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Identification of meiotic regulatory targets of Ndt80 by biochemical and genetic analysis /Jolly, Emmitt R., Jr. January 2004 (has links)
Thesis (doctoral in Biochemistry and Molecular Biology)--University of California, San Francisco, 2004. / Bibliography: leaves 80-88. Also available online.
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Purification and biological properties of excretory/secretory antigens from trichinella spiralis /Leung, Kin-ming, Rayman. January 1995 (has links)
Thesis (M. Phil.)--University of Hong Kong, 1995. / Includes bibliographical references (leaf 100-112).
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Binding, bending and G jumping in the minor groove experimental and theoretical approaches /Rahimian, Maryam. January 2008 (has links)
Thesis (Ph. D.)--Georgia State University, 2008. / Title from file title page. W. David Wilson, committee chair; David W. Boykin, Stuart A. Allison, Donald Hamelberg, committee members. Description based on contents viewed Aug. 20, 2009. Includes bibliographical references.
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Genome-wide mapping of DNA-protein interactions in eukaryotesKim, Jonghwan, January 1900 (has links) (PDF)
Thesis (Ph. D.)--University of Texas at Austin, 2005. / Vita. Includes bibliographical references.
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Identification and characterization of novel DNA replication-initiation proteins in budding yeast /Huo, Lin. January 2006 (has links)
Thesis (Ph.D.)--Hong Kong University of Science and Technology, 2006. / Includes bibliographical references (leaves 148-167). Also available in electronic version.
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An examination of homeodomains and their binding sites陳雅莉, Chan, Nga-li, Celia. January 2001 (has links)
published_or_final_version / Biochemistry / Master / Master of Philosophy
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Accurate and Sensitive Quantification of Protein-DNA Binding AffinityRastogi, Chaitanya January 2017 (has links)
Transcription factors control gene expression by binding to genomic DNA in a sequence-specific manner. Mutations in transcription factor binding sites are increasingly found to be associated with human disease, yet we currently lack robust methods to predict these sites. Here we developed a versatile maximum likelihood framework, named No Read Left Behind (NRLB), that fits a biophysical model of protein-DNA recognition to all in vitro selected DNA binding sites across the full affinity range. NRLB predicts human Max homodimer binding in near-perfect agreement with existing low-throughput measurements. The model captures the specificity of p53 tetrameric binding sites and discovers multiple binding modes in a single sample. Additionally, we confirm that newly-identified low-affinity enhancer binding sites are functional in vivo, and that their contribution to gene expression matches their predicted affinity. Our results establish a powerful paradigm for identifying protein binding sites and interpreting gene regulatory sequences in eukaryotic genomes.
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In vitro and in vivo studies of DNA cleavage and targeted cleavage of HIV REV response element RNA by metallopeptidesJin, Yan. January 2006 (has links)
Thesis (Ph. D.)--Ohio State University, 2006. / Available online via OhioLINK's ETD Center; full text release delayed at author's request until 2007 Aug 15.
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Structural and dynamic basis for the cAMP-mediated allosteric control of the catabolite activator protein (CAP)Popovych, Nataliya. January 2009 (has links)
Thesis (Ph. D.)--Rutgers University, 2009. / "Graduate Program in Chemistry." Includes bibliographical references (p. 147-163).
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Detection of farnesyltransferase within single mammalian cells /Pang, Zhulin. January 2008 (has links)
Thesis (M.Sc.)--York University, 2008. Graduate Programme in Biology. / Typescript. Includes bibliographical references (leaves 105-106). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:MR38818
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