To simplify the measurement of energy-based structural metrics, a general registration process for the scanning laser doppler vibrometer (SLDV) has been developed. Existing registration techniques, also known as pose estimation or position registration, suffer from mathematical complexity, instrument specificity, and the need for correct optimization initialization. These difficulties have been addressed through development of a general linear laser model and hybrid registration algorithm. These are applicable to any SLDV and allow the registration problem to be solved using straightforward mathematics. Additionally, the hybrid registration algorithm eliminates the need for correct optimization initialization by separating the optimization process from solution selection. The effectiveness of this approach is demonstrated through simulated application and by validation measurements performed on a specially prepared pipe. To increase understanding of the relationships between structural energy metrics and the acoustic response, the use of structural energy density (SED) in active structural acoustic control (ASAC) has also been studied. A genetic algorithm and other simulations were used to determine achievable reduction in acoustic radiation, characterize control system design, and compare SED-based control with the simpler velocity-based control. Using optimized sensor and actuator placements at optimally excited modal frequencies, attenuation of net acoustic intensity was proportional to attenuation of SED. At modal and non-modal frequencies, optimal SED-based ASAC system design is guided by establishing general symmetry between the structural disturbing force and the SED sensor and control actuator. Using fixed sensor and actuator placement, SED-based control has been found to provide superior performance to single point velocity control and very comparable performance to two-point velocity control. Its greatest strength is that it rarely causes unwanted amplifications of large amplitude when properly designed. Genetic algorithm simulations of SED-based ASAC indicated that optimal control effectiveness is obtained when sensors and actuators function in more than one role. For example, an actuator can be placed to simultaneously reduce structural vibration amplitude and reshape the response such that it radiates less efficiently. These principles can be applied to the design of any type of ASAC system.