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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
121

The HPLC separation and electrochemical detection of azo dyes and their degradation products

Camp, Sharon Kay Ritchie 05 1900 (has links)
No description available.
122

Chalcogenopyrylium Dyes as Modulators of Multidrug Resistance Protein (MRP) 1, MRP2 and MRP4 Transport Activities

MYETTE, ROBERT LEONARD 29 November 2011 (has links)
MRPs mediate the ATP-dependent efflux of a structurally diverse array of compounds. Certain MRPs, including MRP1, MRP2 and MRP4, are involved in multidrug resistance in tumour cells, while in non-malignant cells these MRPs can influence the distribution and/or elimination of many clinically important drugs. In addition, these MRPs mediate the efflux of physiological metabolites, many of which are conjugated organic anions. Modulation of the drug transporting activity of MRP1 (and to a lesser extent MRP2 and MRP4) has been a long sought after therapeutic objective. In this study, the modulatory abilities of five structurally distinct classes (I-V) of chalcogenopyrylium dyes (CGPs) were examined utilizing an in vitro assay which measures inhibition of radiolabeled estradiol glucuronide ([3H]E217βG) (a prototypical MRP substrate) uptake into inside-out membrane vesicles prepared from MRP-transfected human embryonic kidney (HEK) cells. Additionally, some CGPs were tested in a calcein efflux assay using intact MRP1-transfected HEK cells. Sixteen of 34 CGPs initially tested at a single concentration (≤30 μM) inhibited MRP1-mediated uptake by >50%, with IC50’s ranging from 0.7-7.6 μM. Of the 9 CGPs with IC50’s ≤2 μM, five belonged to Class I, two to Class II, and two to Class IV. When tested in the calcein efflux assay, only 4 of 16 CGPs inhibited MRP1-mediated cellular efflux by >50% (I-3, -4, -6, IV-1) while a fifth (II-5) inhibited efflux by 23%. These five CGPs were then tested as modulators of [3H]E217βG uptake by MRP2 and MRP4. Their effects on MRP2 transport activity were differential with two (I-4, I-6) inhibiting transport (IC50’s 2.0, 7.1 μM), two (I-3, IV-1) stimulating transport (>2-fold), while II-5 had no effect. On the other hand, all five CGPs inhibited [3H]E217βG uptake by MRP4, but less effectively than by MRP1. Finally, five analogs of CGP IV-1 were tested for their effects on MRP1, MRP2 and MRP4 [3H]E217βG uptake, but none were more efficacious than CGP IV-1. The CGPs tested here represent novel MRP1, MRP2 and MRP4 modulators with variable effects on transport activities. These CGPs may represent a new avenue for the development of clinically applicable modulators of MRP proteins involved in multidrug resistance. / Thesis (Master, Pathology & Molecular Medicine) -- Queen's University, 2011-11-28 17:50:49.432
123

Dyebath reuse in dyeing cotton and polyester/cotton blend yarns

Rao, Sharad Mohan January 1980 (has links)
No description available.
124

A study of direct dyes which decompose on prolonged boiling

Shah, Pravinchandra Tricumji January 1959 (has links)
No description available.
125

Correlation of plasticizer chemical/physical properties to dyeability and finished characteristics of Nomex Aramid fabrics

Gonul, Mahmut January 2000 (has links)
No description available.
126

The sorption of cationic dyes by polyester fibers.

Kelley, Larry Clifford January 1972 (has links)
No description available.
127

A study of the effect of surfactants on the washfastness of disperse-dyed fabric

Loti, Robert Donald January 1971 (has links)
No description available.
128

Molybdenum-containing dyes

Moss, Martha Cecil January 1960 (has links)
No description available.
129

The role of singlet oxygen in the bleaching of cotton

Thompson, Kimberlee Fay January 1996 (has links)
No description available.
130

Dyeing of polyester carpets in reconstituted dyebaths

Wadia, Jimmy Minocher 12 1900 (has links)
No description available.

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