Adoption of glyphosate-resistant crops has resulted in increased glyphosate usage and decreased use of residual herbicides thus resulting in weed pressure shifts. Weeds that display multiple-resistance to glyphosate and other herbicide modes of action have become a concern in many parts of the United States. Incorporation of multiple herbicide resistance traits into multiple cropping systems, may facilitate weed resistance to additional herbicides. Furthermore, controlling volunteer crop stands containing multiple herbicide-resistance traits may be problematic in herbicide resistant crops. These volunteer crops will compete with the currently growing crop qualifying them as a weed. Therefore, this research was conducted to determine control options for: failed glyphosate resistant corn stands, and volunteer glyphosate resistant corn stands in glyphosate resistant cotton. Furthermore, research was conducted to determine what densities of glyphosate-resistant corn will cause cotton yield loss and if time of removal of these densities impacts cotton yield loss.