abstract: In the era of artificial intelligent (AI), deep neural networks (DNN) have achieved accuracy on par with humans on a variety of recognition tasks. However, the high computation and storage requirement of DNN training and inference have posed challenges to deploying or locally training the DNNs on mobile and wearable devices. Energy-efficient hardware innovation from circuit to architecture level is required.In this dissertation, a smart electrocardiogram (ECG) processor is first presented for ECG-based authentication as well as cardiac monitoring. The 65nm testchip consumes 1.06 μW at 0.55 V for real-time ECG authentication achieving equal error rate of 1.7% for authentication on an in-house 645-subject database. Next, a couple of SRAM-based in-memory computing (IMC) accelerators for deep learning algorithms are presented. Two single-array macros titled XNOR-SRAM and C3SRAM are based on resistive and capacitive networks for XNOR-ACcumulation (XAC) operations, respectively. XNOR-SRAM and C3SRAM macros in 65nm CMOS achieve energy efficiency of 403 TOPS/W and 672 TOPS/W, respectively. Built on top of these two single-array macro designs, two multi-array architectures are presented. The XNOR-SRAM based architecture titled “Vesti” is designed to support configurable multibit activations and large-scale DNNs seamlessly. Vesti employs double-buffering with two groups of in-memory computing SRAMs, effectively hiding the write latency of IMC SRAMs. The Vesti accelerator in 65nm CMOS achieves energy consumption of <20 nJ for MNIST classification and <40μJ for CIFAR-10 classification at 1.0 V supply. More recently, a programmable IMC accelerator (PIMCA) integrating 108 C3SRAM macros of a total size of 3.4 Mb is proposed. The28nm prototype chip achieves system-level energy efficiency of 437/62 TOPS/W at 40 MHz, 1 V supply for DNNs with 1b/2b precision. In addition to the IMC works, this dissertation also presents a convolutional neural network (CNN) learning processor, which accelerates the stochastic gradient descent (SGD) with momentum based training algorithm in 16-bit fixed-point precision. The65nm CNN learning processor achieves peak energy efficiency of 2.6 TOPS/W for16-bit fixed-point operations, consuming 10.45 mW at 0.55 V. In summary, in this dissertation, several hardware innovations from circuit to architecture level are presented, exploiting the reduced algorithm complexity with pruning and low-precision quantization techniques. In particular, macro-level and system-level SRAM based IMC works presented in this dissertation show that SRAM based IMC is one of the promising solutions for energy-efficient intelligent systems. / Dissertation/Thesis / Doctoral Dissertation Electrical Engineering 2020