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Increasing elastin fibre production in a tissue engineered mesh for pelvic floor surgeryOsman, N., Roman, S., Sefat, Farshid, Bullock, A.J., Chapple, C.R. January 2014 (has links)
Yes / Polypropylene mesh for pelvic floor surgery is associated with serious complications ( e.g. erosion). A biodegradable tissue engineered mesh composed of a polylactic acid (PLA) scaffold seeded with autologous cells is a promising alternative.
However, thus far elastin content (important for elastic recoil) in this tissue has been low. We aimed to increase elastin expression and test the resultant tensile properties.
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