Sensorimotor integration (SMI) is the ability of the central nervous system (CNS) to integrate afferent (incoming) information from different body parts and formulate appropriate motor output to muscles. Effective sensorimotor integration is essential when learning new skills and when performing tasks at home and in the workplace (Rothwell &Rosenkranz, 2005). The overall aim of this thesis is to investigate the effect of acute experimental pain on sensorimotor processing. The primary outcome is the effect of acute experimental pain on somatosensory evoked potential (SEP) peaks. Secondary outcomes include the effect of pain on motor performance and the interactive effect of pain and motor training on SEP peaks. As expected for the placebo condition, no significant differences were found in any of the post-placebo peaks. Contrary to what was expected for the placebo condition, the only peak to be significantly different post-motor learning was the N24 peak. Contrary to what was expected, there were no significant differences for any of the peaks following capsaicin application. One of the secondary outcomes was the interactive effect of pain and motor learning on SEP peaks. The only peak to show any significant differences post-intervention/post-motor learning was the N24 peak. Another secondary outcome was the effect of pain on motor performance. In terms of accuracy, no significant differences were found for either condition following motor learning. However, the data does show a trend towards improved accuracy for the subjects in the intervention group while the subjects in the placebo show a trend towards decreased accuracy. As expected, there was a significant decrease in reaction time for both conditions post-motor learning. However, contrary to what was expected, reaction time decreased to a greater extent in the intervention condition as compared to the placebo condition. It was anticipated that the reaction time would decrease to a greater extent in the placebo condition as it was hypothesized that pain would negatively impact motor performance. It is suspected that the effect of the pain induced by the capsaicin made the motor training task more difficult and participants would have had to focus greater attentional resources to learn the task which lead to the enhanced performance following motor training. / UOIT

Low back pain is characterised by loss of ability to carry out everyday tasks, the disruption of life plans, and psychological distress as well as pain. This study examined the adaptation of individuals with low back pain. In a departure from established models used to study and understand illness representation and adjustment, this study used a personal projects approach to examine the relationship between individuals' appraisals of projects and their functional adaptation to low back pain in the context of their day-to-day goal-directed activities. A functional personal project system was proposed; specifically, those individuals whose project dispositions were highly concordant and socially oriented would have better function and health. For people dealing with low back pain, it was expected that these dispositions, and personal competency, would enhance adaptation. Conversely, poor adaptive abilities, such as difficulties with physical function, social function, and poorer health, would be associated condition-specific perceptions of pain and negative appraisals of project stress[.] The results showed there was a relationship between personal project dispositions and functional ability, well-being, and perceived general health of individuals with low back pain. The results did not confirm that a functional project system possessed adaptive benefits. However, the appraisal of pain as salient to the progress and success of projects and stressfulness of personal projects were predictive of limited function and poorer health. Notably, all aspects of function, both social and physical, were associated with pain-salience cognition. Furthermore, pain salience cognition was still predictive of function after traditional predictors of low back pain disability, pain severity or pain-related fear, were included in the analysis. The significance of the relationship of pain and negative appraisals of the effect of pain on performance supports functional self-efficacy and pain-related fears models used to explain disability level in individuals with low back pain. Since this personal projects analysis was an integrated assessment of individuals' dispositions in the context of participants' everyday lives, it was concluded that pain salience and stressfulness of projects outweighed any advantages offered by their other dispositions in negotiating the participant's personal projects.