The evidence suggesting Attention-Deficit/Hyperactivity Disorder (ADHD) has neurodevelopmental roots with specific impairment in executive functioning continues to grow. However, no known study to date has explored the relationship between adult males with a diagnosis of ADHD and performance on a measure of executive functioning, the Delis-Kaplan Executive Function System (DKEFS). The current investigation attempted to explore (1) whether adult males with ADHD show an overall pattern of executive dysfunction as measured by the DKEFS, (2) potential group differences on both level-of-performance and process-oriented measure scores, and (3) the clinical utility of the DKEFS in diagnosing ADHD in adult males. A sample of 37 adults with ADHD was compared to a community sample of equal size. Multivariate statistical analysis yielded significant group differences despite intellectual advantage by the study group. In addition, analysis of individual measures revealed patterns which were not initially predicted based upon current theories of ADHD. Overall, however, no clinically significant impairments emerged, as defined by scores at least one standard deviation below the mean. These findings and potential clinical implications are discussed with recommendations for future research.

Executive functioning is a multidimensional concept encompassing higher-order adaptive abilities, such as judgment, decision-making, self-monitoring, planning, and emotional regulation. Disruption in executive functioning often results in devastating impairments in vitally-important areas of life, such as one's ability to hold employment and maintain social relationships. Executive functions have been associated primarily with the prefrontal cortex. However, the nature and degree of the association between frontal lobe damage and performance on executive functioning tests remains controversial. Research suggests that the association may vary based on the specific location of damage within the prefrontal cortex, as well as the used measure of executive functioning. Few investigations have systematically addressed these variables. The current study employed the lesion method to investigate the relationship between performance on a battery of executive functioning tests and damage to specific regions of the prefrontal cortex. Three groups of participants with lesions in one of the locations of interest [ventromedial prefrontal (VMPC, n = 14), dorsolateral prefrontal (DLPC, n = 14), and non-frontal (n = 18)] were administered the Delis-Kaplan Executive Function System (D-KEFS, 2001), a comprehensive battery of executive functioning tests. Results revealed no statistically-significant differences between group performances on the D-KEFS primary measures. However, a qualitative analysis of the results revealed several meaningful group differences. It appears that some relationship exists between frontal lobe damage, particularly in the DLPC, and decreased performance on several executive functioning tests but further research overcoming the methodological limitations of most existing literature on this topic is needed to clearly resolve this issue.