Neurological diseases in newborns are usually first revealed by seizures, which are characterised by a synchronous discharge of a large number of neurons. Failure to control seizures may lead to brain damage or even death. The importance of this problem prompted many researchers to look for accurate automatic methods for seizure detection. Nonstationarity and multicomponent behaviour of newborn EEG signals made this task very challenging. The significant overlap in the characteristic of background and seizure activities in newborn EEG signals added to the difficulty of seizure detection. This research uses time-frequency based methods for automatic seizure detection. Since time-frequency signal analysis methods use joint representation in both time and frequency domains, they proved to be very suitable for analysis and processing of nonstationary and multicomponent signals such as newborn EEG. Before using any seizure detector, the EEG data is pre-processed in order to reduce the noise effects using a time-frequency based technique. The proposed method is based on the singular value decomposition (SVD) technique applied to the matrix representing the time-frequency distribution (TFD) of the EEG signal. It has been shown that by appropriately filtering the singular vectors associated with the TFD, one can effectively enhance the desired information embedded in the signal. Neonatal EEG seizures can have signatures in both low frequency (lower than 10 Hz) and high frequency (higher than 70 Hz) areas. The seizure detection techniques proposed in the literature concentrated on using either low frequency or high frequency signatures but not both simultaneously. These methods tend to miss the seizures that reveal themselves only in one of the two frequency areas. In this research, we propose a detection method that uses seizure features in both low and high frequency areas. To detect EEG seizures using the low frequency signatures, an SVD-based technique is employed. The technique uses the estimated distribution function of the singular vectors associated with the time-frequency distribution of EEG epochs to discriminate between seizure and nonseizure patterns. The high frequency signatures of seizures are mostly the result of spike events in the EEG signals. To detect these spike events, the signal is mapped into the TF domain. The high instantaneous energy of spikes is reflected as a localised energy in the high frequency area of the TF domain. Consequently, a spike can be seen as a ridge in this area of the TF domain. It has been shown that during seizure activity there is regularity in the distribution of the interspike intervals. This feature has been used as the basis for discriminating between seizure and nonseizure patterns. The performance results obtained by applying the proposed methods on EEG signals extracted from a number of newborns show the superiority of these methods over the existing ones.

Most signal processing methods were developed for continuous signals. Digital devices, such as the computer, process only discrete signals. This dissertation proposes new techniques to accurately define and efficiently implement an important signal processing method---the time--frequency distribution (TFD)---using discrete signals. The TFD represents a signal in the joint time--frequency domain. Because these distributions are a function of both time and frequency they, unlike traditional signal processing methods, can display frequency content that changes over time. TFDs have been used successfully in many signal processing applications as almost all real-world signals have time-varying frequency content. Although TFDs are well defined for continuous signals, defining and computing a TFD for discrete signals is problematic. This work overcomes these problems by making contributions to the definition, computation, and application of discrete TFDs. The first contribution is a new discrete definition of TFDs. A discrete TFD (DTFD) should be free from the sampling-related distortion known as aliasing and satisfy all the important mathematical properties that the continuous TFD satisfies. Many different DTFD definitions exist but none come close to attaining this ideal. I propose three new components which make up the DTFD: 1) a new discrete Wigner--Ville distribution (DWVD) definition which satisfies all properties, 2) a new discrete analytic signal which minimises aliasing in the DWVD, and 3) a new method to define and convolve the discrete kernel with the DWVD to produce the DTFD. The result: a DTFD definition that, relative to the existing definitions, better approximates the ideal DTFD. The second contribution is two sets of computationally efficient algorithms to compute the proposed DTFD. The first set of algorithms computes the DTFD exactly; the second set requires less memory than the first set by computing time- and, or frequency-decimated versions of the DTFD. Both sets of algorithms reduce the computational load by exploiting symmetries in the DTFD and by constructing kernel-specific algorithms for four different kernel types. The third, and final, contribution is a biomedical application for the proposed DTFD and algorithms. This application is to accurately detect seizure events in newborn electroencephalogram (EEG) signals. Existing detection methods do not perform well enough for use in a clinical setting. I propose a new method which is more robust than existing methods and show how using the proposed DTFD, comparative to an existing DTFD, improves detection performance for this method. In summary, this dissertation makes practical contributions to the area of time--frequency signal processing by proposing an improved DTFD definition, efficient DTFD algorithms, and an improved newborn EEG seizure detection method using DTFDs.

Most signal processing methods were developed for continuous signals. Digital devices, such as the computer, process only discrete signals. This dissertation proposes new techniques to accurately define and efficiently implement an important signal processing method---the time--frequency distribution (TFD)---using discrete signals. The TFD represents a signal in the joint time--frequency domain. Because these distributions are a function of both time and frequency they, unlike traditional signal processing methods, can display frequency content that changes over time. TFDs have been used successfully in many signal processing applications as almost all real-world signals have time-varying frequency content. Although TFDs are well defined for continuous signals, defining and computing a TFD for discrete signals is problematic. This work overcomes these problems by making contributions to the definition, computation, and application of discrete TFDs. The first contribution is a new discrete definition of TFDs. A discrete TFD (DTFD) should be free from the sampling-related distortion known as aliasing and satisfy all the important mathematical properties that the continuous TFD satisfies. Many different DTFD definitions exist but none come close to attaining this ideal. I propose three new components which make up the DTFD: 1) a new discrete Wigner--Ville distribution (DWVD) definition which satisfies all properties, 2) a new discrete analytic signal which minimises aliasing in the DWVD, and 3) a new method to define and convolve the discrete kernel with the DWVD to produce the DTFD. The result: a DTFD definition that, relative to the existing definitions, better approximates the ideal DTFD. The second contribution is two sets of computationally efficient algorithms to compute the proposed DTFD. The first set of algorithms computes the DTFD exactly; the second set requires less memory than the first set by computing time- and, or frequency-decimated versions of the DTFD. Both sets of algorithms reduce the computational load by exploiting symmetries in the DTFD and by constructing kernel-specific algorithms for four different kernel types. The third, and final, contribution is a biomedical application for the proposed DTFD and algorithms. This application is to accurately detect seizure events in newborn electroencephalogram (EEG) signals. Existing detection methods do not perform well enough for use in a clinical setting. I propose a new method which is more robust than existing methods and show how using the proposed DTFD, comparative to an existing DTFD, improves detection performance for this method. In summary, this dissertation makes practical contributions to the area of time--frequency signal processing by proposing an improved DTFD definition, efficient DTFD algorithms, and an improved newborn EEG seizure detection method using DTFDs.

Most signal processing methods were developed for continuous signals. Digital devices, such as the computer, process only discrete signals. This dissertation proposes new techniques to accurately define and efficiently implement an important signal processing method---the time--frequency distribution (TFD)---using discrete signals. The TFD represents a signal in the joint time--frequency domain. Because these distributions are a function of both time and frequency they, unlike traditional signal processing methods, can display frequency content that changes over time. TFDs have been used successfully in many signal processing applications as almost all real-world signals have time-varying frequency content. Although TFDs are well defined for continuous signals, defining and computing a TFD for discrete signals is problematic. This work overcomes these problems by making contributions to the definition, computation, and application of discrete TFDs. The first contribution is a new discrete definition of TFDs. A discrete TFD (DTFD) should be free from the sampling-related distortion known as aliasing and satisfy all the important mathematical properties that the continuous TFD satisfies. Many different DTFD definitions exist but none come close to attaining this ideal. I propose three new components which make up the DTFD: 1) a new discrete Wigner--Ville distribution (DWVD) definition which satisfies all properties, 2) a new discrete analytic signal which minimises aliasing in the DWVD, and 3) a new method to define and convolve the discrete kernel with the DWVD to produce the DTFD. The result: a DTFD definition that, relative to the existing definitions, better approximates the ideal DTFD. The second contribution is two sets of computationally efficient algorithms to compute the proposed DTFD. The first set of algorithms computes the DTFD exactly; the second set requires less memory than the first set by computing time- and, or frequency-decimated versions of the DTFD. Both sets of algorithms reduce the computational load by exploiting symmetries in the DTFD and by constructing kernel-specific algorithms for four different kernel types. The third, and final, contribution is a biomedical application for the proposed DTFD and algorithms. This application is to accurately detect seizure events in newborn electroencephalogram (EEG) signals. Existing detection methods do not perform well enough for use in a clinical setting. I propose a new method which is more robust than existing methods and show how using the proposed DTFD, comparative to an existing DTFD, improves detection performance for this method. In summary, this dissertation makes practical contributions to the area of time--frequency signal processing by proposing an improved DTFD definition, efficient DTFD algorithms, and an improved newborn EEG seizure detection method using DTFDs.

Most signal processing methods were developed for continuous signals. Digital devices, such as the computer, process only discrete signals. This dissertation proposes new techniques to accurately define and efficiently implement an important signal processing method---the time--frequency distribution (TFD)---using discrete signals. The TFD represents a signal in the joint time--frequency domain. Because these distributions are a function of both time and frequency they, unlike traditional signal processing methods, can display frequency content that changes over time. TFDs have been used successfully in many signal processing applications as almost all real-world signals have time-varying frequency content. Although TFDs are well defined for continuous signals, defining and computing a TFD for discrete signals is problematic. This work overcomes these problems by making contributions to the definition, computation, and application of discrete TFDs. The first contribution is a new discrete definition of TFDs. A discrete TFD (DTFD) should be free from the sampling-related distortion known as aliasing and satisfy all the important mathematical properties that the continuous TFD satisfies. Many different DTFD definitions exist but none come close to attaining this ideal. I propose three new components which make up the DTFD: 1) a new discrete Wigner--Ville distribution (DWVD) definition which satisfies all properties, 2) a new discrete analytic signal which minimises aliasing in the DWVD, and 3) a new method to define and convolve the discrete kernel with the DWVD to produce the DTFD. The result: a DTFD definition that, relative to the existing definitions, better approximates the ideal DTFD. The second contribution is two sets of computationally efficient algorithms to compute the proposed DTFD. The first set of algorithms computes the DTFD exactly; the second set requires less memory than the first set by computing time- and, or frequency-decimated versions of the DTFD. Both sets of algorithms reduce the computational load by exploiting symmetries in the DTFD and by constructing kernel-specific algorithms for four different kernel types. The third, and final, contribution is a biomedical application for the proposed DTFD and algorithms. This application is to accurately detect seizure events in newborn electroencephalogram (EEG) signals. Existing detection methods do not perform well enough for use in a clinical setting. I propose a new method which is more robust than existing methods and show how using the proposed DTFD, comparative to an existing DTFD, improves detection performance for this method. In summary, this dissertation makes practical contributions to the area of time--frequency signal processing by proposing an improved DTFD definition, efficient DTFD algorithms, and an improved newborn EEG seizure detection method using DTFDs.

Most signal processing methods were developed for continuous signals. Digital devices, such as the computer, process only discrete signals. This dissertation proposes new techniques to accurately define and efficiently implement an important signal processing method---the time--frequency distribution (TFD)---using discrete signals. The TFD represents a signal in the joint time--frequency domain. Because these distributions are a function of both time and frequency they, unlike traditional signal processing methods, can display frequency content that changes over time. TFDs have been used successfully in many signal processing applications as almost all real-world signals have time-varying frequency content. Although TFDs are well defined for continuous signals, defining and computing a TFD for discrete signals is problematic. This work overcomes these problems by making contributions to the definition, computation, and application of discrete TFDs. The first contribution is a new discrete definition of TFDs. A discrete TFD (DTFD) should be free from the sampling-related distortion known as aliasing and satisfy all the important mathematical properties that the continuous TFD satisfies. Many different DTFD definitions exist but none come close to attaining this ideal. I propose three new components which make up the DTFD: 1) a new discrete Wigner--Ville distribution (DWVD) definition which satisfies all properties, 2) a new discrete analytic signal which minimises aliasing in the DWVD, and 3) a new method to define and convolve the discrete kernel with the DWVD to produce the DTFD. The result: a DTFD definition that, relative to the existing definitions, better approximates the ideal DTFD. The second contribution is two sets of computationally efficient algorithms to compute the proposed DTFD. The first set of algorithms computes the DTFD exactly; the second set requires less memory than the first set by computing time- and, or frequency-decimated versions of the DTFD. Both sets of algorithms reduce the computational load by exploiting symmetries in the DTFD and by constructing kernel-specific algorithms for four different kernel types. The third, and final, contribution is a biomedical application for the proposed DTFD and algorithms. This application is to accurately detect seizure events in newborn electroencephalogram (EEG) signals. Existing detection methods do not perform well enough for use in a clinical setting. I propose a new method which is more robust than existing methods and show how using the proposed DTFD, comparative to an existing DTFD, improves detection performance for this method. In summary, this dissertation makes practical contributions to the area of time--frequency signal processing by proposing an improved DTFD definition, efficient DTFD algorithms, and an improved newborn EEG seizure detection method using DTFDs.

Most signal processing methods were developed for continuous signals. Digital devices, such as the computer, process only discrete signals. This dissertation proposes new techniques to accurately define and efficiently implement an important signal processing method---the time--frequency distribution (TFD)---using discrete signals. The TFD represents a signal in the joint time--frequency domain. Because these distributions are a function of both time and frequency they, unlike traditional signal processing methods, can display frequency content that changes over time. TFDs have been used successfully in many signal processing applications as almost all real-world signals have time-varying frequency content. Although TFDs are well defined for continuous signals, defining and computing a TFD for discrete signals is problematic. This work overcomes these problems by making contributions to the definition, computation, and application of discrete TFDs. The first contribution is a new discrete definition of TFDs. A discrete TFD (DTFD) should be free from the sampling-related distortion known as aliasing and satisfy all the important mathematical properties that the continuous TFD satisfies. Many different DTFD definitions exist but none come close to attaining this ideal. I propose three new components which make up the DTFD: 1) a new discrete Wigner--Ville distribution (DWVD) definition which satisfies all properties, 2) a new discrete analytic signal which minimises aliasing in the DWVD, and 3) a new method to define and convolve the discrete kernel with the DWVD to produce the DTFD. The result: a DTFD definition that, relative to the existing definitions, better approximates the ideal DTFD. The second contribution is two sets of computationally efficient algorithms to compute the proposed DTFD. The first set of algorithms computes the DTFD exactly; the second set requires less memory than the first set by computing time- and, or frequency-decimated versions of the DTFD. Both sets of algorithms reduce the computational load by exploiting symmetries in the DTFD and by constructing kernel-specific algorithms for four different kernel types. The third, and final, contribution is a biomedical application for the proposed DTFD and algorithms. This application is to accurately detect seizure events in newborn electroencephalogram (EEG) signals. Existing detection methods do not perform well enough for use in a clinical setting. I propose a new method which is more robust than existing methods and show how using the proposed DTFD, comparative to an existing DTFD, improves detection performance for this method. In summary, this dissertation makes practical contributions to the area of time--frequency signal processing by proposing an improved DTFD definition, efficient DTFD algorithms, and an improved newborn EEG seizure detection method using DTFDs.

Most signal processing methods were developed for continuous signals. Digital devices, such as the computer, process only discrete signals. This dissertation proposes new techniques to accurately define and efficiently implement an important signal processing method---the time--frequency distribution (TFD)---using discrete signals. The TFD represents a signal in the joint time--frequency domain. Because these distributions are a function of both time and frequency they, unlike traditional signal processing methods, can display frequency content that changes over time. TFDs have been used successfully in many signal processing applications as almost all real-world signals have time-varying frequency content. Although TFDs are well defined for continuous signals, defining and computing a TFD for discrete signals is problematic. This work overcomes these problems by making contributions to the definition, computation, and application of discrete TFDs. The first contribution is a new discrete definition of TFDs. A discrete TFD (DTFD) should be free from the sampling-related distortion known as aliasing and satisfy all the important mathematical properties that the continuous TFD satisfies. Many different DTFD definitions exist but none come close to attaining this ideal. I propose three new components which make up the DTFD: 1) a new discrete Wigner--Ville distribution (DWVD) definition which satisfies all properties, 2) a new discrete analytic signal which minimises aliasing in the DWVD, and 3) a new method to define and convolve the discrete kernel with the DWVD to produce the DTFD. The result: a DTFD definition that, relative to the existing definitions, better approximates the ideal DTFD. The second contribution is two sets of computationally efficient algorithms to compute the proposed DTFD. The first set of algorithms computes the DTFD exactly; the second set requires less memory than the first set by computing time- and, or frequency-decimated versions of the DTFD. Both sets of algorithms reduce the computational load by exploiting symmetries in the DTFD and by constructing kernel-specific algorithms for four different kernel types. The third, and final, contribution is a biomedical application for the proposed DTFD and algorithms. This application is to accurately detect seizure events in newborn electroencephalogram (EEG) signals. Existing detection methods do not perform well enough for use in a clinical setting. I propose a new method which is more robust than existing methods and show how using the proposed DTFD, comparative to an existing DTFD, improves detection performance for this method. In summary, this dissertation makes practical contributions to the area of time--frequency signal processing by proposing an improved DTFD definition, efficient DTFD algorithms, and an improved newborn EEG seizure detection method using DTFDs.

Most signal processing methods were developed for continuous signals. Digital devices, such as the computer, process only discrete signals. This dissertation proposes new techniques to accurately define and efficiently implement an important signal processing method---the time--frequency distribution (TFD)---using discrete signals. The TFD represents a signal in the joint time--frequency domain. Because these distributions are a function of both time and frequency they, unlike traditional signal processing methods, can display frequency content that changes over time. TFDs have been used successfully in many signal processing applications as almost all real-world signals have time-varying frequency content. Although TFDs are well defined for continuous signals, defining and computing a TFD for discrete signals is problematic. This work overcomes these problems by making contributions to the definition, computation, and application of discrete TFDs. The first contribution is a new discrete definition of TFDs. A discrete TFD (DTFD) should be free from the sampling-related distortion known as aliasing and satisfy all the important mathematical properties that the continuous TFD satisfies. Many different DTFD definitions exist but none come close to attaining this ideal. I propose three new components which make up the DTFD: 1) a new discrete Wigner--Ville distribution (DWVD) definition which satisfies all properties, 2) a new discrete analytic signal which minimises aliasing in the DWVD, and 3) a new method to define and convolve the discrete kernel with the DWVD to produce the DTFD. The result: a DTFD definition that, relative to the existing definitions, better approximates the ideal DTFD. The second contribution is two sets of computationally efficient algorithms to compute the proposed DTFD. The first set of algorithms computes the DTFD exactly; the second set requires less memory than the first set by computing time- and, or frequency-decimated versions of the DTFD. Both sets of algorithms reduce the computational load by exploiting symmetries in the DTFD and by constructing kernel-specific algorithms for four different kernel types. The third, and final, contribution is a biomedical application for the proposed DTFD and algorithms. This application is to accurately detect seizure events in newborn electroencephalogram (EEG) signals. Existing detection methods do not perform well enough for use in a clinical setting. I propose a new method which is more robust than existing methods and show how using the proposed DTFD, comparative to an existing DTFD, improves detection performance for this method. In summary, this dissertation makes practical contributions to the area of time--frequency signal processing by proposing an improved DTFD definition, efficient DTFD algorithms, and an improved newborn EEG seizure detection method using DTFDs.

Most signal processing methods were developed for continuous signals. Digital devices, such as the computer, process only discrete signals. This dissertation proposes new techniques to accurately define and efficiently implement an important signal processing method---the time--frequency distribution (TFD)---using discrete signals. The TFD represents a signal in the joint time--frequency domain. Because these distributions are a function of both time and frequency they, unlike traditional signal processing methods, can display frequency content that changes over time. TFDs have been used successfully in many signal processing applications as almost all real-world signals have time-varying frequency content. Although TFDs are well defined for continuous signals, defining and computing a TFD for discrete signals is problematic. This work overcomes these problems by making contributions to the definition, computation, and application of discrete TFDs. The first contribution is a new discrete definition of TFDs. A discrete TFD (DTFD) should be free from the sampling-related distortion known as aliasing and satisfy all the important mathematical properties that the continuous TFD satisfies. Many different DTFD definitions exist but none come close to attaining this ideal. I propose three new components which make up the DTFD: 1) a new discrete Wigner--Ville distribution (DWVD) definition which satisfies all properties, 2) a new discrete analytic signal which minimises aliasing in the DWVD, and 3) a new method to define and convolve the discrete kernel with the DWVD to produce the DTFD. The result: a DTFD definition that, relative to the existing definitions, better approximates the ideal DTFD. The second contribution is two sets of computationally efficient algorithms to compute the proposed DTFD. The first set of algorithms computes the DTFD exactly; the second set requires less memory than the first set by computing time- and, or frequency-decimated versions of the DTFD. Both sets of algorithms reduce the computational load by exploiting symmetries in the DTFD and by constructing kernel-specific algorithms for four different kernel types. The third, and final, contribution is a biomedical application for the proposed DTFD and algorithms. This application is to accurately detect seizure events in newborn electroencephalogram (EEG) signals. Existing detection methods do not perform well enough for use in a clinical setting. I propose a new method which is more robust than existing methods and show how using the proposed DTFD, comparative to an existing DTFD, improves detection performance for this method. In summary, this dissertation makes practical contributions to the area of time--frequency signal processing by proposing an improved DTFD definition, efficient DTFD algorithms, and an improved newborn EEG seizure detection method using DTFDs.