Thesis (M. Phil.)--University of Hong Kong, 1995. / Includes bibliographical references (leaf 100-112).
43

Binding, bending and G jumping in the minor groove experimental and theoretical approaches /

Rahimian, Maryam. January 2008 (has links)
Thesis (Ph. D.)--Georgia State University, 2008. / Title from file title page. W. David Wilson, committee chair; David W. Boykin, Stuart A. Allison, Donald Hamelberg, committee members. Description based on contents viewed Aug. 20, 2009. Includes bibliographical references.
44

Genome-wide mapping of DNA-protein interactions in eukaryotes

Kim, Jonghwan, January 1900 (has links) (PDF)
Thesis (Ph. D.)--University of Texas at Austin, 2005. / Vita. Includes bibliographical references.
45

Identification and characterization of novel DNA replication-initiation proteins in budding yeast /

Huo, Lin. January 2006 (has links)
Thesis (Ph.D.)--Hong Kong University of Science and Technology, 2006. / Includes bibliographical references (leaves 148-167). Also available in electronic version.
46

An examination of homeodomains and their binding sites

陳雅莉, Chan, Nga-li, Celia. January 2001 (has links)
published_or_final_version / Biochemistry / Master / Master of Philosophy
47

Accurate and Sensitive Quantification of Protein-DNA Binding Affinity

Rastogi, Chaitanya January 2017 (has links)
Transcription factors control gene expression by binding to genomic DNA in a sequence-specific manner. Mutations in transcription factor binding sites are increasingly found to be associated with human disease, yet we currently lack robust methods to predict these sites. Here we developed a versatile maximum likelihood framework, named No Read Left Behind (NRLB), that fits a biophysical model of protein-DNA recognition to all in vitro selected DNA binding sites across the full affinity range. NRLB predicts human Max homodimer binding in near-perfect agreement with existing low-throughput measurements. The model captures the specificity of p53 tetrameric binding sites and discovers multiple binding modes in a single sample. Additionally, we confirm that newly-identified low-affinity enhancer binding sites are functional in vivo, and that their contribution to gene expression matches their predicted affinity. Our results establish a powerful paradigm for identifying protein binding sites and interpreting gene regulatory sequences in eukaryotic genomes.
48

In vitro and in vivo studies of DNA cleavage and targeted cleavage of HIV REV response element RNA by metallopeptides

Jin, Yan. January 2006 (has links)
Thesis (Ph. D.)--Ohio State University, 2006. / Available online via OhioLINK's ETD Center; full text release delayed at author's request until 2007 Aug 15.
49

Structural and dynamic basis for the cAMP-mediated allosteric control of the catabolite activator protein (CAP)

Popovych, Nataliya. January 2009 (has links)
Thesis (Ph. D.)--Rutgers University, 2009. / "Graduate Program in Chemistry." Includes bibliographical references (p. 147-163).
50

Detection of farnesyltransferase within single mammalian cells /

Pang, Zhulin. January 2008 (has links)
Thesis (M.Sc.)--York University, 2008. Graduate Programme in Biology. / Typescript. Includes bibliographical references (leaves 105-106). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:MR38818

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